GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade von Gargett, Tessa, Yu, Wenbo, Dotti, Gianpietro, Yvon, Eric S, Christo, Susan N, Hayball, John D, Lewis, Ian D, Brenner, Malcolm K, Brown, Michael P

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Cord blood natural killer cells expressing a dominant negative TGF-β receptor: Implications for adoptive immunotherapy for glioblastoma von Yvon, Eric S, Burga, Rachel, Powell, Allison, Cruz, Conrad R, Fernandes, Rohan, Barese, Cecilia, Nguyen, Tuongvan, Abdel-Baki, Mohamed S, Bollard, Catherine M

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Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD von Khoder, Ahmad, Sarvaria, Anushruti, Alsuliman, Abdullah, Chew, Claude, Sekine, Takuya, Cooper, Nichola, Mielke, Stephan, de Lavallade, Hugues, Muftuoglu, Muharrem, Fernandez Curbelo, Irina, Liu, Enli, Muraro, Paolo A., Alousi, Amin, Stringaris, Kate, Parmar, Simrit, Shah, Nina, Shaim, Hila, Yvon, Eric, Molldrem, Jeffrey, Rouce, Rayne, Champlin, Richard, McNiece, Ian, Mauri, Claudia, Shpall, Elizabeth J., Rezvani, Katayoun

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Medulloblastoma rendered susceptible to NK-cell attack by TGFβ neutralization von Powell, Allison B, Yadavilli, Sridevi, Saunders, Devin, Van Pelt, Stacey, Chorvinsky, Elizabeth, Burga, Rachel A, Albihani, Shuroug, Hanley, Patrick J, Xu, Zhenhua, Pei, Yanxin, Yvon, Eric S, Hwang, Eugene I, Bollard, Catherine M, Nazarian, Javad, Cruz, Conrad Russell Y

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CD137 agonist potentiates the abscopal efficacy of nanoparticle-based photothermal therapy for melanoma von Balakrishnan, Preethi Bala, Ledezma, Debbie K., Cano-Mejia, Juliana, Andricovich, Jaclyn, Palmer, Erica, Patel, Vishal A., Latham, Patricia S., Yvon, Eric S., Villagra, Alejandro, Fernandes, Rohan, Sweeney, Elizabeth E.

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Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity von Shah, Nina, Martin-Antonio, Beatriz, Yang, Hong, Ku, Stephanie, Lee, Dean A, Cooper, Laurence J N, Decker, William K, Li, Sufang, Robinson, Simon N, Sekine, Takuya, Parmar, Simrit, Gribben, John, Wang, Michael, Rezvani, Katy, Yvon, Eric, Najjar, Amer, Burks, Jared, Kaur, Indreshpal, Champlin, Richard E, Bollard, Catherine M, Shpall, Elizabeth J

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RNA polymerase II pausing factor NELF in CD8+ T cells promotes antitumor immunity von Wu, Bogang, Zhang, Xiaowen, Chiang, Huai-Chin, Pan, Haihui, Yuan, Bin, Mitra, Payal, Qi, Leilei, Simonyan, Hayk, Young, Colin N., Yvon, Eric, Hu, Yanfen, Zhang, Nu, Li, Rong

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BRAF and MEK inhibition variably affect GD2-specific chimeric antigen receptor (CAR) T-cell function in vitro von Gargett, Tessa, Fraser, Cara K, Dotti, Gianpietro, Yvon, Eric S, Brown, Michael P

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Novel TCR-like CAR-T cells targeting an HLA∗0201-restricted SSX2 epitope display strong activity against acute myeloid leukemia von Raskin, Scott, Van Pelt, Stacey, Toner, Keri, Balakrishnan, Preethi Bala, Dave, Hema, Bollard, Catherine M., Yvon, Eric

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Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells von YVON, Eric, DEL VECCHIO, Michele, SAVOLDO, Barbara, HOYOS, Valentina, DUTOUR, Aurélie, ANICHINI, Andrea, DOTTI, Gianpietro, BRENNER, Malcolm K

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Co-transducing B7H3 CAR-NK cells with the DNR preserves their cytolytic function against GBM in the presence of exogenous TGF-β von Chaudhry, Kajal, Geiger, Ashley, Dowlati, Ehsan, Lang, Haili, Sohai, Danielle K., Hwang, Eugene I., Lazarski, Christopher A., Yvon, Eric, Holdhoff, Matthias, Jones, Richard, Savoldo, Barbara, Cruz, Conrad Russell Y., Bollard, Catherine M.

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Improving efficacy of cancer immunotherapy by genetic modification of natural killer cells von Burga, Rachel A, Nguyen, Tuongvan, Zulovich, Jane, Madonna, Sarah, Ylisastigui, Loyda, Fernandes, Rohan, Yvon, Eric

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Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease von Cavazzana-Calvo, Marina, Hacein-Bey, Salima, Geneviève de Saint Basile, Gross, Fabian, Yvon, Eric, Nusbaum, Patrick, Selz, Françoise, Hue, Christophe, Certain, Stéphanie, Casanova, Jean-Laurent, Bousso, Philippe, Le Deist, Françoise, Fischer, Alain

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An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies von Ramos, Carlos Almeida, Asgari, Zahra, Liu, Enli, Yvon, Eric, Heslop, Helen E., Rooney, Clio M., Brenner, Malcolm K., Dotti, Gianpietro

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Gene Modification of Human Natural Killer Cells Using a Retroviral Vector von Kellner, Joshua N., Cruz, Conrad R., Bollard, Catherine M., Yvon, Eric S.

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Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells von Yvon, Eric S., Vigouroux, Stephane, Rousseau, Raphael F., Biagi, Ettore, Amrolia, Persis, Dotti, Gianpietro, Wagner, Hans-Joachim, Brenner, Malcolm K.

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All-in-one processing of heterogeneous human cell grafts for gene and cell therapy von Lukianova-Hleb, Ekaterina Y, Yvon, Eric S, Shpall, Elizabeth J, Lapotko, Dmitri O

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Responses to Human CD40 Ligand/Human Interleukin-2 Autologous Cell Vaccine in Patients with B-Cell Chronic Lymphocytic Leukemia von BIAGI, Ettore, ROUSSEAU, Raphael, CARRUM, George, RICE, Lawrence, ANDREEFF, Michael, POPAT, Uday, BRENNER, Malcolm, YVON, Eric, SCHWARTZ, Mary, DOTTI, Gianpietro, FOSTER, Aaron, HAVLIK-COOPER, Diana, GRILLEY, Bambi, GEE, Adrian, BAKER, Kelty

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Cord blood: a promising source of allogeneic natural killer cells for immunotherapy von Shaim, Hila, Yvon, Eric

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Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes von Vigouroux, Stéphane, Yvon, Eric, Wagner, Hans-Joachim, Biagi, Ettore, Dotti, Gianpietro, Sili, Uluhan, Lira, Cecilia, Rooney, Cliona M, Brenner, Malcolm K

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