Design, synthesis and in silico studies of new quinazolinone derivatives as antitumor PARP-1 inhibitors von Ramadan, Sayed K, Elrazaz, Eman Z, Abouzid, Khaled A M, El-Naggar, Abeer M

Volltext

FLT3-PROTACs for combating AML resistance: Analytical overview on chimeric agents developed, challenges, and future perspectives von Hesham, Heba M., Dokla, Eman M.E., Elrazaz, Eman Z., Lasheen, Deena S., Abou El Ella, Dalal A.

Volltext

Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies von Eldeeb, Assem H., Abo-Ashour, Mahmoud F., Angeli, Andrea, Bonardi, Alessandro, Lasheen, Deena S., Elrazaz, Eman Z., Nocentini, Alessio, Gratteri, Paola, Abdel-Aziz, Hatem A., Supuran, Claudiu T.

Volltext

Discovery of pyrano[2,3-]pyrimidine-2,4-dione derivatives as novel PARP-1 inhibitors: design, synthesis and antitumor activity von Abd El-sattar, Nour E. A, Badawy, Eman H. K, Elrazaz, Eman Z, Ismail, Nasser S. M

Volltext

Novel sulfonamide-indolinone hybrids targeting mitochondrial respiration of breast cancer cells von Helmy, Sama W.A., Abdel-Aziz, Amal Kamal, Dokla, Eman M.E., Ahmed, Tarek E., Hatem, Yasmin, Abdel Rahman, Engy A., Sharaky, Marwa, Shahin, Mai I., Elrazaz, Eman Z., Serya, Rabah A.T., Henary, Maged, Ali, Sameh S., Abou El Ella, Dalal A.

Volltext

Discovery of potent thieno[2,3-d]pyrimidine VEGFR-2 inhibitors: Design, synthesis and enzyme inhibitory evaluation supported by molecular dynamics simulations von Elrazaz, Eman Z., Serya, Rabah A.T., Ismail, Nasser S.M., Albohy, Amgad, Abou El Ella, Dalal A., Abouzid, Khaled A.M.

Volltext

Novel quinazolinone Derivatives: Design, synthesis and in vivo evaluation as potential agents targeting Alzheimer disease von Moftah, Hadeer K., Mousa, Mai H.A., Elrazaz, Eman Z., Kamel, Ahmed S., Lasheen, Deena S., Georgey, Hanan H.

Volltext

Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitors von Hadi, Soha R. Abd El, Lasheen, Deena S., Soliman, Dalia H., Elrazaz, Eman Z., Abouzid, Khaled A.M.

Volltext

Fragment merging approach for design, synthesis, and biological assessment of urea/acetyl hydrazide clubbed thienopyrimidine derivatives as GSK-3β inhibitors von Saleh, Joseph S., Abd El Hadi, Soha R., Ibrahim, Hany S., Elrazaz, Eman Z., Abouzid, Khaled A. M.

Volltext

Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo[1,5-a]pyrimidines as novel larotrectinib analogs von Attia, Mohamed H., Elrazaz, Eman Z., El-Emam, Soad Z., Taher, Azza T., Abdel-Aziz, Hatem A., Abouzid, Khaled A.M.

Volltext

Synthesis of some tropane-based compounds targeting colon cancer von Samir, Nermin, George, Riham F, Elrazaz, Eman Z, Ayoub, Iriny M, Shalaby, ElSayed M, Plaisier, Jasper R, Demitri, Nicola, Wink, Michael

Volltext

Synthesis and antimicrobial evaluation of new halogenated 1,3-Thiazolidin-4-ones von Hammad, Shaymaa G., El-Gazzar, Marwa G., Abutaleb, Nader S., Li, Daoyi, Ramming, Isabell, Shekhar, Aditya, Abdel-Halim, Mohammad, Elrazaz, Eman Z., Seleem, Mohamed N., Bilitewski, Ursula, Abouzid, Khaled A.M., El-Hossary, Ebaa M.

Volltext

Facile one-pot synthesis of thiazol-2(3H)-imine derivatives from α-active methylene ketones von El-Sawah, Dalia, Loksha, Yasser, Elrazaz, Eman, Abboud, Khalil, Webster, Bradley, Abouzid, Khaled

Volltext

Green synthesis and 3D pharmacophore study of pyrimidine and glucoside derivatives with in vitro potential anticancer and antioxidant activities von Salem, Mounir A., Behalo, Mohamed S., Elrazaz, Eman

Volltext

Synthesis and QSAR Study of Some Novel Heterocyclic Derivatives as In Vitro Cytotoxic Agents von Rizk, Sameh A., Abdelwahab, Salwa S., Elrazaz, Eman

Volltext

Fragment merging approach for design, synthesis, and biological assessment of urea/acetyl hydrazide clubbed thienopyrimidine derivatives as GSK-3[beta] inhibitors von Saleh, Joseph S, Abd El Hadi, Soha R, Ibrahim, Hany S, Elrazaz, Eman Z, Abouzid, Khaled A. M

Volltext

Design, synthesis and studies of new quinazolinone derivatives as antitumor PARP-1 inhibitors von Ramadan, Sayed K, Elrazaz, Eman Z, Abouzid, Khaled A. M, El-Naggar, Abeer M

Volltext