Chemical activation of the mechanotransduction channel Piezo1 von Syeda, Ruhma, Xu, Jie, Dubin, Adrienne E, Coste, Bertrand, Mathur, Jayanti, Huynh, Truc, Matzen, Jason, Lao, Jianmin, Tully, David C, Engels, Ingo H, Petrassi, H Michael, Schumacher, Andrew M, Montal, Mauricio, Bandell, Michael, Patapoutian, Ardem

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Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity von Ramadoss, Nitya S., Alumasa, John N., Cheng, Lin, Wang, Yu, Li, Sharon, Chambers, Benjamin S., Chang, Hoon, Chatterjee, Arnab K., Brinker, Achim, Engels, Ingo H., Keiler, Kenneth C.

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Synthetic lethal targeting of MYC by activation of the DR5 death receptor pathway von Wang, Yan, Engels, Ingo H, Knee, Deborah A, Nasoff, Marc, Deveraux, Quinn L, Quon, Kim C

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Identification of small molecule and genetic modulators of AON-induced dystrophin exon skipping by high-throughput screening von O'Leary, Debra A, Sharif, Orzala, Anderson, Paul, Tu, Buu, Welch, Genevieve, Zhou, Yingyao, Caldwell, Jeremy S, Engels, Ingo H, Brinker, Achim

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Caspase-2 Can Function Upstream of Bid Cleavage in the TRAIL Apoptosis Pathway von Wagner, Klaus W, Engels, Ingo H, Deveraux, Quinn L

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Apoptosis resistance of MCF-7 breast carcinoma cells to ionizing radiation is independent of p53 and cell cycle control but caused by the lack of Caspase-3 and a caffeine-inhibitab... von ESSMANN, Frank, ENGELS, Ingo H, TOTZKE, Gudrun, SCHULZE-OSTHOFF, Klaus, JÄNICKE, Reiner U

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity von Barretina, Jordi, Caponigro, Giordano, Stransky, Nicolas, Venkatesan, Kavitha, Margolin, Adam A., Kim, Sungjoon, Wilson, Christopher J., Lehár, Joseph, Kryukov, Gregory V., Sonkin, Dmitriy, Reddy, Anupama, Liu, Manway, Murray, Lauren, Berger, Michael F., Monahan, John E., Morais, Paula, Meltzer, Jodi, Korejwa, Adam, Jané-Valbuena, Judit, Mapa, Felipa A., Thibault, Joseph, Bric-Furlong, Eva, Raman, Pichai, Shipway, Aaron, Engels, Ingo H., Cheng, Jill, Yu, Guoying K., Yu, Jianjun, Aspesi, Peter, de Silva, Melanie, Jagtap, Kalpana, Jones, Michael D., Wang, Li, Hatton, Charles, Palescandolo, Emanuele, Gupta, Supriya, Mahan, Scott, Sougnez, Carrie, Onofrio, Robert C., Liefeld, Ted, MacConaill, Laura, Winckler, Wendy, Reich, Michael, Li, Nanxin, Mesirov, Jill P., Gabriel, Stacey B., Getz, Gad, Ardlie, Kristin, Chan, Vivien, Myer, Vic E., Weber, Barbara L., Porter, Jeff, Warmuth, Markus, Finan, Peter, Harris, Jennifer L., Meyerson, Matthew, Golub, Todd R., Morrissey, Michael P., Sellers, William R., Schlegel, Robert, Garraway, Levi A.

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Agonists of Proteinase-Activated Receptor-2 Stimulate Upregulation of Intercellular Cell Adhesion Molecule-1 in Primary Human Keratinocytes via Activation of NF-kappa B von Buddenkotte, Jörg, Stroh, Christopher, Engels, Ingo H., Moormann, Corinna, Shpacovitch, Victoria M., Seeliger, Stephan, Vergnolle, Nathalie, Vestweber, Dietmar, Luger, Thomas A., Schulze-Osthoff, Klaus, Steinhoff, Martin

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Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis von ENGELS, Ingo H, STEPCZYNSKA, Ania, GREGOR, Michael, SCHULZE-OSTHOFF, Klaus, WESSELBORG, Sebastian, STROH, Christopher, LAUBER, Kirsten, BERG, Christoph, SCHWENZER, Ralf, WAJANT, Harald, JÄNICKE, Reiner U, PORTER, Alan G, BELKA, Claus

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Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation von STEPCZYNSKA, Anna, LAUBER, Kirsten, ENGELS, Ingo H, JANSSEN, Ottmar, KABELITZ, Dieter, WESSELBORG, Sebastian, SCHULZE-OSTHOFF, Klaus

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Caspase-10 Sensitizes Breast Carcinoma Cells to TRAIL-Induced but Not Tumor Necrosis Factor-Induced Apoptosis in a Caspase- 3-Dependent Manner von Engels, Ingo H, Totzke, Gudrun, Fischer, Ute, Schulze-Osthoff, Klaus, Jänicke, Reiner U

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A biochemical screen for GroEL/GroES inhibitors von Johnson, Steven M., Sharif, Orzala, Mak, Puiying Annie, Wang, Hsiao-Ting, Engels, Ingo H., Brinker, Achim, Schultz, Peter G., Horwich, Arthur L., Chapman, Eli

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Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity von Barretina, Jordi, Caponigro, Giordano, Stransky, Nicolas, Venkatesan, Kavitha, Margolin, Adam A., Kim, Sungjoon, Wilson, Christopher J., Lehár, Joseph, Kryukov, Gregory V., Sonkin, Dmitriy, Reddy, Anupama, Liu, Manway, Murray, Lauren, Berger, Michael F., Monahan, John E., Morais, Paula, Meltzer, Jodi, Korejwa, Adam, Jané-Valbuena, Judit, Mapa, Felipa A., Thibault, Joseph, Bric-Furlong, Eva, Raman, Pichai, Shipway, Aaron, Engels, Ingo H., Cheng, Jill, Yu, Guoying K., Yu, Jianjun, Aspesi, Peter, de Silva, Melanie, Jagtap, Kalpana, Jones, Michael D., Wang, Li, Hatton, Charles, Palescandolo, Emanuele, Gupta, Supriya, Mahan, Scott, Sougnez, Carrie, Onofrio, Robert C., Liefeld, Ted, MacConaill, Laura, Winckler, Wendy, Reich, Michael, Li, Nanxin, Mesirov, Jill P., Gabriel, Stacey B., Getz, Gad, Ardlie, Kristin, Chan, Vivien, Myer, Vic E., Weber, Barbara L., Porter, Jeff, Warmuth, Markus, Finan, Peter, Harris, Jennifer L., Meyerson, Matthew, Golub, Todd R., Morrissey, Michael P., Sellers, William R., Schlegel, Robert, Garraway, Levi A.

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Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds von Crowther, Gregory J., Napuli, Alberto J., Gilligan, James H., Gagaring, Kerstin, Borboa, Rachel, Francek, Carolyn, Chen, Zhong, Dagostino, Eleanor F., Stockmyer, Justin B., Wang, Yu, Rodenbough, Philip P., Castaneda, Lisa J., Leibly, David J., Bhandari, Janhavi, Gelb, Michael H., Brinker, Achim, Engels, Ingo H., Taylor, Jennifer, Chatterjee, Arnab K., Fantauzzi, Pascal, Glynne, Richard J., Van Voorhis, Wesley C., Kuhen, Kelli L.

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Anticancer Drugs Induce Caspase-8/FLICE Activation and Apoptosis in the Absence of CD95 Receptor/Ligand Interaction von Wesselborg, Sebastian, Engels, Ingo H., Rossmann, Evi, Los, Marek, Schulze-Osthoff, Klaus

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Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis von BANTEL, H, ENGELS, I. H, VOELTER, W, SCHULZE-OSTHOFF, K, WESSELBORG, S

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Caspases: more than just killers? von Los, Marek, Stroh, Christopher, Jänicke, Reiner U, Engels, Ingo H, Schulze-Osthoff, Klaus

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A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity von Engels, Ingo H., Daguia, Catherine, Huynh, Truc, Urbina, Hugo, Buddenkotte, Jörg, Schumacher, Andrew, Caldwell, Jeremy S., Brinker, Achim

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Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells von JÄNICKE, Reiner U, ENGELS, Ingo H, DUNKERN, Torsten, KAINA, Bernd, SCHULZE-OSTHOFF, Klaus, PORTER, Alan G

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A Biochemical/Biophysical Assay Dyad for HTS-Compatible Triaging of Inhibitors of the HIV-1 Nef/Hck SH3 Interaction von Breuer, Sebastian, Espinola, Sheryll, Morelli, Xavier, Torbett, Bruce E, Arold, Stefan T, Engels, Ingo H

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