Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport von McCauley, Heather A., Matthis, Andrea L., Enriquez, Jacob R., Nichol, Jonah T., Sanchez, J. Guillermo, Stone, William J., Sundaram, Nambirajan, Helmrath, Michael A., Montrose, Marshall H., Aihara, Eitaro, Wells, James M.

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Deriving functional human enteroendocrine cells from pluripotent stem cells von Sinagoga, Katie L, McCauley, Heather A, Múnera, Jorge O, Reynolds, Nichole A, Enriquez, Jacob R, Watson, Carey, Yang, Hsiu-Chiung, Helmrath, Michael A, Wells, James M

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A dietary change to a high-fat diet initiates a rapid adaptation of the intestine von Enriquez, Jacob R., McCauley, Heather A., Zhang, Kevin X., Sanchez, J. Guillermo, Kalin, Gregory T., Lang, Richard A., Wells, James M.

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Using Human Induced Pluripotent Stem Cell-Derived Organoids to Identify New Pathologies in Patients With PDX1 Mutations von Krishnamurthy, Mansa, Kechele, Daniel O, Broda, Taylor, Zhang, Xinghao, Enriquez, Jacob R, McCauley, Heather A, Sanchez, J Guillermo, McCracken, Kyle, Palermo, Joseph, Bernieh, Anas, Collins, Margaret H, Thomas, Inas H, Neef, Haley C, Heider, Amer, Dauber, Andrew, Wells, James M

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RFX6 regulates human intestinal patterning and function upstream of PDX1 von Sanchez, J Guillermo, Rankin, Scott, Paul, Emily, McCauley, Heather A, Kechele, Daniel O, Enriquez, Jacob R, Jones, Nana-Hawa, Greeley, Siri A W, Letourneau-Freiberg, Lisa, Zorn, Aaron M, Krishnamurthy, Mansa, Wells, James M

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Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon von Múnera, Jorge O, Kechele, Daniel O, Bouffi, Carine, Qu, Na, Jing, Ran, Maity, Pritiprasanna, Enriquez, Jacob R, Han, Lu, Campbell, Ian, Mahe, Maxime M, McCauley, Heather A, Zhang, Xinghao, Sundaram, Nambirajan, Hudson, Jonathan R, Zarsozo-Lacoste, Adrian, Pradhan, Suman, Tominaga, Kentaro, Sanchez, J Guillermo, Weiss, Alison A, Chatuvedi, Praneet, Spence, Jason R, Hachimi, Mariam, North, Trista, Daley, George Q, Mayhew, Christopher N, Hu, Yueh-Chiang, Takebe, Takanori, Helmrath, Michael A, Wells, James M

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RFX6 regulates human intestinal patterning and function upstream of PDX1 von Sanchez, J Guillermo, Rankin, Scott, Paul, Emily, McCauley, Heather A, Kechele, Daniel O, Enriquez, Jacob R, Jones, Nana-Hawa, Greeley, Siri A W, Letourneau-Frieberg, Lisa, Zorn, Aaron M, Krishnamurthy, Mansa, Wells, James M

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Inhibition of the eukaryotic initiation factor-2α kinase PERK decreases risk of autoimmune diabetes in mice von Muralidharan, Charanya, Huang, Fei, Enriquez, Jacob R, Wang, Jiayi E, Nelson, Jennifer B, Nargis, Titli, May, Sarah C, Chakraborty, Advaita, Figatner, Kayla T, Navitskaya, Svetlana, Anderson, Cara M, Calvo, Veronica, Surguladze, David, Mulvihill, Mark J, Yi, Xiaoyan, Sarkar, Soumyadeep, Oakes, Scott A, Webb-Robertson, Bobbie-Jo M, Sims, Emily K, Staschke, Kirk A, Eizirik, Decio L, Nakayasu, Ernesto S, Stokes, Michael E, Tersey, Sarah A, Mirmira, Raghavendra G

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Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to Nutrients von McCauley, Heather A., Riedman, Anne Marie, Enriquez, Jacob R., Zhang, Xinghao, Watanabe-Chailland, Miki, Sanchez, J. Guillermo, Kechele, Daniel O., Paul, Emily F., Riley, Kayle, Burger, Courtney, Lang, Richard A., Wells, James M.

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Deriving human intestinal organoids with functional tissue-resident macrophages all from pluripotent stem cells von Tominaga, Kentaro, Kechele, Daniel O, Sanchez, J Guillermo, Vales, Simon, Jurickova, Ingrid, Roman, Lizza, Asai, Akihiro, Enriquez, Jacob R, McCauley, Heather A, Kishimoto, Keishi, Iwasawa, Kentaro, Singh, Akaljot, Horio, Yuko, Múnera, Jorge O, Takebe, Takanori, Zorn, Aaron M, Helmrath, Michael A, Denson, Lee A, Wells, James M

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Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes von Sims, Emily K, Kulkarni, Abhishek, Hull, Audrey, Woerner, Stephanie E, Cabrera, Susanne, Mastrandrea, Lucy D, Hammoud, Batoul, Sarkar, Soumyadeep, Nakayasu, Ernesto S, Mastracci, Teresa L, Perkins, Susan M, Ouyang, Fangqian, Webb-Robertson, Bobbie-Jo, Enriquez, Jacob R, Tersey, Sarah A, Evans-Molina, Carmella, Long, S Alice, Blanchfield, Lori, Gerner, Eugene W, Mirmira, Raghavendra G, DiMeglio, Linda A

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12-Lipoxygenase inhibition delays onset of autoimmune diabetes in human gene replacement mice von Nargis, Titli, Muralidharan, Charanya, Enriquez, Jacob R, Wang, Jiayi E, Kaylan, Kerim B, Chakraborty, Advaita, Pratuangtham, Sarida, Figatner, Kayla, Nelson, Jennifer B, May, Sarah C, Nadler, Jerry L, Boxer, Matthew B, Maloney, David J, Tersey, Sarah A, Mirmira, Raghavendra G

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Sex-based differences in odds of motor vehicle crash injury outcomes von Craig, Matthew J, Liu, Cejun, Zhang, Fan, Enriquez, Jacob

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GENERATION OF HUMAN INTESTINAL ORGANOIDS CONTAINING TISSUE-RESIDENT IMMUNE CELLS von Tominaga, Kentaro, Kechele, Dan, Sanchez, Guillermo, McCauley, Heather, Enriquez, Jacob, Vales, Simon, Jurickova, Ingrid, Denson, Lee, Takebe, Takanori, Helmrath, Michael, Zorn, Aaron, Wells, James

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Vegf signaling promotes vascular endothelial differentiation by modulating etv2 expression von Casie Chetty, Satish, Rost, Megan S., Enriquez, Jacob Ryan, Schumacher, Jennifer A., Baltrunaite, Kristina, Rossi, Andrea, Stainier, Didier Y.R., Sumanas, Saulius

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GENERATION OF HUMAN INTESTINAL ORGANOIDS CONTAINING TISSUE-RESIDENT IMMUNE CELLS von Tominaga, Kentaro, Kechele, Dan, Sanchez, Guillermo, McCauley, Heather, Enriquez, Jacob, Vales, Simon, Jurickova, Ingrid, Denson, Lee, Takebe, Takanori, Helmrath, Michael, Zorn, Aaron, Wells, James

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Inhibition of the eukaryotic initiation factor-2[alpha] kinase PERK decreases risk of autoimmune diabetes in mice von Muralidharan, Charanya, Huang, Fei, Enriquez, Jacob R, Wang, Jiayi E, Nelson, Jennifer B, Nargis, Titli, May, Sarah C, Chakraborty, Advaita, Figatner, Kayla T, Navitskaya, Svetlana, Anderson, Cara M, Calvo, Veronica, Surguladze, David, Mulvihill, Mark J, Yi, Xiaoyan, Sarkar, Soumyadeep, Oakes, Scott A, Webb-Robertson, Bobbie-Jo M, Sims, Emily K, Staschke, Kirk A, Eizirik, Decio L, Nakayasu, Ernesto S, Stokes, Michael E, Tersey, Sarah A, Mirmira, Raghavendra G

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FRI613 Sex Differences In Human Islet Transcriptional Responses To Inflammation von Webster, Kierstin L, Wu, Wenting, Webb-Robertson, Bobbie-Jo, Nakayasu, Ernesto, Sarkar, Soumyadeep, Evans-Molina, Carmella, Tersey, Sarah A, Enriquez, Jacob, Hammes, Stephen R, Mirmira, Raghavendra G

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OR12-01 Blocking The Maladaptive Integrated Stress Response Increases Immunosuppressive PD-L1 In Pancreatic β-Cells von Muralidharan, Charanya, Huiping huang, Fei, May, Sarah C, Enriquez, Jacob, Nelson, Jennifer B, Wang, Eugenia, Chakraborthy, Advaita, Figatner, Kayla T, Navitskaya, Svetlana N, Tersey, Sarah A, Mirmira, Raghavendra G

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Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to NutrientsSummary von Heather A. McCauley, Anne Marie Riedman, Jacob R. Enriquez, Xinghao Zhang, Miki Watanabe-Chailland, J. Guillermo Sanchez, Daniel O. Kechele, Emily F. Paul, Kayle Riley, Courtney Burger, Richard A. Lang, James M. Wells

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