Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells von Chung, Liam, Thiele Orberg, Erik, Geis, Abby L., Chan, June L., Fu, Kai, DeStefano Shields, Christina E., Dejea, Christine M., Fathi, Payam, Chen, Jie, Finard, Benjamin B., Tam, Ada J., McAllister, Florencia, Fan, Hongni, Wu, Xinqun, Ganguly, Sudipto, Lebid, Andriana, Metz, Paul, Van Meerbeke, Sara W., Huso, David L., Wick, Elizabeth C., Pardoll, Drew M., Wan, Fengyi, Wu, Shaoguang, Sears, Cynthia L., Housseau, Franck

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Type I interferon signaling before hematopoietic stem cell transplantation lowers donor T cell activation via reduced allogenicity of recipient cells von Fischer, Julius C., Bscheider, Michael, Göttert, Sascha, Thiele Orberg, Erik, Combs, Stephanie E., Bassermann, Florian, Heidegger, Simon, Haas, Tobias, Poeck, Hendrik

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Interleukin-17 and type 17 helper T cells in cancer management and research von Llosa, Nicolas J, Geis, Abby L, Thiele Orberg, Erik, Housseau, Franck

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The role of type I interferon in prophylaxis of graft-versus-host disease von Thiele Orberg, Erik, Poeck, Hendrik

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Immunomodulatory microbial metabolites as potential predictors of stem-cell transplantation outcomes

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Microbial-Derived Metabolites Drive Protective Type-I Interferon Responses in Models of Gut Epithelial Damage and Limit Graft-Versus-Host Disease von Thiele Orberg, Erik, Göttert, Sascha, Poeck, Hendrik

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The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis von Thiele Orberg, E, Fan, H, Tam, A J, Dejea, C M, Destefano Shields, C E, Wu, S, Chung, L, Finard, B B, Wu, X, Fathi, P, Ganguly, S, Fu, J, Pardoll, D M, Sears, C L, Housseau, F

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Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis von Göttert, Sascha, Thiele-Orberg, Erik, Fan, Kaiji, Ghimire, Sakhila, Heinrich, Paul, Herr, Wolfgang, Heidegger, Simon, Holler, Ernst, Poeck, Hendrik

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IFN-Gamma Is Crucial for the Counterbalance of T Cell-Mediated Injury to the Intestinal Stem Cell Compartment By Regulatory T Cells in Mice and Humans von Göttert, Sascha, Fischer, Julius Clemens, Eisenkolb, Gabriel, Thiele Orberg, Erik, Jarosch, Sebastian, Holler, Ernst, Busch, Dirk, Heidegger, Simon, Poeck, Hendrik

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Type I Interferon Signaling before Hematopoietic Stem Cell Transplantation Lowers Donor T Cell Activation Via Reduced Allogenicity of Recipient Cells von Thiele Orberg, Erik, Fischer, Julius Clemens, Göttert, Sascha, Bassermann, Florian, Poeck, Hendrik

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Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease von Thiele Orberg, Erik, Göttert, Sascha, Hiergeist, Andreas, Meedt, Elisabeth, Kleigrewe, Karin, Herr, Wolfgang, Bassermann, Florian, Gessner, Andre, Holler, Ernst, Heidegger, Simon, Poeck, Hendrik

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Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients von Thiele Orberg, Erik, Meedt, Elisabeth, Hiergeist, Andreas, Xue, Jinling, Heinrich, Paul, Ghimire, Sakhila, Miltiadous, Oriana, Lindner, Sarah, Schwarz, Alix, Janssen, Klaus-Peter, Herhaus, Peter, Verbeek, Mareike, van den Brink, Marcel R.M., Weber, Daniela, Edinger, Matthias, Wolff, Daniel, Kleigrewe, Karin, Herr, Wolfgang, Bassermann, Florian, Gessner, André, Deng, Li, Holler, Ernst, Poeck, Hendrik

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Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease von Thiele Orberg, Erik, Meedt, Elisabeth, Hiergeist, Andreas, Xue, Jinling, Ghimire, Sakhila, Tiefgraber, Melanie, Eismann, Tina, Göldel, Sophia, Herhaus, Peter, Verbeek, Mareike, Bassermann, Florian, Quante, Michael, Weber, Daniela, Edinger, Matthias, Wolff, Daniel, Herr, Wolfgang, Deng, Li, Gessner, André, Holler, Ernst, Poeck, Hendrik

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Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation P... von Thiele Orberg, Erik, Meedt, Elisabeth, Hiergeist, Andreas, Xue, Jinling, Heinrich, Paul, Ghimire, Sakhila, Tiefgraber, Melanie, Göldel, Sophia, Eismann, Tina, Schwarz, Alix, Jarosch, Sebastian, Steiger, Katja, Kleigrewe, Karin, Fischer, Julius Clemens, Janssen, Klaus-Peter, Quante, Michael, Heidegger, Simon, Herhaus, Peter, Verbeek, Mareike, Ruland, Jürgen, Schulz, Christian, Weber, Daniela, Edinger, Matthias, Wolff, Daniel, Busch, Dirk, Herr, Wolfgang, Bassermann, Florian, Deng, Li, Gessner, Andre, Holler, Ernst, Poeck, Hendrik

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The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitors von Joachim, Laura, Göttert, Sascha, Sax, Anna, Steiger, Katja, Neuhaus, Klaus, Heinrich, Paul, Fan, Kaiji, Orberg, Erik Thiele, Kleigrewe, Karin, Ruland, Jürgen, Bassermann, Florian, Herr, Wolfgang, Posch, Christian, Heidegger, Simon, Poeck, Hendrik

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IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans von Göttert, Sascha, Fischer, Julius Clemens, Eisenkolb, Gabriel, Thiele Orberg, Erik, Busch, Dirk, Jarosch, Sebastian, Holler, Ernst, Engleitner, Thomas, Klostermeier, Lena, Walther, Caroline, Lansink Rotgerink, Laura, Nefzger, Sophie, Reiser, Marianne, Steiger, Katja, Rad, Roland, Combs, Stefanie E., Bassermann, Florian, Heidegger, Simon, Poeck, Hendrik

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Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells von Chung, Liam, Orberg, Erik Thiele, Geis, Abby L., Chan, June L., Fu, Kai, DeStefano Shields, Christina E., Dejea, Christine M., Fathi, Payam, Chen, Jie, Finard, Benjamin B., Tam, Ada J., McAllister, Florencia, Fan, Hongni, Wu, Xinqun, Ganguly, Sudipto, Lebid, Andriana, Metz, Paul, Van Meerbeke, Sara W., Huso, David L., Wick, Elizabeth C., Pardoll, Drew M., Wan, Fengyi, Wu, Shaoguang, Sears, Cynthia L., Housseau, Franck

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The microbial metabolite desaminotyrosine enhances T-cell priming and cancer immunotherapy with immune checkpoint inhibitorsResearch in context von Laura Joachim, Sascha Göttert, Anna Sax, Katja Steiger, Klaus Neuhaus, Paul Heinrich, Kaiji Fan, Erik Thiele Orberg, Karin Kleigrewe, Jürgen Ruland, Florian Bassermann, Wolfgang Herr, Christian Posch, Simon Heidegger, Hendrik Poeck

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Multimodal immune cell phenotyping in GI biopsies reveals microbiome-related T cell modulations in human GvHD von Jarosch, Sebastian, Köhlen, Jan, Ghimire, Sakhila, Orberg, Erik Thiele, Hammel, Monika, Gaag, Doris, Evert, Matthias, Janssen, Klaus-Peter, Hiergeist, Andreas, Gessner, André, Weber, Daniela, Meedt, Elisabeth, Poeck, Hendrik, D’Ippolito, Elvira, Holler, Ernst, Busch, Dirk H.

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Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy von Heidegger, Simon, Stritzke, Florian, Dahl, Sarah, Daßler-Plenker, Juliane, Joachim, Laura, Buschmann, Dominik, Fan, Kaiji, Sauer, Carolin M., Ludwig, Nils, Winter, Christof, Enssle, Stefan, Li, Suqi, Perl, Markus, Görgens, André, Haas, Tobias, Orberg, Erik Thiele, Göttert, Sascha, Wölfel, Catherine, Engleitner, Thomas, Cortés-Ciriano, Isidro, Rad, Roland, Herr, Wolfgang, Giebel, Bernd, Ruland, Jürgen, Bassermann, Florian, Coch, Christoph, Hartmann, Gunther, Poeck, Hendrik

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