Computational Insights on the Potential of Some NSAIDs for Treating COVID-19: Priority Set and Lead Optimization von Abo Elmaaty, Ayman, Hamed, Mohammed I A, Ismail, Muhammad I, B Elkaeed, Eslam, S Abulkhair, Hamada, Khattab, Muhammad, Al-Karmalawy, Ahmed A

Volltext

Recent advancements of coumarin-based anticancer agents: An up-to-date review von Al-Warhi, Tarfah, Sabt, Ahmed, Elkaeed, Eslam B., Eldehna, Wagdy M.

Volltext

Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway von Taghour, Mohammed S, Elkady, Hazem, Eldehna, Wagdy M, El-Deeb, Nehal, Kenawy, Ahmed M, Elkaeed, Eslam B, Alsfouk, Bshra A, Alesawy, Mohamed S, Husein, Dalal Z, Metwaly, Ahmed M, Eissa, Ibrahim H

Volltext

Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects von Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Gobaara, Ibraheem M. M., Alsfouk, Bshra A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.

Volltext

Molecular Docking and Dynamics Simulation Revealed the Potential Inhibitory Activity of ACEIs Against SARS-CoV-2 Targeting the hACE2 Receptor von Al-Karmalawy, Ahmed A., Dahab, Mohammed A., Metwaly, Ahmed M., Elhady, Sameh S., Elkaeed, Eslam B., Eissa, Ibrahim H., Darwish, Khaled M.

Volltext

Integrated study of Quercetin as a potent SARS-CoV-2 RdRp inhibitor: Binding interactions, MD simulations, and In vitro assays von Metwaly, Ahmed M, El-Fakharany, Esmail M, Alsfouk, Aisha A, Ibrahim, Ibrahim M, Elkaeed, Eslam B, Eissa, Ibrahim H

Volltext

Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers von Elmetwally, Souad A., Saied, Khaled F., Eissa, Ibrahim H., Elkaeed, Eslam B.

Volltext

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies von Khalifa, Mohamed M., Al-Karmalawy, Ahmed A., Elkaeed, Eslam B., Nafie, Mohamed S., Tantawy, Mohamed A., Eissa, Ibrahim H., Mahdy, Hazem A.

Volltext

New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies von Elkady, Hazem, Elwan, Alaa, El-Mahdy, Hesham A., Doghish, Ahmed S., Ismail, Ahmed, Taghour, Mohammed S., Elkaeed, Eslam B., Eissa, Ibrahim H., Dahab, Mohammed A., Mahdy, Hazem A., Khalifa, Mohamed M.

Volltext

Anticancer derivative of the natural alkaloid, theobromine, inhibiting EGFR protein: Computer-aided drug discovery approach von Eissa, Ibrahim H, Yousef, Reda G, Elkaeed, Eslam B, Alsfouk, Aisha A, Husein, Dalal Z, Ibrahim, Ibrahim M, Alesawy, Mohamed S, Elkady, Hazem, Metwaly, Ahmed M

Volltext

Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico stu... von Taghour, Mohammed S., Elkady, Hazem, Eldehna, Wagdy M., El-Deeb, Nehal M., Kenawy, Ahmed M., Elkaeed, Eslam B., Alsfouk, Aisha A., Alesawy, Mohamed S., Metwaly, Ahmed M., Eissa, Ibrahim. H.

Volltext

In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro) von Alesawy, Mohamed S., Abdallah, Abdallah E., Taghour, Mohammed S., Elkaeed, Eslam B., H. Eissa, Ibrahim, Metwaly, Ahmed M.

Volltext

In Silico Screening of Semi-Synthesized Compounds as Potential Inhibitors for SARS-CoV-2 Papain-like Protease: Pharmacophoric Features, Molecular Docking, ADMET, Toxicity and DFT S... von Alesawy, Mohamed S, Elkaeed, Eslam B, Alsfouk, Aisha A, Metwaly, Ahmed M, Eissa, Ibrahim H

Volltext

Novel coumarin-6-sulfonamide-chalcone hybrids as glutathione transferase P1-1 inhibitors von Sabt, Ahmed, Kitsos, Stefanos, Ebaid, Manal S, Furlan, Veronika, Pantiora, Panagiota D, Tsolka, Magdalini, Elkaeed, Eslam B, Hamissa, Mohamed Farouk, Angelis, Nikolaos, Tsitsilonis, Ourania E, Papageorgiou, Anastassios C, Bren, Urban, Labrou, Nikolaos E

Volltext

In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10 von Eissa, Ibrahim H., Khalifa, Mohamed M., Elkaeed, Eslam B., Hafez, Elsayed E., Alsfouk, Aisha A., Metwaly, Ahmed M.

Volltext

New Anticancer Theobromine Derivative Targeting EGFRWT and EGFRT790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies von Elkaeed, Eslam B., Yousef, Reda G., Elkady, Hazem, Alsfouk, Aisha A., Husein, Dalal Z., Ibrahim, Ibrahim M., Metwaly, Ahmed M., Eissa, Ibrahim H.

Volltext

Discovery of new quinolines as potent colchicine binding site inhibitors: design, synthesis, docking studies, and anti-proliferative evaluation von Hagras, Mohamed, El Deeb, Moshira A., Elzahabi, Heba S. A., Elkaeed, Eslam B., Mehany, Ahmed B. M., Eissa, Ibrahim H.

Volltext

( E )- N -(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-... von Yousef, Reda G, Elkady, Hazem, Elkaeed, Eslam B, Gobaara, Ibraheem M M, Al-Ghulikah, Hanan A, Husein, Dalal Z, Ibrahim, Ibrahim M, Metwaly, Ahmed M, Eissa, Ibrahim H

Volltext

New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies von Gaber, Ahmed A, Sobhy, Mohamed, Turky, Abdallah, Eldehna, Wagdy M, El-Sebaey, Samiha A, El-Metwally, Souad A, El-Naggar, Abeer M, Ibrahim, Ibrahim M, Elkaeed, Eslam B, Metwaly, Ahmed M, Eissa, Ibrahim H

Volltext

2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling von Shaldam, Moataz A., Hendrychová, Denisa, El-Haggar, Radwan, Vojáčková, Veronika, Majrashi, Taghreed A., Elkaeed, Eslam B., Masurier, Nicolas, Kryštof, Vladimír, Tawfik, Haytham O., Eldehna, Wagdy M.

Volltext