Advances in multiphoton microscopy technology von Hoover, Erich E., Squier, Jeff A.

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The pathobiology of perturbed mutant huntingtin protein–protein interactions in Huntington's disease von Wanker, Erich E., Ast, Anne, Schindler, Franziska, Trepte, Philipp, Schnoegl, Sigrid

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EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity von Bieschke, Jan, Russ, Jenny, Friedrich, Ralf P, Ehrnhoefer, Dagmar E, Wobst, Heike, Neugebauer, Katja, Wanker, Erich E

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HIPPIE: Integrating protein interaction networks with experiment based quality scores von Schaefer, Martin H, Fontaine, Jean-Fred, Vinayagam, Arunachalam, Porras, Pablo, Wanker, Erich E, Andrade-Navarro, Miguel A

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HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration von Mielcarek, Michal, Landles, Christian, Weiss, Andreas, Bradaia, Amyaouch, Seredenina, Tamara, Inuabasi, Linda, Osborne, Georgina F, Wadel, Kristian, Touller, Chrystelle, Butler, Rachel, Robertson, Janette, Franklin, Sophie A, Smith, Donna L, Park, Larry, Marks, Paul A, Wanker, Erich E, Olson, Eric N, Luthi-Carter, Ruth, van der Putten, Herman, Beaumont, Vahri, Bates, Gillian P

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Maximizing binary interactome mapping with a minimal number of assays von Choi, Soon Gang, Olivet, Julien, Cassonnet, Patricia, Vidalain, Pierre-Olivier, Luck, Katja, Lambourne, Luke, Spirohn, Kerstin, Lemmens, Irma, Dos Santos, Mélanie, Demeret, Caroline, Jones, Louis, Rangarajan, Sudharshan, Bian, Wenting, Coutant, Eloi P., Janin, Yves L., van der Werf, Sylvie, Trepte, Philipp, Wanker, Erich E., De Las Rivas, Javier, Tavernier, Jan, Twizere, Jean-Claude, Hao, Tong, Hill, David E., Vidal, Marc, Calderwood, Michael A., Jacob, Yves

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Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex von Scior, Annika, Buntru, Alexander, Arnsburg, Kristin, Ast, Anne, Iburg, Manuel, Juenemann, Katrin, Pigazzini, Maria Lucia, Mlody, Barbara, Puchkov, Dmytro, Priller, Josef, Wanker, Erich E, Prigione, Alessandro, Kirstein, Janine

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EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers von Masino, Laura, Lurz, Rudi, Engemann, Sabine, Wanker, Erich E, Pastore, Annalisa, Boeddrich, Annett, Ehrnhoefer, Dagmar E, Bieschke, Jan, Herbst, Martin

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HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2 von Prigione, Alessandro, Rohwer, Nadine, Hoffmann, Sheila, Mlody, Barbara, Drews, Katharina, Bukowiecki, Raul, Blümlein, Katharina, Wanker, Erich E., Ralser, Markus, Cramer, Thorsten, Adjaye, James

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The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios von Wobst, Heike J., Sharma, Apurwa, Diamond, Marc I., Wanker, Erich E., Bieschke, Jan

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A directed protein interaction network for investigating intracellular signal transduction von Vinayagam, Arunachalam, Stelzl, Ulrich, Foulle, Raphaele, Plassmann, Stephanie, Zenkner, Martina, Timm, Jan, Assmus, Heike E, Andrade-Navarro, Miguel A, Wanker, Erich E

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Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks von Schaefer, Martin H, Wanker, Erich E, Andrade-Navarro, Miguel A

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The polyphenol EGCG directly targets intracellular amyloid‐β aggregates and promotes their lysosomal degradation von Secker, Christopher, Motzny, Angelika Y., Kostova, Simona, Buntru, Alexander, Helmecke, Lucas, Reus, Laura, Steinfort, Robert, Brusendorf, Lydia, Boeddrich, Annett, Neuendorf, Nancy, Diez, Lisa, Schmieder, Peter, Schulz, Aline, Czekelius, Constantin, Wanker, Erich E.

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Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders von Lorenz, Carmen, Lesimple, Pierre, Bukowiecki, Raul, Zink, Annika, Inak, Gizem, Mlody, Barbara, Singh, Manvendra, Semtner, Marcus, Mah, Nancy, Auré, Karine, Leong, Megan, Zabiegalov, Oleksandr, Lyras, Ekaterini-Maria, Pfiffer, Vanessa, Fauler, Beatrix, Eichhorst, Jenny, Wiesner, Burkhard, Huebner, Norbert, Priller, Josef, Mielke, Thorsten, Meierhofer, David, Izsvák, Zsuzsanna, Meier, Jochen C., Bouillaud, Frédéric, Adjaye, James, Schuelke, Markus, Wanker, Erich E., Lombès, Anne, Prigione, Alessandro

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Amyloid-β(1–42) Aggregation Initiates Its Cellular Uptake and Cytotoxicity von Jin, Sha, Kedia, Niraja, Illes-Toth, Eva, Haralampiev, Ivan, Prisner, Simon, Herrmann, Andreas, Wanker, Erich E., Bieschke, Jan

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An empirical framework for binary interactome mapping von Tavernier, Jan, Wanker, Erich E, Barabási, Albert-László, Vidal, Marc, Venkatesan, Kavitha, Rual, Jean-François, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, Hao, Tong, Zenkner, Martina, Xin, Xiaofeng, Goh, Kwang-Il, Yildirim, Muhammed A, Simonis, Nicolas, Heinzmann, Kathrin, Gebreab, Fana, Sahalie, Julie M, Cevik, Sebiha, Simon, Christophe, de Smet, Anne-Sophie, Dann, Elizabeth, Smolyar, Alex, Vinayagam, Arunachalam, Yu, Haiyuan, Szeto, David, Borick, Heather, Dricot, Amélie, Klitgord, Niels, Murray, Ryan R, Lin, Chenwei, Lalowski, Maciej, Timm, Jan, Rau, Kirstin, Boone, Charles, Braun, Pascal, Cusick, Michael E, Roth, Frederick P, Hill, David E

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The hunt for huntingtin function: interaction partners tell many different stories von Harjes, Phoebe, Wanker, Erich E

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A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease von Boeddrich, Annett, Haenig, Christian, Neuendorf, Nancy, Blanc, Eric, Ivanov, Andranik, Kirchner, Marieluise, Schleumann, Philipp, Bayraktaroğlu, Irem, Richter, Matthias, Molenda, Christine Mirjam, Sporbert, Anje, Zenkner, Martina, Schnoegl, Sigrid, Suenkel, Christin, Schneider, Luisa-Sophie, Rybak-Wolf, Agnieszka, Kochnowsky, Bianca, Byrne, Lauren M, Wild, Edward J, Nielsen, Jørgen E, Dittmar, Gunnar, Peters, Oliver, Beule, Dieter, Wanker, Erich E

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Molecular architecture of synaptic vesicles von Kravčenko, Uljana, Ruwolt, Max, Kroll, Jana, Yushkevich, Artsemi, Zenkner, Martina, Ruta, Julia, Lotfy, Rowaa, Wanker, Erich E, Rosenmund, Christian, Liu, Fan, Kudryashev, Mikhail

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Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains von Haenig, Christian, Atias, Nir, Taylor, Alexander K., Mazza, Arnon, Schaefer, Martin H., Russ, Jenny, Riechers, Sean-Patrick, Jain, Shushant, Coughlin, Maura, Fontaine, Jean-Fred, Freibaum, Brian D., Brusendorf, Lydia, Zenkner, Martina, Porras, Pablo, Stroedicke, Martin, Schnoegl, Sigrid, Arnsburg, Kristin, Boeddrich, Annett, Pigazzini, Lucia, Heutink, Peter, Taylor, J. Paul, Kirstein, Janine, Andrade-Navarro, Miguel A., Sharan, Roded, Wanker, Erich E.

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