Sub-region-Specific Optic Nerve Head Glial Activation in Glaucoma von Oikawa, Kazuya, Ver Hoeve, James N., Teixeira, Leandro B. C., Snyder, Kevin C., Kiland, Julie A., Ellinwood, N. Matthew, McLellan, Gillian J.

Volltext

An exonic insertion in the NAGLU gene causing Mucopolysaccharidosis IIIB in Schipperke dogs von Raj, Karthik, Ellinwood, N. Matthew, Giger, Urs

Volltext

Derivation of adult canine intestinal organoids for translational research in gastroenterology von Chandra, Lawrance, Borcherding, Dana C, Kingsbury, Dawn, Atherly, Todd, Ambrosini, Yoko M, Bourgois-Mochel, Agnes, Yuan, Wang, Kimber, Michael, Qi, Yijun, Wang, Qun, Wannemuehler, Michael, Ellinwood, N Matthew, Snella, Elizabeth, Martin, Martin, Skala, Melissa, Meyerholz, David, Estes, Mary, Fernandez-Zapico, Martin E, Jergens, Albert E, Mochel, Jonathan P, Allenspach, Karin

Volltext

Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions von Egeland, Martin T., Tarczyluk-Wells, Marta M., Asmar, Melissa M., Adintori, Evan G., Lawrence, Roger, Snella, Elizabeth M., Jens, Jackie K., Crawford, Brett E., Wait, Jill C. M., McCullagh, Emma, Pinkstaff, Jason, Cooper, Jonathan D., Ellinwood, N. Matthew

Volltext

Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor von Brim, B.L., Haskell, R., Awedikian, R., Ellinwood, N.M., Jin, L., Kumar, A., Foster, T.C., Magnusson, K.R.

Volltext

Community consensus for Heparan sulfate as a biomarker to support accelerated approval in Neuronopathic Mucopolysaccharidoses von Muenzer, Joseph, Ho, Carole, Lau, Heather, Dant, Mark, Fuller, Maria, Boulos, Nidal, Dickson, Patricia, Ellinwood, N. Matthew, Jones, Simon A., Zanelli, Eric, O'Neill, Cara

Volltext

A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus) von Kuehn, Markus H, Lipsett, Koren A, Menotti-Raymond, Marilyn, Whitmore, S Scott, Scheetz, Todd E, David, Victor A, O'Brien, Stephen J, Zhao, Zhongyuan, Jens, Jackie K, Snella, Elizabeth M, Ellinwood, N Matthew, McLellan, Gillian J

Volltext

Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I von Khalid, Omar, Vera, Moin U, Gordts, Philip L, Ellinwood, N Matthew, Schwartz, Philip H, Dickson, Patricia I, Esko, Jeffrey D, Wang, Raymond Y

Volltext

Clinical and pathological characterization of ophthalmic disease in a canine model of mucopolysaccharidosis type I von Nenninger, Ariel, Ben‐Shlomo, Gil, Allbaugh, Rachel, Valentine, Bethann, Snella, Elizabeth, Jens, Jackie, Ellinwood, N. Matthew, Smith, Jodi

Volltext

Differential Transcriptomic Profiles Following Stimulation with Lipopolysaccharide in Intestinal Organoids from Dogs with Inflammatory Bowel Disease and Intestinal Mast Cell Tumor von Sahoo, Dipak Kumar, Borcherding, Dana C, Chandra, Lawrance, Jergens, Albert E, Atherly, Todd, Bourgois-Mochel, Agnes, Ellinwood, N Matthew, Snella, Elizabeth, Severin, Andrew J, Martin, Martin, Allenspach, Karin, Mochel, Jonathan P

Volltext

Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues von Müller, Brigitte, Ellinwood, N M, Lorenz, Birgit, Stieger, Knut

Volltext

The post-natal development of intraocular pressure in normal domestic cats (Felis catus) and in feline congenital glaucoma von Adelman, Sara, Shinsako, Daniel, Kiland, Julie A., Yaccarino, Vincent, Ellinwood, N. Matthew, Ben-Shlomo, Gil, McLellan, Gillian J.

Volltext

Temporospatial Development of Neuropathologic Findings in a Canine Model of Mucopolysaccharidosis IIIB von Harm, Tyler A., Hostetter, Shannon J., Nenninger, Ariel S., Valentine, Bethann N., Ellinwood, N. Matthew, Smith, Jodi D.

Volltext

Prolonged Expression of Secreted Enzymes in Dogs After Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease von Aronovich, Elena L, Hyland, Kendra A, Hall, Bryan C, Bell, Jason B, Olson, Erik R, Rusten, Myra Urness, Hunter, David W, Ellinwood, N Matthew, McIvor, R Scott, Hackett, Perry B

Volltext

Not All SCID Pigs Are Created Equally: Two Independent Mutations in the Artemis Gene Cause SCID in Pigs von Waide, Emily H, Dekkers, Jack C M, Ross, Jason W, Rowland, Raymond R R, Wyatt, Carol R, Ewen, Catherine L, Evans, Alyssa B, Thekkoot, Dinesh M, Boddicker, Nicholas J, Serão, Nick V L, Ellinwood, N Matthew, Tuggle, Christopher K

Volltext

Issues of COVID-19-related distance learning for children with neuronopathic mucopolysaccharidoses von Eisengart, Julie B., Esler, Amy N., Ellinwood, N. Mathew, Hudock, Rebekah L., King, Kelly E., Klein, Terri L., Lee, Chimei, Morton, Jonathan, Stephens, Kim, Ziegler, Richard, O'Neill, Cara

Volltext

Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB von Ellinwood, N. Matthew, Valentine, Bethann N., Hess, Andrew S., Jens, Jackie K., Snella, Elizabeth M., Jamil, Maryam, Hostetter, Shannon J., Jeffery, Nicholas D., Smith, Jodi D., Millman, Suzanne T., Parsons, Rebecca L., Butt, Mark T., Chandra, Sundeep, Egeland, Martin T., Assis, Ana B., Nelvagal, Hemanth R., Cooper, Jonathan D., Nestrasil, Igor, Mueller, Bryon A., Labounek, Rene, Paulson, Amy, Prill, Heather, Liu, Xiao Ying, Zhou, Huiyu, Lawrence, Roger, Crawford, Brett E., Grover, Anita, Cherala, Ganesh, Melton, Andrew C., Cherukuri, Anu, Vuillemenot, Brian R., Wait, Jill C.M., O’Neill, Charles A., Pinkstaff, Jason, Kovalchin, Joseph, Zanelli, Eric, McCullagh, Emma

Volltext

Timing is everything: Clinical courses of Hunter syndrome associated with age at initiation of therapy in a sibling pair von Grant, Nathan, Sohn, Young Bae, Ellinwood, N. Matthew, Okenfuss, Ericka, Mendelsohn, Bryce A., Lynch, Leslie E., Braunlin, Elizabeth A., Harmatz, Paul R., Eisengart, Julie B.

Volltext

Safe, Efficient, and Reproducible Gene Therapy of the Brain in the Dog Models of Sanfilippo and Hurler Syndromes von Ellinwood, N Matthew, Ausseil, Jérôme, Desmaris, Nathalie, Bigou, Stéphanie, Liu, Song, Jens, Jackie K, Snella, Elizabeth M, Mohammed, Eman EA, Thomson, Christopher B, Raoul, Sylvie, Joussemet, Béatrice, Roux, Françoise, Chérel, Yan, Lajat, Yaouen, Piraud, Monique, Benchaouir, Rachid, Hermening, Stephan, Petry, Harald, Froissart, Roseline, Tardieu, Marc, Ciron, Carine, Moullier, Philippe, Parkes, Jennifer, Kline, Karen L, Maire, Irène, Vanier, Marie-Thérèse, Heard, Jean-Michel, Colle, Marie-Anne

Volltext

Gene therapy for lysosomal storage diseases: the lessons and promise of animal models von Ellinwood, N. Matthew, Vite, Charles H., Haskins, Mark E.

Volltext