BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program von Ren, Decheng, Tu, Ho-Chou, Kim, Hyungjin, Wang, Gary X, Bean, Gregory R, Takeuchi, Osamu, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D, Cheng, Emily H.-Y

Volltext

BAX activation is initiated at a novel interaction site von Tjandra, Nico, Walensky, Loren D, Gavathiotis, Evripidis, Suzuki, Motoshi, Davis, Marguerite L, Pitter, Kenneth, Bird, Gregory H, Katz, Samuel G, Tu, Ho-Chou, Kim, Hyungjin, Cheng, Emily H.-Y

Volltext

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis von Kim, Hyungjin, Tu, Ho-Chou, Ren, Decheng, Takeuchi, Osamu, Jeffers, John R., Zambetti, Gerard P., Hsieh, James J.-D., Cheng, Emily H.-Y.

Volltext

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies von Cheng, Emily H.-Y, Kim, Hyungjin, Rafiuddin-Shah, Mubina, Tu, Ho-Chou, Jeffers, John R, Zambetti, Gerard P, Hsieh, James J.-D

Volltext

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death von Wei, Michael C., Zong, Wei-Xing, Emily H. -Y. Cheng, Lindsten, Tullia, Panoutsakopoulou, Vily, Ross, Andrea J., Roth, Kevin A., MacGregor, Grant R., Thompson, Craig B., Korsmeyer, Stanley J.

Volltext

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis von Emily H. -Y. Cheng, Sheiko, Tatiana V., Fisher, Jill K., Craigen, William J., Korsmeyer, Stanley J.

Volltext

Asparagine Plays a Critical Role in Regulating Cellular Adaptation to Glutamine Depletion von Zhang, Ji, Fan, Jing, Venneti, Sriram, Cross, Justin R., Takagi, Toshimitsu, Bhinder, Bhavneet, Djaballah, Hakim, Kanai, Masayuki, Cheng, Emily H., Judkins, Alexander R., Pawel, Bruce, Baggs, Julie, Cherry, Sara, Rabinowitz, Joshua D., Thompson, Craig B.

Volltext

Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint von Hsieh, James J.-D, Liu, Han, Takeda, Shugaku, Kumar, Rakesh, Westergard, Todd D, Brown, Eric J, Pandita, Tej K, Cheng, Emily H.-Y

Volltext

Chromosome 3p Loss-Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma von Hsieh, James J, Le, Valerie H, Oyama, Toshinao, Ricketts, Christopher J, Ho, Thai Huu, Cheng, Emily H

Volltext

An Integrated Metabolic Atlas of Clear Cell Renal Cell Carcinoma von Hakimi, A. Ari, Reznik, Ed, Lee, Chung-Han, Creighton, Chad J., Brannon, A. Rose, Luna, Augustin, Aksoy, B. Arman, Liu, Eric Minwei, Shen, Ronglai, Lee, William, Chen, Yang, Stirdivant, Steve M., Russo, Paul, Chen, Ying-Bei, Tickoo, Satish K., Reuter, Victor E., Cheng, Emily H., Sander, Chris, Hsieh, James J.

Volltext

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures von Şenbabaoğlu, Yasin, Gejman, Ron S, Winer, Andrew G, Liu, Ming, Van Allen, Eliezer M, de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J, Khalil, Danny N, Kaffenberger, Samuel D, Chen, Yingbei, Danilova, Ludmila, Voss, Martin H, Coleman, Jonathan A, Russo, Paul, Reuter, Victor E, Chan, Timothy A, Cheng, Emily H, Scheinberg, David A, Li, Ming O, Choueiri, Toni K, Hsieh, James J, Sander, Chris, Hakimi, A Ari

Volltext

Facial Nerve Paralysis and COVID‐19: A Systematic Review von Namavarian, Amirpouyan, Eid, Anas, Ziai, Hedyeh, Cheng, Emily YiQin, Enepekides, Danny

Volltext

Genomic classifications of renal cell carcinoma: a critical step towards the future application of personalized kidney cancer care with pan‐omics precision von Hsieh, James J, Le, Valerie, Cao, Dengfeng, Cheng, Emily H, Creighton, Chad J

Volltext

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy von Chen, Yun, Lewis, William, Diwan, Abhinav, Cheng, Emily H.-Y., Matkovich, Scot J., Dorn, Gerald W., Olson, Eric N.

Volltext

Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosis von Gitego, Nadege, Agianian, Bogos, Mak, Oi Wei, Kumar MV, Vasantha, Cheng, Emily H., Gavathiotis, Evripidis

Volltext

An interconnected hierarchical model of cell death regulation by the BCL-2 family von Chen, Hui-Chen, Kanai, Masayuki, Inoue-Yamauchi, Akane, Tu, Ho-Chou, Huang, Yafen, Ren, Decheng, Kim, Hyungjin, Takeda, Shugaku, Reyna, Denis E., Chan, Po M., Ganesan, Yogesh Tengarai, Liao, Chung-Ping, Gavathiotis, Evripidis, Hsieh, James J., Cheng, Emily H.

Volltext

PUMA and BIM are required for oncogene inactivation-induced apoptosis von Bean, Gregory R, Ganesan, Yogesh Tengarai, Dong, Yiyu, Takeda, Shugaku, Liu, Han, Chan, Po M, Huang, Yafen, Chodosh, Lewis A, Zambetti, Gerard P, Hsieh, James J-D, Cheng, Emily H-Y

Volltext

An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway von Garner, Thomas P., Reyna, Denis E., Priyadarshi, Amit, Chen, Hui-Chen, Li, Sheng, Wu, Yang, Ganesan, Yogesh Tengarai, Malashkevich, Vladimir N., Cheng, Emily H., Gavathiotis, Evripidis

Volltext

Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy von Inoue-Yamauchi, Akane, Jeng, Paul S., Kim, Kwanghee, Chen, Hui-Chen, Han, Song, Ganesan, Yogesh Tengarai, Ishizawa, Kota, Jebiwott, Sylvia, Dong, Yiyu, Pietanza, Maria C., Hellmann, Matthew D., Kris, Mark G., Hsieh, James J., Cheng, Emily H.

Volltext

The VDAC2-BAK axis regulates peroxisomal membrane permeability von Hosoi, Ken-Ichiro, Miyata, Non, Mukai, Satoru, Furuki, Satomi, Okumoto, Kanji, Cheng, Emily H, Fujiki, Yukio

Volltext