Use of N-Fmoc amino acid chlorides and activated 2-(fluorenylmethoxy)-5(4H)-oxazolones in solid-phase peptide synthesis. Efficient syntheses of highly N-alkylated cyclic hexapeptid... von Perlow, Debra S, Erb, Jill M, Gould, Norman P, Tung, Roger D, Freidinger, Roger M, Williams, Peter D, Veber, Daniel F

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1-(((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo[2.2.1]heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperazine (L-368,899): An Orally Bioavailable, Non-... von Williams, Peter D, Anderson, Paul S, Ball, Richard G, Bock, Mark G, Carroll, LeighAnne, Chiu, Shuet-Hing Lee, Clineschmidt, Bradley V, Culberson, J. Chris, Erb, Jill M

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Inhibition of steroid 5.alpha.-reductase by unsaturated 3-carboxy steroids von Holt, Dennis A, Levy, Mark A, Oh, Hye Ja, Erb, Jill M, Heaslip, Julie I, Brandt, Martin, Lan-Hargest, Hsuan Yin, Metcalf, Brian W

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Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product von Williams, Peter D, Bock, Mark G, Tung, Roger D, Garsky, Victor M, Perlow, Debra S, Erb, Jill M, Lundell, G. F, Gould, Norman P, Whitter, Willie L

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1-[1-[4-[(N-Acetyl-4-piperidinyl)oxy]-2- methoxybenzoyl]piperidin-4-yl]-4H-3,1- benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist von Williams, Peter D, Clineschmidt, Bradley V, Erb, Jill M, Freidinger, Roger M, Guidotti, Maribeth T, Lis, Edward V, Pawluczyk, Joseph M, Pettibone, Douglas J, Reiss, Duane R

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Development of Orally Active Oxytocin Antagonists:  Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d... von Bell, Ian M, Erb, Jill M, Freidinger, Roger M, Gallicchio, Steven N, Guare, James P, Guidotti, Maribeth T, Halpin, Rita A, Hobbs, Doug W, Homnick, Carl F, Kuo, Michelle S, Lis, Edward V, Mathre, David J, Michelson, Stuart R, Pawluczyk, Joseph M, Pettibone, Douglas J, Reiss, Duane R, Vickers, Stanley, Williams, Peter D, Woyden, Carla J

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Steroidal A ring aryl carboxylic acids: a new class of steroid 5.alpha.-reductase inhibitors von Holt, Dennis A, Levy, Mark A, Ladd, David L, Oh, Hye Ja, Erb, Jill M, Heaslip, Julie I, Brandt, Martin, Metcalf, Brian W

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1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist von WILLIAMS, P. D, CLINESCHMIDT, B. V, WOYDEN, C. J, ERB, J. M, FREIDINGER, R. M, GUIDOTTI, M. T, LIS, E. V, PAWLUCZYK, J. M, PETTIBONE, D. J, REISS, D. R, VEBER, D. F

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Palladium-catalyzed phosphorylation of alkenyl triflates von Holt, Dennis A., Erb, Jill M.

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Inhibition of steroid 5α-reductase by unsaturated 3-carboxysteroids von HOLT, D. A, LEVY, M. A, HYE-JA OH, ERB, J. M, HEASLIP, J. I, BRANDT, M, HSUAN-YIN LAN-HARGEST, METCALF, B. W

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Steroidal a ring aryl carboxylic acids : a new class of steroid 5α-reductase inhibitors von HOLT, D. A, LEVY, M. A, LADD, D. L, HYE-JA OH, ERB, J. M, HEASLIP, J. I, BRANDT, M, METCALF, B. W

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Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists von Nerenberg, Jennie B., Erb, Jill M., Thompson, Wayne J., Lee, Hee-Yoon, Guare, James P., Munson, Peter M., Bergman, Jeffrey M., Huff, Joel R., Broten, Theodore P., Chang, Raymond S.L., Chen, Tsing B., O'Malley, Stacey, Schorn, Terry W., Scott, Ann L.

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4-Oxospiro[benzopyran-2,4′-piperidines] as selective α1a-adrenergic receptor antagonists von Nerenberg, Jennie B., Erb, Jill M., Bergman, Jeffrey M., O'Malley, Stacey, Chang, Raymond S.L., Scott, Ann L., Broten, Theodore P., Bock, Mark G.

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Nanomolar-affinity, non-peptide oxytocin receptor antagonists von Evans, Ben E, Lundell, George F, Gilbert, Kevin F, Bock, Mark G, Rittle, Kenneth E, Carroll, Leigh Anne, Williams, Peter D, Pawluczyk, Joseph M, Leighton, James L

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Conformationally constrained o-tolylpiperazine camphorsulfonamide oxytocin antagonists. Structural modifications that provide high receptor affinity and suggest a bioactive conform... von Williams, Peter D., Ball, Richard G., Clineschmidt, Bradley V., Culberson, J.Chris, Erb, Jill M., Freidinger, Roger M., Pawluczyk, Joseph M., Perlow, Debra S., Pettibone, Douglas J., Veber, Daniel F.

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Potent inhibition of human steroid 5α-reductase (EC 1.3.1.30) by 3-androstene-3-carboxylic acids von Metcalf, Brian W., Holt, Dennis A., Levy, Mark A., Erb, Jill M., Heaslip, Julie I., Brandt, Martin, Oh, Hye-Ja

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3-Phosphinic acid and 3-phosphonic acid steroids as inhibitors of steroid 5α-reductase: Species comparison and mechanistic studies von Levy, Mark A., Metcalf, Brian W., Brandt, Martin, Erb, Jill M., Oh, Hye-Ja, Heaslip, Julie I., Yen, Hwa-Kwo, Rozamus, Leonard W., Holt, Dennis A.

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SUBSTITUTED AMINE DERIVATIVES OF PIPERAZINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS von VEBER, DANIEL F, WILLIAMS, PETER D, ERB, JILL M

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Substituted amine derivatives of piperazinylcamphorsulfonyl oxytocin antagonists von VEBER, DANIEL F, WILLIAMS, PETER D, ERB, JILL M

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SUBSTITUTED AMINE DERIVATIVES OF PIPERIZINYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS von VEBER, DANIEL F, WILLIAMS, PETER D, ERB, JILL M

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