Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation von Olson, Calla M, Jiang, Baishan, Erb, Michael A, Liang, Yanke, Doctor, Zainab M, Zhang, Zinan, Zhang, Tinghu, Kwiatkowski, Nicholas, Boukhali, Myriam, Green, Jennifer L, Haas, Wilhelm, Nomanbhoy, Tyzoon, Fischer, Eric S, Young, Richard A, Bradner, James E, Winter, Georg E, Gray, Nathanael S

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BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 Recruitment von Winter, Georg E., Mayer, Andreas, Buckley, Dennis L., Erb, Michael A., Roderick, Justine E., Vittori, Sarah, Reyes, Jaime M., di Iulio, Julia, Souza, Amanda, Ott, Christopher J., Roberts, Justin M., Zeid, Rhamy, Scott, Thomas G., Paulk, Joshiawa, Lachance, Kate, Olson, Calla M., Dastjerdi, Shiva, Bauer, Sophie, Lin, Charles Y., Gray, Nathanael S., Kelliher, Michelle A., Churchman, L. Stirling, Bradner, James E.

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Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders von Ishoey, Mette, Chorn, Someth, Singh, Natesh, Jaeger, Martin G, Brand, Matthias, Paulk, Joshiawa, Bauer, Sophie, Erb, Michael A, Parapatics, Katja, Müller, André C, Bennett, Keiryn L, Ecker, Gerhard F, Bradner, James E, Winter, Georg E

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Small-molecule tools for YEATS domain proteins von Erb, Michael A

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Cell-Based Ligand Discovery for the ENL YEATS Domain von Asiaban, Joshua N, Milosevich, Natalia, Chen, Emily, Bishop, Timothy R, Wang, Justin, Zhang, Yuxiang, Ackerman, Christopher J, Hampton, Eric N, Young, Travis S, Hull, Mitchell V, Cravatt, Benjamin F, Erb, Michael A

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Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia von Garnar-Wortzel, Leopold, Bishop, Timothy R, Kitamura, Seiya, Milosevich, Natalia, Asiaban, Joshua N, Zhang, Xiaoyu, Zheng, Qinheng, Chen, Emily, Ramos, Anissa R, Ackerman, Christopher J, Hampton, Eric N, Chatterjee, Arnab K, Young, Travis S, Hull, Mitchell V, Sharpless, K. Barry, Cravatt, Benjamin F, Wolan, Dennis W, Erb, Michael A

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Processing for destruction von Erb, Michael A.

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The dTAG system for immediate and target-specific protein degradation von Nabet, Behnam, Roberts, Justin M., Buckley, Dennis L., Paulk, Joshiawa, Dastjerdi, Shiva, Yang, Annan, Leggett, Alan L., Erb, Michael A., Lawlor, Matthew A., Souza, Amanda, Scott, Thomas G., Vittori, Sarah, Perry, Jennifer A., Qi, Jun, Winter, Georg E., Wong, Kwok-Kin, Gray, Nathanael S., Bradner, James E.

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ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia von Wan, Liling, Wen, Hong, Li, Yuanyuan, Lyu, Jie, Xi, Yuanxin, Hoshii, Takayuki, Joseph, Julia K., Wang, Xiaolu, Loh, Yong-Hwee E., Erb, Michael A., Souza, Amanda L., Bradner, James E., Shen, Li, Li, Wei, Li, Haitao, Allis, C. David, Armstrong, Scott A., Shi, Xiaobing

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Transcription control by the ENL YEATS domain in acute leukaemia von Erb, Michael A., Scott, Thomas G., Li, Bin E., Xie, Huafeng, Paulk, Joshiawa, Seo, Hyuk-Soo, Souza, Amanda, Roberts, Justin M., Dastjerdi, Shiva, Buckley, Dennis L., Sanjana, Neville E., Shalem, Ophir, Nabet, Behnam, Zeid, Rhamy, Offei-Addo, Nana K., Dhe-Paganon, Sirano, Zhang, Feng, Orkin, Stuart H., Winter, Georg E., Bradner, James E.

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Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma von Zeid, Rhamy, Lawlor, Matthew A., Poon, Evon, Reyes, Jaime M., Fulciniti, Mariateresa, Lopez, Michael A., Scott, Thomas G., Nabet, Behnam, Erb, Michael A., Winter, Georg E., Jacobson, Zoe, Polaski, Donald R., Karlin, Kristen L., Hirsch, Rachel A., Munshi, Nikhil P., Westbrook, Thomas F., Chesler, Louis, Lin, Charles Y., Bradner, James E.

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Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands von Gechijian, Lara N., Buckley, Dennis L., Lawlor, Matthew A., Reyes, Jaime M., Paulk, Joshiawa, Ott, Christopher J., Winter, Georg E., Erb, Michael A., Scott, Thomas G., Xu, Mousheng, Seo, Hyuk-Soo, Dhe-Paganon, Sirano, Kwiatkowski, Nicholas P., Perry, Jennifer A., Qi, Jun, Gray, Nathanael S., Bradner, James E.

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Pharmacological Modulation of Transcriptional Coregulators in Cancer von Bishop, Timothy R., Zhang, Yuxiang, Erb, Michael A.

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A short ORF-encoded transcriptional regulator von Koh, Minseob, Ahmad, Insha, Ko, Yeonjin, Zhang, Yuxiang, Martinez, Thomas F., Diedrich, Jolene K., Chu, Qian, Moresco, James J., Erb, Michael A., Saghatelian, Alan, Schultz, Peter G., Bollong, Michael J.

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SuFEx-based chemical diversification for the systematic discovery of CRBN molecular glues von Carter, Trever R., Milosevich, Natalia, Dada, Lucas, Shaum, James B., Barry Sharpless, K., Kitamura, Seiya, Erb, Michael A.

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Acetyl-CoA biosynthesis drives resistance to histone acetyltransferase inhibition von Bishop, Timothy R., Subramanian, Chitra, Bilotta, Eric M., Garnar-Wortzel, Leopold, Ramos, Anissa R., Zhang, Yuxiang, Asiaban, Joshua N., Ott, Christopher J., Rock, Charles O., Erb, Michael A.

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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities von Zhang, Yuxiang, Remillard, David, Onubogu, Ugoma, Karakyriakou, Barbara, Asiaban, Joshua N., Ramos, Anissa R., Bowland, Kirsten, Bishop, Timothy R., Barta, Paige A., Nance, Stephanie, Durbin, Adam D., Ott, Christopher J., Janiszewska, Michalina, Cravatt, Benjamin F., Erb, Michael A.

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Inherited blood cancer predisposition through altered transcription elongation von Zhao, Jiawei, Cato, Liam D., Arora, Uma P., Bao, Erik L., Bryant, Samuel C., Williams, Nicholas, Jia, Yuemeng, Goldman, Seth R., Nangalia, Jyoti, Erb, Michael A., Vos, Seychelle M., Armstrong, Scott A., Sankaran, Vijay G.

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Redirecting the pioneering function of FOXA1 with covalent small molecules von Won, Sang Joon, Zhang, Yuxiang, Reinhardt, Christopher J., Hargis, Lauren M., MacRae, Nicole S., DeMeester, Kristen E., Njomen, Evert, Remsberg, Jarrett R., Melillo, Bruno, Cravatt, Benjamin F., Erb, Michael A.

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Functional Investigations of p53 Acetylation Enabled by Heterobifunctional Molecules von Chen, Li-Yun, Singha Roy, Soumya Jyoti, Jadhav, Appaso M., Wang, Wesley W., Chen, Pei-Hsin, Bishop, Timothy, Erb, Michael A., Parker, Christopher G.

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