AZD3293 A novel BACE1 inhibitor: safety, tolerability, and effects on plasma and CSF Aβ peptides following single- and multiple-dose administration von Alexander, Robert, Budd, S, Russell, M, Kugler, A, Cebers, G, Ye, N, Olsson, T, Burdette, D, Maltby, J, Paraskos, J, Elsby, K, Han, D, Goldwater, R, Ereshefsky, L

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B31 INFLAMMATION AND COPD: Azd7624, An Inhaled P38 Inhibitor For COPD, Suppresses Lipopolysaccharide-Induced Airway Inflammation von Fageras, M, Taib, Z, Cunoosamy, D, Elsby, K, Jansson, P, Patel, N

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Understanding the Critical Disposition Pathways of Statins to Assess Drug-Drug Interaction Risk During Drug Development: It's Not Just About OATP1B1 von Elsby, R, Hilgendorf, C, Fenner, K

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver von Chu, X, Korzekwa, K, Elsby, R, Fenner, K, Galetin, A, Lai, Y, Matsson, P, Moss, A, Nagar, S, Rosania, G R, Bai, J P F, Polli, J W, Sugiyama, Y, Brouwer, K L R

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Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold... von Elsby, Robert, Martin, Paul, Surry, Dominic, Sharma, Pradeep, Fenner, Katherine

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Iron-SNS and -CNS Complexes: Selective Caryl–S Bond Cleavage and Amine-Borane Dehydrogenation Catalysis von Elsby, Matthew R, Ghostine, Karine, Das, Uttam K, Gabidullin, Bulat M, Baker, R. Tom

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Rosuvastatin pharmacokinetics and pharmacogenetics in Caucasian and Asian subjects residing in the United States von Birmingham, Bruce K., Bujac, Sarah R., Elsby, Robert, Azumaya, Connie T., Zalikowski, Julie, Chen, Yusong, Kim, Kenneth, Ambrose, Helen J.

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Impact of ABCG2 and SLCO1B1 polymorphisms on pharmacokinetics of rosuvastatin, atorvastatin and simvastatin acid in Caucasian and Asian subjects: a class effect? von Birmingham, Bruce K., Bujac, Sarah R., Elsby, Robert, Azumaya, Connie T., Wei, Cheryl, Chen, Yusong, Mosqueda-Garcia, Rogelio, Ambrose, Helen J.

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Iron-SNS and -CNS Complexes: Selective C aryl –S Bond Cleavage and Amine-Borane Dehydrogenation Catalysis von Elsby, Matthew R., Ghostine, Karine, Das, Uttam K., Gabidullin, Bulat M., Baker, R. Tom

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Increased Constitutive c-Jun N-terminal Kinase Signaling in Mice Lacking Glutathione S-Transferase Pi von Elsby, Robert, Kitteringham, Neil R, Goldring, Christopher E, Lovatt, Cerys A, Chamberlain, Mark, Henderson, Colin J, Wolf, C Roland, Park, B Kevin

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Activation of hepatic Nrf2 in vivo by acetaminophen in CD‐1 mice von Goldring, Christopher E. P., Kitteringham, Neil R., Elsby, Robert, Randle, Laura E., Clement, Yuri N., Williams, Dominic P., McMahon, Michael, Hayes, John D., Itoh, Ken, Yamamoto, Masayuki, Park, B. Kevin

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A novel association between residual renal function and left ventricular hypertrophy in peritoneal dialysis patients von Wang, Angela Yee-Moon, Wang, Mei, Woo, Jean, Law, Man-Ching, Chow, Kai-Ming, Li, Philip Kam-Tao, Lui, Siu-Fai, Sanderson, John Elsby

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Cetacean Strandings in the US Pacific Northwest 2000–2019 Reveal Potential Linkages to Oceanographic Variability von Warlick, Amanda J., Huggins, Jessica L., Lambourn, Dyanna M., Duffield, Deborah A., D’Alessandro, Dalin N., Rice, James M., Calambokidis, John, Hanson, M. Bradley, Gaydos, Joseph K., Jeffries, Steven J., Olson, Jennifer K., Scordino, Jonathan J., Akmajian, Adrianne M., Klope, Matthew, Berta, Susan, Dubpernell, Sandy, Carlson, Betsy, Riemer, Susan, Hodder, Jan, Souze, Victoria, Elsby, Alysha, King, Cathy, Wilkinson, Kristin, Boothe, Tiffany, Norman, Stephanie A.

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Relative and absolute quantitative expression profiling of cytochromes P450 using isotope-coded affinity tags von Jenkins, Rosalind E., Kitteringham, Neil R., Hunter, Christie L., Webb, Sally, Hunt, Tony J., Elsby, Robert, Watson, Rod B., Williams, Dominic, Penningtonand, Stephen R., Park, B. Kevin

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FRET evidence for a conformational change in TFIIB upon TBP‐DNA binding von Zheng, Le, Hoeflich, Klaus P., Elsby, Laura M., Ghosh, Mahua, Roberts, Stefan G. E., Ikura, Mitsuhiko

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver : Transporters in Drug Development and Clinical Pharmacology von CHU, X, KORZEKWA, K, BAI, Jpf, POLLI, J. W, SUGIYAMA, Y, BROUWER, Klr, ELSBY, R, FENNER, K, GALETIN, A, LAI, Y, MATSSON, P, MOSS, A, NAGAR, S, ROSANIA, G. R

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Probing Zn2+-binding effects on the zinc-ribbon domain of human general transcription factor TFIIB von Ghosh, Mahua, Elsby, Laura M, Mal, Tapas K, Gooding, Jane M, Roberts, Stefan G E, Ikura, Mitsuhiko

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Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor von Elsby, Robert, Ashby, John, Sumpter, John P, Brooks, A.Nigel, Pennie, William D, Maggs, James L, Lefevre, Paul A, Odum, Jenny, Beresford, Nicola, Paton, David, Park, B.Kevin

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Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver von Kitteringham, Neil R., Powell, Helen, Jenkins, Rosalind E., Hamlett, Jane, Lovatt, Cerys, Elsby, Robert, Henderson, Colin J., Wolf, C. Roland, Pennington, Stephen R., Park, B. Kevin

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Magnetic resonance angiography of coronary arteries with a 3-dimensional magnetization-prepared true fast imaging with steady-state precession sequence compared with conventional c... von So, Nina Man-ching, Lam, Wynnie Wai-man, Li, Debiao, Chan, Anna Kin-Yin, Sanderson, John Elsby, Metreweli, Constantine

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