The Staurosporine-Like Compound L-753,000 (NB-506) Potentiates the Neurotrophic Effects of Neurotrophin-3 by Acting Selectively at the TrkA Receptor von Pollack, S, Young, L, Bilsland, J, Wilkie, N, Ellis, S, Hefti, F, Broughton, H, Harper, S

Volltext

Intra- or Intercomplex Binding to the γ-Secretase Enzyme: A MODEL TO DIFFERENTIATE INHIBITOR CLASSES von Clarke, Earl E, Churcher, Ian, Ellis, Semantha, Wrigley, Jonathan D.J, Lewis, Huw D, Harrison, Timothy, Shearman, Mark S, Beher, Dirk

Volltext

Functional Overexpression of γ-Secretase Reveals Protease-independent Trafficking Functions and a Critical Role of Lipids for Protease Activity von Wrigley, Jonathan D.J., Schurov, Irina, Nunn, Emma J., Martin, Agnes C.L., Clarke, Earl E., Ellis, Semantha, Bonnert, Timothy P., Shearman, Mark S., Beher, Dirk

Volltext

Intra- or Intercomplex Binding to the γ-Secretase Enzyme von Clarke, Earl E., Churcher, Ian, Ellis, Semantha, Wrigley, Jonathan D.J., Lewis, Huw D., Harrison, Timothy, Shearman, Mark S., Beher, Dirk

Volltext

Intra- or Intercomplex Binding to the γ-Secretase Enzyme von Earl E. Clarke, Ian Churcher, Semantha Ellis, Jonathan D. J. Wrigley, Huw D. Lewis, Timothy Harrison, Mark S. Shearman, Dirk Beher

Volltext

Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors von Fricker, Michael, LoGrasso, Philip, Ellis, Semantha, Wilkie, Neil, Hunt, Peter, Pollack, Scott J.

Volltext

S2-03-02: Mechanistic differences in targeting γ-secretase with inhibitors von Beher, Dirk, Clarke, Earl E., Wrigley, Jonathan D.J., Churcher, Ian, Ellis, Semantha, Lewis, Huw D., Harrison, Timothy, Shearman, Mark S.

Volltext