Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications von Lei, Xin Gen, Zhu, Jian-Hong, Cheng, Wen-Hsing, Bao, Yongping, Ho, Ye-Shih, Reddi, Amit R, Holmgren, Arne, Arnér, Elias S J

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Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy von Stafford, WC, Peng, XX, Olofsson, MH, Zhang, XN, Luci, DK, Lu, L, Cheng, Q, Tresaugues, L, Dexheimer, TS, Coussens, NP, Augsten, M, Ahlzen, HSM, Orwar, O, Ostman, A, Stone-Elander, S, Maloney, DJ, Jadhav, A, Simeonov, A, Linder, S, Arner, ESJ

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Thioredoxin-related protein of 14 kDa is an efficient L-cystine reductase and S-denitrosylase von Pader, Irina, Sengupta, Rajib, Cebula, Marcus, Xu, Jianqiang, Lundberg, Jon O, Holmgren, Arne, Johansson, Katarina, Arnér, Elias S J

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Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target von Kuntz, Angela N, Davioud-Charvet, Elisabeth, Sayed, Ahmed A, Califf, Lindsay L, Dessolin, Jean, Arnér, Elias S J, Williams, David L

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Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically von Felber, Jan G., Poczka, Lena, Scholzen, Karoline C., Zeisel, Lukas, Maier, Martin S., Busker, Sander, Theisen, Ulrike, Brandstädter, Christina, Becker, Katja, Arnér, Elias S. J., Thorn-Seshold, Julia, Thorn-Seshold, Oliver

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Direct Observation of Methylmercury and Auranofin Binding to Selenocysteine in Thioredoxin Reductase von Pickering, Ingrid J, Cheng, Qing, Rengifo, Emérita Mendoza, Nehzati, Susan, Dolgova, Natalia V, Kroll, Thomas, Sokaras, Dimosthenis, George, Graham N, Arnér, Elias S. J

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Selenocysteine Insertion at a Predefined UAG Codon in a Release Factor 1 (RF1)-depleted Escherichia coli Host Strain Bypasses Species Barriers in Recombinant Selenoprotein Translat... von Cheng, Qing, Arnér, Elias S.J.

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NADPH-dependent and -independent disulfide reductase systems von Miller, Colin G., Holmgren, Arne, Arnér, Elias S.J., Schmidt, Edward E.

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Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells von Anestål, Karin, Prast-Nielsen, Stefanie, Cenas, Narimantas, Arnér, Elias S J

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Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif von Felber, Jan G, Zeisel, Lukas, Poczka, Lena, Scholzen, Karoline, Busker, Sander, Maier, Martin S, Theisen, Ulrike, Brandstädter, Christina, Becker, Katja, Arnér, Elias S. J, Thorn-Seshold, Julia, Thorn-Seshold, Oliver

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TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy von McLoughlin, Michael R., Orlicky, David J., Prigge, Justin R., Krishna, Pushya, Talago, Emily A., Cavigli, Ian R., Eriksson, Sofi, Miller, Colin G., Kundert, Jean A., Sayin, Volkan I., Sabol, Rachel A., Heinemann, Joshua, Brandenberger, Luke O., Iverson, Sonya V., Bothner, Brian, Papagiannakopoulos, Thales, Shearn, Colin T., Arnér, Elias S. J., Schmidt, Edward E.

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Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades von Dagnell, Markus, Cheng, Qing, Rizvi, Syed Husain Mustafa, Pace, Paul E., Boivin, Benoit, Winterbourn, Christine C., Arnér, Elias S.J.

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System-wide identification and prioritization of enzyme substrates by thermal analysis von Saei, Amir Ata, Beusch, Christian M., Sabatier, Pierre, Wells, Juan Astorga, Gharibi, Hassan, Meng, Zhaowei, Chernobrovkin, Alexey, Rodin, Sergey, Näreoja, Katja, Thorsell, Ann-Gerd, Karlberg, Tobias, Cheng, Qing, Lundström, Susanna L., Gaetani, Massimiliano, Végvári, Ákos, Arnér, Elias S. J., Schüler, Herwig, Zubarev, Roman A.

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Effects of selenite and chelating agents on mammalian thioredoxin reductase inhibited by mercury: implications for treatment of mercury poisoning von Carvalho, Cristina M.L, Lu, Jun, Zhang, Xu, Arnér, Elias S.J, Holmgren, Arne

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Identification and targeting of selective vulnerability rendered by tamoxifen resistance von Singh, Madhurendra, Zhou, Xiaolei, Chen, Xinsong, Santos, Gema Sanz, Peuget, Sylvain, Cheng, Qing, Rihani, Ali, Arnér, Elias S. J, Hartman, Johan, Selivanova, Galina

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Selenoproteins—What unique properties can arise with selenocysteine in place of cysteine? von Arner, Elias S.J.

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Redox active motifs in selenoproteins von Li, Fei, Lutz, Patricia B., Pepelyayeva, Yuliya, Arnér, Elias S. J., Bayse, Craig A., Rozovsky, Sharon

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Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver von Eriksson, Sofi, Prigge, Justin R., Talago, Emily A., Arnér, Elias S.J., Schmidt, Edward E.

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Development of therapies for rare genetic disorders of GPX4: roadmap and opportunities von Cheff, Dorian M, Muotri, Alysson R, Stockwell, Brent R, Schmidt, Edward E, Ran, Qitao, Kartha, Reena V, Johnson, Simon C, Mittal, Plavi, Arnér, Elias S. J, Wigby, Kristen M, Hall, Matthew D, Ramesh, Sanath Kumar

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Selective Evaluation of Thioredoxin Reductase Enzymatic Activities von Arnér, Elias S. J.

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