Amyloid beta： structure, biology and structure-based therapeutic development von Chen, Guo-fang, Xu, Ting-hai, Yan, Yan, Zhou, Yu-ren, Jiang, Yi, Melcher, Karsten, Xu, H Eric

Volltext

Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin von Yin, Wanchao, Luan, Xiaodong, Li, Zhihai, Zhou, Ziwei, Wang, Qingxing, Gao, Minqi, Wang, Xiaoxi, Zhou, Fulai, Shi, Jingjing, You, Erli, Liu, Mingliang, Wang, Qingxia, Jiang, Yi, Jiang, Hualiang, Xiao, Gengfu, Zhang, Leike, Yu, Xuekui, Zhang, Shuyang, Eric Xu, H.

Volltext

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase von Byun, Sangwon, Seok, Sunmi, Kim, Young-Chae, Zhang, Yang, Yau, Peter, Iwamori, Naoki, Xu, H. Eric, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim

Volltext

Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir von Yin, Wanchao, Mao, Chunyou, Luan, Xiaodong, Shen, Dan-Dan, Shen, Qingya, Su, Haixia, Wang, Xiaoxi, Zhou, Fulai, Zhao, Wenfeng, Gao, Minqi, Chang, Shenghai, Xie, Yuan-Chao, Tian, Guanghui, Jiang, He-Wei, Tao, Sheng-Ce, Shen, Jingshan, Jiang, Yi, Jiang, Hualiang, Xu, Yechun, Zhang, Shuyang, Zhang, Yan, Xu, H. Eric

Volltext

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy von Duan, Jia, Shen, Dan-dan, Zhou, X. Edward, Bi, Peng, Liu, Qiu-feng, Tan, Yang-xia, Zhuang, You-wen, Zhang, Hui-bing, Xu, Pei-yu, Huang, Si-Jie, Ma, Shan-shan, He, Xin-heng, Melcher, Karsten, Zhang, Yan, Xu, H. Eric, Jiang, Yi

Volltext

Structure and dynamics of the active human parathyroid hormone receptor-1 von Zhao, Li-Hua, Ma, Shanshan, Sutkeviciute, Ieva, Shen, Dan-Dan, Zhou, X Edward, de Waal, Parker W, Li, Chen-Yao, Kang, Yanyong, Clark, Lisa J, Jean-Alphonse, Frederic G, White, Alex D, Yang, Dehua, Dai, Antao, Cai, Xiaoqing, Chen, Jian, Li, Cong, Jiang, Yi, Watanabe, Tomoyuki, Gardella, Thomas J, Melcher, Karsten, Wang, Ming-Wei, Vilardaga, Jean-Pierre, Xu, H Eric, Zhang, Yan

Volltext

Structural biology of G protein‐coupled receptor signaling complexes von Edward Zhou, X., Melcher, Karsten, Eric Xu, H.

Volltext

A complex structure of arrestin-2 bound to a G protein-coupled receptor von Yin, Wanchao, Li, Zhihai, Jin, Mingliang, Yin, Yu-Ling, de Waal, Parker W., Pal, Kuntal, Yin, Yanting, Gao, Xiang, He, Yuanzheng, Gao, Jing, Wang, Xiaoxi, Zhang, Yan, Zhou, Hu, Melcher, Karsten, Jiang, Yi, Cong, Yao, Edward Zhou, X., Yu, Xuekui, Eric Xu, H.

Volltext

Structural basis of leukotriene B4 receptor 1 activation von Wang, Na, He, Xinheng, Zhao, Jing, Jiang, Hualiang, Cheng, Xi, Xia, Yu, Eric Xu, H., He, Yuanzheng

Volltext

Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor von Wang, Yue, Guo, Shimeng, Zhuang, Youwen, Yun, Ying, Xu, Peiyu, He, Xinheng, Guo, Jia, Yin, Wanchao, Xu, H. Eric, Xie, Xin, Jiang, Yi

Volltext

Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors von Zhao, Fenghui, Zhou, Qingtong, Cong, Zhaotong, Hang, Kaini, Zou, Xinyu, Zhang, Chao, Chen, Yan, Dai, Antao, Liang, Anyi, Ming, Qianqian, Wang, Mu, Chen, Li-Nan, Xu, Peiyu, Chang, Rulve, Feng, Wenbo, Xia, Tian, Zhang, Yan, Wu, Beili, Yang, Dehua, Zhao, Lihua, Xu, H. Eric, Wang, Ming-Wei

Volltext

Structure and Physiological Regulation of AMPK von Yan, Yan, Zhou, X Edward, Xu, H Eric, Melcher, Karsten

Volltext

Structural insights into the peptide selectivity and activation of human neuromedin U receptors von You, Chongzhao, Zhang, Yumu, Xu, Peiyu, Huang, Sijie, Yin, Wanchao, Eric Xu, H., Jiang, Yi

Volltext

Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex von Xing, Changrui, Zhuang, Youwen, Xu, Ting-Hai, Feng, Zhiwei, Zhou, X. Edward, Chen, Maozi, Wang, Lei, Meng, Xing, Xue, Ying, Wang, Junmei, Liu, Heng, McGuire, Terence Francis, Zhao, Gongpu, Melcher, Karsten, Zhang, Cheng, Xu, H. Eric, Xie, Xiang-Qun

Volltext

Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors von Duan, Jia, Shen, Dan-Dan, Zhao, Tingting, Guo, Shimeng, He, Xinheng, Yin, Wanchao, Xu, Peiyu, Ji, Yujie, Chen, Li-Nan, Liu, Jinyu, Zhang, Huibing, Liu, Qiufeng, Shi, Yi, Cheng, Xi, Jiang, Hualiang, Eric Xu, H., Zhang, Yan, Xie, Xin, Jiang, Yi

Volltext

Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2 von Zhuang, Youwen, Wang, Lei, Guo, Jia, Sun, Dapeng, Wang, Yue, Liu, Weiyi, Xu, H. Eric, Zhang, Cheng

Volltext

Androgen receptor： structure, role in prostate cancer and drug discovery von Tan, MH Eileen, Li, Jun, Xu, H Eric, Melcher, Karsten, Yong, Eu-leong

Volltext

Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2 von Xie, Yuanchao, Yin, Wanchao, Zhang, Yumin, Shang, Weijuan, Wang, Zhen, Luan, Xiaodong, Tian, Guanghui, Aisa, Haji A., Xu, Yechun, Xiao, Gengfu, Li, Jia, Jiang, Hualiang, Zhang, Shuyang, Zhang, Leike, Xu, H. Eric, Shen, Jingshan

Volltext

MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function von Fu, Ting, Seok, Sunmi, Choi, Sunge, Huang, Zhang, Suino-Powell, Kelly, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim

Volltext

Structural basis for the tethered peptide activation of adhesion GPCRs von Ping, Yu-Qi, Xiao, Peng, Yang, Fan, Zhao, Ru-Jia, Guo, Sheng-Chao, Yan, Xu, Wu, Xiang, Zhang, Chao, Lu, Yan, Zhao, Fenghui, Zhou, Fulai, Xi, Yue-Tong, Yin, Wanchao, Liu, Feng-Zhen, He, Dong-Fang, Zhang, Dao-Lai, Zhu, Zhong-Liang, Jiang, Yi, Du, Lutao, Feng, Shi-Qing, Schöneberg, Torsten, Liebscher, Ines, Xu, H. Eric, Sun, Jin-Peng

Volltext