IL-2 based cancer immunotherapies: an evolving paradigm von Rokade, Sushama, Damani, Anita Mehta, Oft, Martin, Emmerich, Jan

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1053 Preclinical pharmacodynamic characterization of STK-026: a novel IL-12 partial agonist for cancer with maintained CD8 T cell activity, reduced NK-mediated toxicity and an impr... von Koliesnik, Zhenya, Totagrande, Michael, Burgess, Ryan, Tran, Kim Q, Bauer, Michele, Jayaraman, Bharghavi, Buffone, Cindy, Balasubrahmanyam, Priyanka, Emmerich, Jan, Chaturvedi, Deepti, Rokkam, Deepti, Malefyt, Rene De Waal, Greb, Heiko, Ratti, Navneet, Vivona, Sandro, Kastelein, Robert, Lupardus, Patrick, Zuniga, Luis, Rosen, David B, Oft, Martin

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Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance von Klein, Ludger, Nedjic, Jelena, Aichinger, Martin, Emmerich, Jan, Mizushima, Noboru

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Autochthonous T cells to the rescue: IL-10 directly activates tumor-resident CD8+ T cells von Emmerich, Jan, Mumm, John B., Oft, Martin

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IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without De Novo Infiltration from Secondary Lymphoid Organs von EMMERICH, Jan, MUMM, John B, CHAN, Ivan H, LAFACE, Drake, TRUONG, Hoa, MCCLANAHAN, Terrill, GORMAN, Daniel M, OFT, Martin

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Killing from within von Mumm, John B., Emmerich, Jan, Oft, Martin

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Das lumbale Facettensyndrom als Prototyp einer Funktionskrankheit des Bewegungssystems von Emmerich, Jan

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Das lumbale Facettensyndrom als Prototyp einer Funktionskrankheit des Bewegungssystems: Leitliniengerechte Diagnostik und Behandlung von Emmerich, Jan

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Multimodale Komplexbehandlung des Bewegungssystems – Hintergründe, Entwicklung medizinischer Strukturen und Durchführung von Emmerich, Jan

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Selection of Foxp3 + regulatory T cells specific for self antigen expressed and presented by Aire + medullary thymic epithelial cells von Klein, Ludger, Aschenbrenner, Katharina, D'Cruz, Louise M, Vollmann, Elisabeth H, Hinterberger, Maria, Emmerich, Jan, Swee, Lee Kim, Rolink, Antonius

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IL-10 Elicits IFNγ-Dependent Tumor Immune Surveillance von Mumm, John B., Emmerich, Jan, Zhang, Xueqing, Chan, Ivan, Wu, Lingling, Mauze, Smita, Blaisdell, Steven, Basham, Beth, Dai, Jie, Grein, Jeff, Sheppard, Catherine, Hong, Kyu, Cutler, Collette, Turner, Scott, LaFace, Drake, Kleinschek, Melanie, Judo, Michael, Ayanoglu, Gulesi, Langowski, John, Gu, Danling, Paporello, Brittany, Murphy, Erin, Sriram, Venkataraman, Naravula, Saraswathi, Desai, Bela, Medicherla, Satya, Seghezzi, Wolfgang, McClanahan, Terrill, Cannon-Carlson, Susan, Beebe, Amy M., Oft, Martin

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THE SIGNIFICANCE OF THE CRIMEAN BRIDGE FOR RUSSIA: A POWER TOOL WITH STRATEGIC, LEGAL, AND SYMBOLIC VALUE von Emmerich, Jan

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Abstract 1744: STK-012, an alpha/beta selective IL-2 mutein for the activation of the antigen-activated T cells in solid tumor von Emmerich, Jan, Bauer, Michele, Semana, Marie, Jayaraman, Bhargavi, Vivona, Sandro, McCauley, Scott, Riener, Romina, Malefyt, Rene De Waal, Aspuria, Paul-Joseph, Rokkam, Deepti, Lupardus, Patrick, Kastelein, Rob, Oft, Martin

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Abstract 1512: OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumor efficacy by driving T cell expansion and fitness von Aspuria, Paul-Joseph P., Vivona, Sandro, Bauer, Michele, Semana, Marie, Ratti, Navneet, McCauley, Scott, Riener, Romina, Malefyt, Rene de Waal, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin

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OrthoCARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell antitumorefficacy von Aspuria, Paul-Joseph, Bauer, Michael A, vivona, Sandro, de Waal Malefyt, Rene, Kastelein, Rob, Oft, Martin, Emmerich, Jan, Rokkam, Deepti, Kauder, Steven E, McCauley, Scott, Riener, Romina, Verma, Rakesh

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Abstract 3252: Ortho CARs: Engineered human IL-2/IL-2Rb orthogonal pairs selectively enhance CAR T cell anti-tumor efficacy and durability of response von Aspuria, Paul-Joseph, Bauer, Michele, Vivona, Sandro, Kauder, Steven E., McCauley, Scott, Riener, Romina, Malefyte, Rene De Waal, Ratti, Navneet, Rokkam, Deepti, Emmerich, Jan, Lupardus, Patrick J., Kastelein, Rob A., Oft, Martin

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Drosophila p27Dacapo expression during embryogenesis is controlled by a complex regulatory region independent of cell cycle progression von Meyer, Claas A, Kramer, Ina, Dittrich, Rainer, Marzodko, Sandra, Emmerich, Jan, Lehner, Christian F

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Abstract 586: Orthogonal IL-2/IL-2RB signaling in adoptively transferred T cells controls tumor growth without the need for lymphodepletion in a B16 tumor model von Kochel, Christina, Sun, Meng, Ratti, Navneet, Vivona, Sandro, Ramadass, Mahalaksmi, Semana, Marie, Bauer, Michele, Ali, Mohammed, Emmerich, Jan, Kastelein, Rob, Lupardus, Patrick J., Aspuria, Paul-Joseph, Oft, Martin

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A measurement platform for photovoltaic performance analysis in environments with ultra-low energy harvesting potential von Masoudinejad, Mojtaba, Emmerich, Jan, Kossmann, Dominik, Riesner, Andreas, Roidl, Moritz, ten Hompel, Michael

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Abstract 1833: Novel IL-12 Partial Agonist For Cancer Immunotherapy Avoids NK-cell Mediated Toxicity von Koliesnik, Ievgen, Emmerich, Jan, Tran, Kim Q., Bauer, Michele, Totagrande, Michael, Jayaraman, Bhargavi, Buffone, Cindy, Balasubrahmanyam, Priyanka, Rokkam, Deepti, Malefyt, Rene de Waal, Zuniga, Luis, Greb, Heiko, Ratti, Navneet, Vivona, Sandro, Oft, Martin, Lupardus, Patrick J., Kastelein, Robert A.

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