X-ray absorption spectroscopic characterization of the diferric-peroxo intermediate of human deoxyhypusine hydroxylase in the presence of its substrate eIF5a von Jasniewski, Andrew J., Engstrom, Lisa M., Vu, Van V., Park, Myung Hee, Que, Lawrence

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A Zinc Linchpin Motif in the MUTYH Glycosylase Interdomain Connector Is Required for Efficient Repair of DNA Damage von Engstrom, Lisa M, Brinkmeyer, Megan K, Ha, Yang, Raetz, Alan G, Hedman, Britt, Hodgson, Keith O, Solomon, Edward I, David, Sheila S

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An Iron–Sulfur Cluster Loop Motif in the Archaeoglobus fulgidus Uracil–DNA Glycosylase Mediates Efficient Uracil Recognition and Removal von Engstrom, Lisa M, Partington, Olga A, David, Sheila S

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A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study) von Mcgowan, Ian, Cranston, Ross D, Duffill, Kathryn, Siegel, Aaron, Engstrom, Jarret C, Nikiforov, Alexyi, Jacobson, Cindy, Rehman, Khaja K, Elliott, Julie, Khanukhova, Elena, Abebe, Kaleab, Mauck, Christine, Spiegel, Hans M L, Dezzutti, Charlene S, Rohan, Lisa C, Marzinke, Mark A, Hiruy, Hiwot, Hendrix, Craig W, Richardson-Harman, Nicola, Anton, Peter A

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Degradation in carbon stocks near tropical forest edges von Chaplin-Kramer, Rebecca, Ramler, Ivan, Sharp, Richard, Haddad, Nick M., Gerber, James S., West, Paul C., Mandle, Lisa, Engstrom, Peder, Baccini, Alessandro, Sim, Sarah, Mueller, Carina, King, Henry

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Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP-Deleted Cancers von Smith, Christopher R, Aranda, Ruth, Bobinski, Thomas P, Briere, David M, Burns, Aaron C, Christensen, James G, Clarine, Jeffery, Engstrom, Lars D, Gunn, Robin J, Ivetac, Anthony, Jean-Baptiste, Ronald, Ketcham, John M, Kobayashi, Masakazu, Kuehler, Jon, Kulyk, Svitlana, Lawson, J. David, Moya, Krystal, Olson, Peter, Rahbaek, Lisa, Thomas, Nicole C, Wang, Xiaolun, Waters, Laura M, Marx, Matthew A

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Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery von Hausenloy, Derek J., Barrabes, Jose A., Bøtker, Hans Erik, Davidson, Sean M., Di Lisa, Fabio, Downey, James, Engstrom, Thomas, Ferdinandy, Péter, Carbrera-Fuentes, Hector A., Heusch, Gerd, Ibanez, Borja, Iliodromitis, Efstathios K., Inserte, Javier, Jennings, Robert, Kalia, Neena, Kharbanda, Rajesh, Lecour, Sandrine, Marber, Michael, Miura, Tetsuji, Ovize, Michel, Perez-Pinzon, Miguel A., Piper, Hans Michael, Przyklenk, Karin, Schmidt, Michael Rahbek, Redington, Andrew, Ruiz-Meana, Marisol, Vilahur, Gemma, Vinten-Johansen, Jakob, Yellon, Derek M., Garcia-Dorado, David

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Searching for Atrial Fibrillation Poststroke: A White Paper of the AF-SCREEN International Collaboration von Schnabel, Renate B, Haeusler, Karl Georg, Healey, Jeffrey S, Freedman, Ben, Boriani, Giuseppe, Brachmann, Johannes, Brandes, Axel, Bustamante, Alejandro, Casadei, Barbara, Crijns, Harry J.G.M, Doehner, Wolfram, Engström, Gunnar, Fauchier, Laurent, Friberg, Leif, Gladstone, David J, Glotzer, Taya V, Goto, Shinya, Hankey, Graeme J, Harbison, Joseph A, Hobbs, F.D Richard, Johnson, Linda S.B, Kamel, Hooman, Kirchhof, Paulus, Korompoki, Eleni, Krieger, Derk W, Lip, Gregory Y.H, Løchen, Maja-Lisa, Mairesse, Georges H, Montaner, Joan, Neubeck, Lis, Ntaios, George, Piccini, Jonathan P, Potpara, Tatjana S, Quinn, Terence J, Reiffel, James A, Ribeiro, Antonio Luiz Pinho, Rienstra, Michiel, Rosenqvist, Mårten, Sakis, Themistoclakis, Sinner, Moritz F, Svendsen, Jesper Hastrup, Van Gelder, Isabelle C, Wachter, Rolf, Wijeratne, Tissa, Yan, Bernard

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Association of Cardiometabolic Multimorbidity With Mortality: The Emerging Risk Factors Collaboration von Di Angelantonio, Emanuele, Kaptoge, Stephen, Wormser, David, Willeit, Peter, Butterworth, Adam S., Bansal, Narinder, O'Keeffe, Linda M., Gao, Pei, Wood, Angela M., Burgess, Stephen, Freitag, Daniel F., Pennells, Lisa, Peters, Sanne A., Hart, Carole L., Haheim, Lise Lund, Gillum, Richard F., Nordestgaard, Borge G., Psaty, Bruce M., Yeap, Bu B., Knuiman, Matthew W., Nietert, Paul J., Kauhanen, Jussi, Salonen, Jukka T., Kuller, Lewis H., Simons, Leon A., van der Schouw, Yvonne T., Barrett-Connor, Elizabeth, Selmer, Randi, Crespo, Carlos J., Rodriguez, Beatriz, Verschuren, W. M. Monique, Salomaa, Veikko, Svärdsudd, Kurt, van der Harst, Pim, Bjorkelund, Cecilia, Wilhelmsen, Lars, Wallace, Robert B., Brenner, Hermann, Amouyel, Philippe, Barr, Elizabeth L. M., Iso, Hiroyasu, Onat, Altan, Trevisan, Maurizio, D'Agostino, Ralph B., Sr, Cooper, Cyrus, Kavousi, Maryam, Welin, Lennart, Roussel, Ronan, Hu, Frank B., Sato, Shinichi, Davidson, Karina W., Howard, Barbara V., Leening, Maarten, Rosengren, Annika, Dorr, Marcus, Deeg, Dorly J. H., Kiechl, Stefan, Stehouwer, Coen D. A., Nissinen, Aulikki, Giampaoli, Simona, Donfrancesco, Chiara, Kromhout, Daan, Price, Jackie F., Peters, Annette, Meade, Tom W., Casiglia, Edoardo, Lawlor, Debbie A., Gallacher, John, Nagel, Dorothea, Franco, Oscar H., Assmann, Gerd, Dagenais, Gilles R., Jukema, J. Wouter, Sundström, Johan, Woodward, Mark, Brunner, Eric J., Khaw, Kay-Tee, Wareham, Nicholas J., Whitsel, Eric A., Njolstad, Inger, Hedblad, Bo, Wassertheil-Smoller, Sylvia, Engstrom, Gunnar, Rosamond, Wayne D., Selvin, Elizabeth, Sattar, Naveed, Thompson, Simon G., Danesh, John

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Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein von Ketcham, John M., Harwood, Stephen J., Aranda, Ruth, Aloiau, Athenea N., Bobek, Briana M., Briere, David M., Burns, Aaron C., Caddell Haatveit, Kersti, Calinisan, Andrew, Clarine, Jeffery, Elliott, Adam, Engstrom, Lars D., Gunn, Robin J., Ivetac, Anthony, Jones, Benjamin, Kuehler, Jon, Lawson, J. David, Nguyen, Natalie, Parker, Cody, Pearson, Kelly E., Rahbaek, Lisa, Saechao, Barbara, Wang, Xiaolun, Waters, Anna, Waters, Laura, Watkins, Ashlee H., Olson, Peter, Smith, Christopher R., Christensen, James G., Marx, Matthew A.

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Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses von Sofianopoulou, Eleni, Kaptoge, Stephen K, Afzal, Shoaib, Jiang, Tao, Gill, Dipender, Gundersen, Thomas E, Bolton, Thomas R, Allara, Elias, Arnold, Matthew G, Mason, Amy M, Chung, Ryan, Pennells, Lisa A M, Shi, Fanchao, Sun, Luanluan, Willeit, Peter, Forouhi, Nita G, Langenberg, Claudia, Sharp, Stephen J, Panico, Salvatore, Engström, Gunnar, Melander, Olle, Tong, Tammy Y N, Perez-Cornago, Aurora, Norberg, Margareta, Johansson, Ingegerd, Katzke, Verena, Srour, Bernard, José Sánchez, María, Redondo-Sánchez, Daniel, Olsen, Anja, Dahm, Christina C, Overvad, Kim, Brustad, Magritt, Skeie, Guri, Moreno-Iribas, Conchi, Onland-Moret, N Charlotte, van der Schouw, Yvonne T, Tsilidis, Konstantinos K, Heath, Alicia K, Agnoli, Claudia, Krogh, Vittorio, de Boer, Ian H, Kobylecki, Camilla Jannie, Çolak, Yunus, Zittermann, Armin, Sundström, Johan, Welsh, Paul, Weiderpass, Elisabete, Aglago, Elom K, Ferrari, Pietro, Clarke, Robert, Boutron, Marie-Christine, Severi, Gianluca, MacDonald, Conor, Providencia, Rui, Masala, Giovanna, Zamora Ros, Raul, Boer, Jolanda, Verschuren, WM Monique, Cawthon, Peggy, Schierbeck, Louise L, Cooper, Cyrus, Schulze, Matthias B, Bergmann, Manuela M, Hannemann, Anke, Kiechl, Stefan, Brenner, Hermann, van Schoor, Natasja M, Albertorio, Juan R, Sacerdote, Carlotta, Linneberg, Allan, Kårhus, Line L, Huerta, José María, Imaz, Liher, Joergensen, Christel, Ben-Shlomo, Yoav, Lundqvist, Annamari, Gallacher, John, Sattar, Naveed, Wood, Angela M, Wareham, Nicholas J, Nordestgaard, Børge G, Di Angelantonio, Emanuele, Danesh, John, Butterworth, Adam S, Burgess, Stephen

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Swedish snus use is associated with mortality: a pooled analysis of eight prospective studies von Byhamre, Marja Lisa, Araghi, Marzieh, Alfredsson, Lars, Bellocco, Rino, Engström, Gunnar, Eriksson, Marie, Galanti, Maria Rosaria, Jansson, Jan-Håkan, Lager, Anton, Lundberg, Michael, Östergren, Per-Olof, Pedersen, Nancy L, Trolle Lagerros, Ylva, Ye, Weimin, Wennberg, Patrik, Magnusson, Cecilia

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The Florida Geriatric Head Trauma CT Clinical Decision Rule von Shih, Richard D., Alter, Scott M., Wells, Mike, Solano, Joshua J., Engstrom, Gabriella, Clayton, Lisa M., Hughes, Patrick G., Goldstein, Lara, Lottenberg, Lawrence, Ouslander, Joseph G.

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A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study) von McGowan, Ian M, Chawki, Sylvain, Hendrix, Craig W, Anton, Peter A, Marzinke, Mark A, Brand, Rhonda M, Engstrom, Jarret C, Rohan, Lisa C, Abebe, Kaleab Z, Richardson-Harman, Nicola, Siegel, Aaron, Reinhart, Alex, Steytler, John, Stall, Ronald, Spiegel, Hans, Chen, Beatrice, Achilles, Sharon L, Jacobson, Cindy E, Khanukova, Elena, Cranston, Ross D

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Alcohol use is associated with intracranial hemorrhage in older emergency department head trauma patients von Zirulnik, Alexander, Liu, Shan, Wells, Mike, Alter, Scott M., Engstrom, Gabriella, Solano, Joshua J., Clayton, Lisa M., Reiter, Mark, Hughes, Patrick G., Goldstein, Lara, Shih, Richard D.

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Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor von Hallin, Jill, Bowcut, Vickie, Calinisan, Andrew, Briere, David M., Hargis, Lauren, Engstrom, Lars D., Laguer, Jade, Medwid, James, Vanderpool, Darin, Lifset, Ella, Trinh, David, Hoffman, Natalie, Wang, Xiaolun, David Lawson, J., Gunn, Robin J., Smith, Christopher R., Thomas, Nicole C., Martinson, Matthew, Bergstrom, Alex, Sullivan, Francis, Bouhana, Karyn, Winski, Shannon, He, Leo, Fernandez-Banet, Julio, Pavlicek, Adam, Haling, Jacob R., Rahbaek, Lisa, Marx, Matthew A., Olson, Peter, Christensen, James G.

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Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin von Wong, John, Smith, Logan B., Magun, Eli A., Engstrom, Thomas, Kelley-Howard, Kirsten, Jandhyala, Dakshina M., Thorpe, Cheleste M., Magun, Bruce E., Wood, Lisa J.

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Low Incidence of Delayed Intracranial Hemorrhage in Geriatric Emergency Department Patients on Preinjury Anticoagulation Presenting with Blunt Head Trauma von Shih, Richard D., Alter, Scott M., Solano, Joshua J., Engstrom, Gabriella, Wells, Mike, Clayton, Lisa M., Hughes, Patrick G., Goldstein, Lara Nicole, Azar, Faris K., Ouslander, Joseph G.

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Risk Assessment of the Leachables’ Profile for Small-Molecule Pharmaceutical Drug Substances von Reddy, Rajarathnam E, Hu, Wenbin, Lowry, Brian R, Fogle, Jace L, Malick, Robert E, Erexson, Greg, Westerberg, John M, Carragher, Adelia L, Robinson, Emily E, Orihuela, Carlos A, Hillier, Michael C, Davis, Steven R, Kruk, Paul E, Ide, Nathan D, Mlinar, Laurie, Mulhern, Mathew M, Engstrom, Kenneth M, Chaaya, Elie, McKee, Laura A, Manning, Patrick E, Tirino, Pasquale, Joudioux, Roberta, Cornelio, Lisa

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Lack of patient and primary care physician follow-up in geriatric emergency department patients with head trauma from a fall von Shih, Richard D., Solano, Joshua J., Engstrom, Gabriella, Khazem, Maya, Clayton, Lisa M., Wells, Michael, Hughes, Patrick G., Posaw, Leila, Goldstein, Lara, Hennekens, Charles H., Ouslander, Joseph G., Alter, Scott M.

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