Sa2008 Efficacy and Safety of Linaclotide in Chronic Idiopathic Constipation Patients With Abdominal Bloating: Phase 3b Trial Results von Lacy, Brian E, Lembo, Anthony, Schey, Ron, Lavins, Bernard J, Eng, Paul F, Fox, Susan M, Jia, Xinwei D, Hao, Xinming, Currie, Mark G, Kurtz, Caroline B, Johnston, Jeffrey, Shiff, Steven J

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Management strategies for the treatment and prevention of postoperative/postdischarge nausea and vomiting: an updated review [version 1; peer review: awaiting peer review] von Elvir-Lazo, Ofelia Loani, White, Paul F, Yumul, Roya, Cruz Eng, Hillenn

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Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority t... von Lye, David C, Dr, Archuleta, Sophia, MD, Syed-Omar, Sharifah F, MMed, Low, Jenny G, MRCP, Oh, Helen M, FRCP, Wei, Yuan, MS, Fisher, Dale, Prof, Ponnampalavanar, Sasheela S L, MMed, Wijaya, Limin, MRCP, Lee, Linda K, MPH, Ooi, Eng-Eong, Prof, Kamarulzaman, Adeeba, Prof, Lum, Lucy C, Prof, Tambyah, Paul A, Prof, Leo, Yee-Sin, Prof

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Targeted methylation sequencing of plasma cell-free DNA for cancer detection and classification von Liu, L., Toung, J.M., Jassowicz, A.F., Vijayaraghavan, R., Kang, H., Zhang, R., Kruglyak, K.M., Huang, H.J., Hinoue, T., Shen, H., Salathia, N.S., Hong, D.S., Naing, A., Subbiah, V., Piha-Paul, S.A., Bibikova, M., Granger, G., Barnes, B., Shen, R., Gutekunst, K., Fu, S., Tsimberidou, A.M., Lu, C., Eng, C., Moulder, S.L., Kopetz, E.S., Amaria, R.N., Meric-Bernstam, F., Laird, P.W., Fan, J.-B., Janku, F.

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Structural basis for substrate selection by the SARS-CoV-2 replicase von Malone, Brandon F., Perry, Jason K., Olinares, Paul Dominic B., Lee, Hery W., Chen, James, Appleby, Todd C., Feng, Joy Y., Bilello, John P., Ng, Honkit, Sotiris, Johanna, Ebrahim, Mark, Chua, Eugene Y. D., Mendez, Joshua H., Eng, Ed T., Landick, Robert, Götte, Matthias, Chait, Brian T., Campbell, Elizabeth A., Darst, Seth A.

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Human TERT promoter mutations as a prognostic biomarker in glioma von Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.

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The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans von Izzi‐Engbeaya, Chioma, Comninos, Alexander N., Clarke, Sophie A., Jomard, Anne, Yang, Lisa, Jones, Sophie, Abbara, Ali, Narayanaswamy, Shakunthala, Eng, Pei Chia, Papadopoulou, Deborah, Prague, Julia K., Bech, Paul, Godsland, Ian F., Bassett, Paul, Sands, Caroline, Camuzeaux, Stephane, Gomez‐Romero, Maria, Pearce, Jake T. M., Lewis, Matthew R., Holmes, Elaine, Nicholson, Jeremy K., Tan, Tricia, Ratnasabapathy, Risheka, Hu, Ming, Carrat, Gaelle, Piemonti, Lorenzo, Bugliani, Marco, Marchetti, Piero, Johnson, Paul R., Hughes, Stephen J., James Shapiro, A. M., Rutter, Guy A., Dhillo, Waljit S.

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Use of herbal medication in the perioperative period: Potential adverse drug interactions von Elvir Lazo, Ofelia Loani, White, Paul F., Lee, Carol, Cruz Eng, Hillenn, Matin, Jenna M., Lin, Cory, Del Cid, Franklin, Yumul, Roya

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Rewriting yeast central carbon metabolism for industrial isoprenoid production von Meadows, Adam L., Hawkins, Kristy M., Tsegaye, Yoseph, Antipov, Eugene, Kim, Youngnyun, Raetz, Lauren, Dahl, Robert H., Tai, Anna, Mahatdejkul-Meadows, Tina, Xu, Lan, Zhao, Lishan, Dasika, Madhukar S., Murarka, Abhishek, Lenihan, Jacob, Eng, Diana, Leng, Joshua S., Liu, Chi-Li, Wenger, Jared W., Jiang, Hanxiao, Chao, Lily, Westfall, Patrick, Lai, Jefferson, Ganesan, Savita, Jackson, Peter, Mans, Robert, Platt, Darren, Reeves, Christopher D., Saija, Poonam R., Wichmann, Gale, Holmes, Victor F., Benjamin, Kirsten, Hill, Paul W., Gardner, Timothy S., Tsong, Annie E.

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Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials von Doebele, Robert C, Drilon, Alexander, Paz-Ares, Luis, Siena, Salvatore, Shaw, Alice T, Farago, Anna F, Blakely, Collin M, Seto, Takashi, Cho, Byung Chul, Tosi, Diego, Besse, Benjamin, Chawla, Sant P, Bazhenova, Lyudmila, Krauss, John C, Chae, Young Kwang, Barve, Minal, Garrido-Laguna, Ignacio, Liu, Stephen V, Conkling, Paul, John, Thomas, Fakih, Marwan, Sigal, Darren, Loong, Herbert H, Buchschacher, Gary L, Garrido, Pilar, Nieva, Jorge, Steuer, Conor, Overbeck, Tobias R, Bowles, Daniel W, Fox, Elizabeth, Riehl, Todd, Chow-Maneval, Edna, Simmons, Brian, Cui, Na, Johnson, Ann, Eng, Susan, Wilson, Timothy R, Demetri, George D

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Long-Term Results of the RAPCO Trials von Buxton, Brian F., Hayward, Philip A., Raman, Jai, Moten, Simon C., Rosalion, Alexander, Gordon, Ian, Seevanayagam, Siven, Matalanis, George, Benedetto, Umberto, Gaudino, Mario, Hare, David L.

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Coincidence study of core-ionized adamantane: site-sensitivity within a carbon cage? von Ganguly, Smita, Gisselbrecht, Mathieu, Eng-Johnsson, Per, Feifel, Raimund, Hervieux, Paul-Antoine, Alfaytarouni, Zeinab, Fink, Reinhold F, Díaz-Tendero, Sergio, Milosavljevi, Aleksandar R, Rousseau, Patrick, Maclot, Sylvain

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Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer von Singel, Kelly L., Grzankowski, Kassondra S., Khan, A. N. M. Nazmul H., Grimm, Melissa J., D’Auria, Anthony C., Morrell, Kayla, Eng, Kevin H., Hylander, Bonnie, Mayor, Paul C., Emmons, Tiffany R., Lénárt, Nikolett, Fekete, Rebeka, Környei, Zsuzsanna, Muthukrishnan, Uma, Gilthorpe, Jonathan D., Urban, Constantin F., Itagaki, Kiyoshi, Hauser, Carl J., Leifer, Cynthia, Moysich, Kirsten B., Odunsi, Kunle, Dénes, Ádám, Segal, Brahm H.

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Fully automated multi-grid cryoEM screening using Smart Leginon von Cheng, Anchi, Kim, Paul T, Kuang, Huihui, Mendez, Joshua H, Chua, Eugene Y D, Maruthi, Kashyap, Wei, Hui, Sawh, Anjelique, Aragon, Mahira F, Serbynovskyi, Viacheslav, Neselu, Kasahun, Eng, Edward T, Potter, Clinton S, Carragher, Bridget, Bepler, Tristan, Noble, Alex J

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Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease von Splinter, Kimberly, Adams, David R, Bacino, Carlos A, Bellen, Hugo J, Bernstein, Jonathan A, Cheatle-Jarvela, Alys M, Eng, Christine M, Esteves, Cecilia, Gahl, William A, Hamid, Rizwan, Jacob, Howard J, Kikani, Bijal, Koeller, David M, Kohane, Isaac S, Lee, Brendan H, Loscalzo, Joseph, Luo, Xi, McCray, Alexa T, Metz, Thomas O, Mulvihill, John J, Nelson, Stanley F, Palmer, Christina G.S, Phillips, John A, Pick, Leslie, Postlethwait, John H, Reuter, Chloe, Shashi, Vandana, Sweetser, David A, Tifft, Cynthia J, Walley, Nicole M, Wangler, Michael F, Westerfield, Monte, Wheeler, Matthew T, Wise, Anastasia L, Worthey, Elizabeth A, Yamamoto, Shinya, Ashley, Euan A

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Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 von Xu, Kai, Acharya, Priyamvada, Kong, Rui, Cheng, Cheng, Chuang, Gwo-Yu, Liu, Kevin, Louder, Mark K., O’Dell, Sijy, Rawi, Reda, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Asokan, Mangaiarkarasi, Bailer, Robert T., Chambers, Michael, Chen, Xuejun, Choi, Chang W., Dandey, Venkata P., Doria-Rose, Nicole A., Druz, Aliaksandr, Eng, Edward T., Farney, S. Katie, Foulds, Kathryn E., Geng, Hui, Georgiev, Ivelin S., Gorman, Jason, Hill, Kurt R., Jafari, Alexander J., Kwon, Young D., Lai, Yen-Ting, Lemmin, Thomas, McKee, Krisha, Ohr, Tiffany Y., Ou, Li, Peng, Dongjun, Rowshan, Ariana P., Sheng, Zizhang, Todd, John-Paul, Tsybovsky, Yaroslav, Viox, Elise G., Wang, Yiran, Wei, Hui, Yang, Yongping, Zhou, Amy F., Chen, Rui, Yang, Lu, Scorpio, Diana G., McDermott, Adrian B., Shapiro, Lawrence, Carragher, Bridget, Potter, Clinton S., Mascola, John R., Kwong, Peter D.

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Genomic basis for RNA alterations in cancer von Calabrese, Claudia, Davidson, Natalie R., Demircioğlu, Deniz, Fonseca, Nuno A., He, Yao, Kahles, André, Lehmann, Kjong-Van, Liu, Fenglin, Shiraishi, Yuichi, Soulette, Cameron M., Urban, Lara, Greger, Liliana, Li, Siliang, Liu, Dongbing, Perry, Marc D., Xiang, Qian, Zhang, Fan, Zhang, Junjun, Bailey, Peter, Erkek, Serap, Hoadley, Katherine A., Hou, Yong, Huska, Matthew R., Kilpinen, Helena, Korbel, Jan O., Marin, Maximillian G., Markowski, Julia, Nandi, Tannistha, Pan-Hammarström, Qiang, Pedamallu, Chandra Sekhar, Siebert, Reiner, Stark, Stefan G., Su, Hong, Tan, Patrick, Waszak, Sebastian M., Yung, Christina, Zhu, Shida, Awadalla, Philip, Creighton, Chad J., Meyerson, Matthew, Ouellette, B. F. Francis, Wu, Kui, Yang, Huanming, Brazma, Alvis, Brooks, Angela N., Göke, Jonathan, Rätsch, Gunnar, Schwarz, Roland F., Stegle, Oliver, Zhang, Zemin

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Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts von Frésard, Laure, Smail, Craig, Ferraro, Nicole M., Teran, Nicole A., Li, Xin, Smith, Kevin S., Bonner, Devon, Kernohan, Kristin D., Marwaha, Shruti, Zappala, Zachary, Balliu, Brunilda, Davis, Joe R., Liu, Boxiang, Prybol, Cameron J., Kohler, Jennefer N., Zastrow, Diane B., Reuter, Chloe M., Fisk, Dianna G., Grove, Megan E., Davidson, Jean M., Hartley, Taila, Joshi, Ruchi, Strober, Benjamin J., Utiramerur, Sowmithri, Lind, Lars, Ingelsson, Erik, Battle, Alexis, Bejerano, Gill, Bernstein, Jonathan A., Ashley, Euan A., Boycott, Kym M., Merker, Jason D., Wheeler, Matthew T., Montgomery, Stephen B.

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Personalized Antibodies for Gastroesophageal Adenocarcinoma (PANGEA): A Phase II Study Evaluating an Individualized Treatment Strategy for Metastatic Disease von Catenacci, Daniel V T, Moya, Stephanie, Lomnicki, Samantha, Chase, Leah M, Peterson, Bryan F, Reizine, Natalie, Alpert, Lindsay, Setia, Namrata, Xiao, Shu-Yuan, Hart, John, Siddiqui, Uzma D, Hogarth, D Kyle, Eng, Oliver S, Turaga, Kiran, Roggin, Kevin, Posner, Mitchell C, Chang, Paul, Narula, Sunil, Rampurwala, Murtuza, Ji, Yuan, Karrison, Theodore, Liao, Chih-Yi, Polite, Blase N, Kindler, Hedy L

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Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose von Renia, Laurent, Goh, Yun Shan, Rouers, Angeline, Le Bert, Nina, Chia, Wan Ni, Chavatte, Jean-Marc, Fong, Siew‐Wai, Chang, Zi Wei, Zhuo, Nicole Ziyi, Tay, Matthew Zirui, Chan, Yi-Hao, Tan, Chee Wah, Yeo, Nicholas Kim‐Wah, Amrun, Siti Naqiah, Huang, Yuling, Wong, Joel Xu En, Hor, Pei Xiang, Loh, Chiew Yee, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Carissimo, Guillaume, Dowla, Samanzer, Lim, Alicia Jieling, Zhang, Jinyan, Lim, Joey Ming Er, Wang, Cheng-I., Ding, Ying, Pada, Surinder, Sun, Louisa Jin, Somani, Jyoti, Lee, Eng Sing, Ong, Desmond Luan Seng, Leo, Yee‐Sin, MacAry, Paul A., Lin, Raymond Tzer Pin, Wang, Lin-Fa, Ren, Ee Chee, Lye, David C., Bertoletti, Antonio, Young, Barnaby Edward, Ng, Lisa F. P.

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