A novel prodrug-based strategy to increase effects of bumetanide in epilepsy von Töllner, Kathrin, Brandt, Claudia, Töpfer, Manuel, Brunhofer, Gerda, Erker, Thomas, Gabriel, Mario, Feit, Peter W., Lindfors, Jenna, Kaila, Kai, Löscher, Wolfgang

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Tariquidar and elacridar are dose-dependently transported by P-glycoprotein and Bcrp at the blood-brain barrier: a small-animal positron emission tomography and in vitro study von Bankstahl, Jens P, Bankstahl, Marion, Römermann, Kerstin, Wanek, Thomas, Stanek, Johann, Windhorst, Albert D, Fedrowitz, Maren, Erker, Thomas, Müller, Markus, Löscher, Wolfgang, Langer, Oliver, Kuntner, Claudia

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GABAA receptor modulation by piperine and a non-TRPV1 activating derivative von Khom, Sophia, Strommer, Barbara, Schöffmann, Angela, Hintersteiner, Juliane, Baburin, Igor, Erker, Thomas, Schwarz, Thomas, Schwarzer, Christoph, Zaugg, Janine, Hamburger, Matthias, Hering, Steffen

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Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity von Bollmann, Franziska, Art, Julia, Henke, Jenny, Schrick, Katharina, Besche, Verena, Bros, Matthias, Li, Huige, Siuda, Daniel, Handler, Norbert, Bauer, Florian, Erker, Thomas, Behnke, Felix, Mönch, Bettina, Härdle, Lorena, Hoffmann, Markus, Chen, Ching-Yi, Förstermann, Ulrich, Dirsch, Verena M, Werz, Oliver, Kleinert, Hartmut, Pautz, Andrea

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Role of NKCC1 Activity in Glioma K(+)Homeostasis and Cell Growth: New Insights With the Bumetanide-Derivative STS66 von Luo, Lanxin, Wang, Jun, Ding, Dawei, Hasan, Md Nabiul, Yang, Sung-Sen, Lin, Shih-Hua, Schreppel, Philipp, Sun, Baoshan, Yin, Yan, Erker, Thomas, Sun, Dandan

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Novel Promising Estrogenic Receptor Modulators: Cytotoxic and Estrogenic Activity of Benzanilides and Dithiobenzanilides von Kucinska, Malgorzata, Giron, Maria-Dolores, Piotrowska, Hanna, Lisiak, Natalia, Granig, Walter H, Lopez-Jaramillo, Francisco-Javier, Salto, Rafael, Murias, Marek, Erker, Thomas

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Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor von Bauer, Florian, Kuntner, Claudia, Bankstahl, Jens P., Wanek, Thomas, Bankstahl, Marion, Stanek, Johann, Mairinger, Severin, Dörner, Bernd, Löscher, Wolfgang, Müller, Markus, Erker, Thomas, Langer, Oliver

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Synthesis and Small-Animal Positron Emission Tomography Evaluation of [11C]-Elacridar As a Radiotracer to Assess the Distribution of P-Glycoprotein at the Blood−Brain Barrier von Dörner, Bernd, Kuntner, Claudia, Bankstahl, Jens P, Bankstahl, Marion, Stanek, Johann, Wanek, Thomas, Stundner, Gloria, Mairinger, Severin, Löscher, Wolfgang, Müller, Markus, Langer, Oliver, Erker, Thomas

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Foam cell specific LXRα ligand von Feldmann, Radmila, Geikowski, Anne, Weidner, Christopher, Witzke, Annabell, Kodelja, Vitam, Schwarz, Thomas, Gabriel, Mario, Erker, Thomas, Sauer, Sascha

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Antioxidant activity of resveratrol, piceatannol and 3,3',4,4',5,5'-hexahydroxy-trans-stilbene in three leukemia cell lines von OVESNA, Zdenka, KOZICS, Katarina, BADER, Yvonne, SAIKO, Philipp, HANDLER, Norbert, ERKER, Thomas, SZEKERES, Thomas

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Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors von Handler, Norbert, Jaeger, Walter, Puschacher, Helmut, Leisser, Klaus, Erker, Thomas

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Resveratrol blocks Akt activation in angiotensin II-or EGF-stimulated vascular smooth muscle cells in a redox-independent manner von SCHREINER, Cornelia E, KUMERZ, Mario, GESSLBAUER, Julia, SCHACHNER, Daniel, JOA, Helge, ERKER, Thomas, ATANASOV, Atanas G, HEISS, Elke H, DIRSCH, Verena M

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Impaired chloride homeostasis in epilepsy: Molecular basis, impact on treatment, and current treatment approaches von Auer, Theresa, Schreppel, Philipp, Erker, Thomas, Schwarzer, Christoph

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Functional characterization of novel bumetanide derivatives for epilepsy treatment von Auer, Theresa, Schreppel, Philipp, Erker, Thomas, Schwarzer, Christoph

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Novel Resveratrol Derivatives Induce Apoptosis and Cause Cell Cycle Arrest in Prostate Cancer Cell Lines von Horvath, Z, Marihart-Fazekas, S, Saiko, P, Grusch, M, Oezsuey, M, Harik, M, Handler, N, Erker, T, Jaeger, W, Fritzer-Szekeres, M, Djavan, B, Szekeres, T

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Multiple blood-brain barrier transport mechanisms limit bumetanide accumulation, and therapeutic potential, in the mammalian brain von Römermann, Kerstin, Fedrowitz, Maren, Hampel, Philip, Kaczmarek, Edith, Töllner, Kathrin, Erker, Thomas, Sweet, Douglas H., Löscher, Wolfgang

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Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein von Parveen, Zahida, Brunhofer, Gerda, Jabeen, Ishrat, Erker, Thomas, Chiba, Peter, Ecker, Gerhard F.

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A Novel Na+-K+-Cl− Cotransporter 1 Inhibitor STS66 Reduces Brain Damage in Mice After Ischemic Stroke von Huang, Huachen, Bhuiyan, Mohammad Iqbal H., Jiang, Tong, Song, Shanshan, Shankar, Sandhya, Taheri, Taraneh, Li, Eric, Schreppel, Philipp, Hintersteininger, Michael, Yang, Sung-Sen, Lin, Shih-Hua, Molyneaux, Bradley J., Zhang, Zhongling, Erker, Thomas, Sun, Dandan

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The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines von Kucinska, Malgorzata, Mieszczak, Helena, Piotrowska-Kempisty, Hanna, Kaczmarek, Mariusz, Granig, Walter, Murias, Marek, Erker, Thomas

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The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice von Erker, Thomas, Brandt, Claudia, Töllner, Kathrin, Schreppel, Philipp, Twele, Friederike, Schidlitzki, Alina, Löscher, Wolfgang

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