Population Pharmacokinetic Analysis of Tucatinib in Healthy Participants and Patients with Breast Cancer or Colorectal Cancer von Zhang, Daping, Taylor, Adekemi, Zhao, Jie Janet, Endres, Christopher J, Topletz-Erickson, Ariel

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Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy von Rubin, Leah H, Sacktor, Ned, Creighton, Jason, Du, Yong, Endres, Christopher J, Pomper, Martin G, Coughlin, Jennifer M

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The Pharmacokinetics and Safety of Tucatinib in Volunteers with Hepatic Impairment von Topletz-Erickson, Ariel R., Lee, Anthony J., Mayor, JoAl G., Sun, Hao, Abdulrasool, Layth I., Rustia, Evelyn L., Walker, Luke N., Endres, Christopher J.

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Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate... von Cho, Steve Y, Gage, Kenneth L, Mease, Ronnie C, Senthamizhchelvan, Srinivasan, Holt, Daniel P, Jeffrey-Kwanisai, Akimosa, Endres, Christopher J, Dannals, Robert F, Sgouros, George, Lodge, Martin, Eisenberger, Mario A, Rodriguez, Ronald, Carducci, Michael A, Rojas, Camilo, Slusher, Barbara S, Kozikowski, Alan P, Pomper, Martin G

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Tucatinib Inhibits Renal Transporters OCT2 and MATE Without Impacting Renal Function in Healthy Subjects von Topletz‐Erickson, Ariel R., Lee, Anthony J., Mayor, JoAl G., Rustia, Evelyn L., Abdulrasool, Layth I., Wise, Amanda L., Dailey, Ben, DeChenne, Sharon, Walker, Luke N., Alley, Stephen C., Endres, Christopher J.

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Population Pharmacokinetic Modeling and Exposure–Response Assessment for the Antibody‐Drug Conjugate Brentuximab Vedotin in Hodgkin's Lymphoma in the Phase III ECHELON‐1 Study... von Suri, Ajit, Mould, Diane R., Song, Gregory, Collins, Graham P., Endres, Christopher J., Gomez‐Navarro, Jesús, Venkatakrishnan, Karthik

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Neuroimaging of translocator protein in patients with systemic lupus erythematosus: a pilot study using [11C]DPA-713 positron emission tomography von Wang, Yuchuan, Coughlin, Jennifer M, Ma, Shuangchao, Endres, Christopher J, Kassiou, Michael, Sawa, Akira, Dannals, Robert F, Petri, Michelle, Pomper, Martin G

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The Iron Deficiency-Regulated Small Protein Effector FEP3/IRON MAN1 Modulates Interaction of BRUTUS-LIKE1 With bHLH Subgroup IVc and POPEYE Transcription Factors von Lichtblau, Daniela M., Schwarz, Birte, Baby, Dibin, Endres, Christopher, Sieberg, Christin, Bauer, Petra

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Risk‐Based Pharmacokinetic and Drug–Drug Interaction Characterization of Antibody–Drug Conjugates in Oncology Clinical Development: An International Consortium for Innovation and Q... von Li, Chunze, Menon, Rajeev, Walles, Markus, Singh, Renu, Upreti, Vijay V., Brackman, Deanna, Lee, Anthony J., Endres, Christopher J., Kumar, Seema, Zhang, Donglu, Barletta, Frank, Suri, Ajit, Hainzl, Dominik, Liao, Kai H., Lalovic, Bojan, Beaumont, Maribel, Zuo, Peiying, Mayer, Andrew P., Wei, Dong

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Creation of Novel Sensitive Probe Substrate and Moderate Inhibitor Models for a Comprehensive Prediction of CYP2C8 Interactions for Tucatinib von Templeton, Ian E., Rowland‐Yeo, Karen, Jones, Hannah M., Endres, Christopher J., Topletz‐Erickson, Ariel R., Sun, Hao, Lee, Anthony J.

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Evaluation of Safety and Clinically Relevant Drug–Drug Interactions with Tucatinib in Healthy Volunteers von Topletz-Erickson, Ariel, Lee, Anthony, Rustia, Evelyn L., Sun, Hao, Mayor, JoAl G., Abdulrasool, Layth I., Walker, Luke, Endres, Christopher J.

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Effect of Tucatinib on Cardiac Repolarization in Healthy Volunteers von Topletz-Erickson, Ariel R., Mayor, JoAl G., Liu, Hsu-Tai, Abdulrasool, Layth I., Endres, Christopher J.

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Initial Evaluation of 11C-DPA-713, a Novel TSPO PET Ligand, in Humans von Endres, Christopher J, Pomper, Martin G, James, Michelle, Uzuner, Ovsev, Hammoud, Dima A, Watkins, Crystal C, Reynolds, Aaron, Hilton, John, Dannals, Robert F, Kassiou, Michael

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The role of transporters in drug interactions von Endres, Christopher J., Hsiao, Peng, Chung, Francisco S., Unadkat, Jashvant D.

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Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl von Sun, Hao, Cardinal, Kristen A., Wienkers, Larry, Chin, Alice, Kumar, Vineet, Neace, Calvin, Henderson, Clark, Endres, Christopher J., Topletz-Erickson, Ariel, Regal, Kelly, Vo, Alex, Alley, Stephen C., Lee, Anthony J.

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Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies: Retrospective Analysis of Monkey as a Single Species for First-in-Human Prediction von Dong, Jennifer Q., Salinger, David H., Endres, Christopher J., Gibbs, John P., Hsu, Cheng-Pang, Stouch, Brian J., Hurh, Eunju, Gibbs, Megan

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Decreased microglial activation in MS patients treated with glatiramer acetate von Ratchford, John N., Endres, Christopher J., Hammoud, Dima A., Pomper, Martin G., Shiee, Navid, McGready, John, Pham, Dzung L., Calabresi, Peter A.

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Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV von Coughlin, Jennifer M., Wang, Yuchuan, Ma, Shuangchao, Yue, Chen, Kim, Pearl K., Adams, Ashley V., Roosa, Heidi V., Gage, Kenneth L., Stathis, Marigo, Rais, Rana, Rojas, Camilo, McGlothan, Jennifer L., Watkins, Crystal C., Sacktor, Ned, Guilarte, Tomas R., Zhou, Yun, Sawa, Akira, Slusher, Barbara S., Caffo, Brian, Kassiou, Michael, Endres, Christopher J., Pomper, Martin G.

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Brain Mu-Opioid Receptor Binding Predicts Treatment Outcome in Cocaine-Abusing Outpatients von Ghitza, Udi E, Preston, Kenzie L, Epstein, David H, Kuwabara, Hiroto, Endres, Christopher J, Bencherif, Badreddine, Boyd, Susan J, Copersino, Marc L, Frost, J. James, Gorelick, David A

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Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2) von Horti, Andrew G., Gao, Yongjun, Ravert, Hayden T., Finley, Paige, Valentine, Heather, Wong, Dean F., Endres, Christopher J., Savonenko, Alena V., Dannals, Robert F.

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