Repair-independent functions of DNA-PKcs protect irradiated cells from mitotic slippage and accelerated senescence von Liu, Yue, Efimova, Elena V, Ramamurthy, Aishwarya, Kron, Stephen J

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O-GlcNAcylation Enhances Double-Strand Break Repair, Promotes Cancer Cell Proliferation, and Prevents Therapy-Induced Senescence in Irradiated Tumors von Efimova, Elena V, Appelbe, Oliver K, Ricco, Natalia, Lee, Steve S-Y, Liu, Yue, Wolfgeher, Donald J, Collins, Tamica N, Flor, Amy C, Ramamurthy, Aishwarya, Warrington, Sara, Bindokas, Vytautas P, Kron, Stephen J

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Mevalonate pathway activity as a determinant of radiation sensitivity in head and neck cancer von Ricco, Natalia, Flor, Amy, Wolfgeher, Don, Efimova, Elena V., Ramamurthy, Aishwarya, Appelbe, Oliver K., Brinkman, Jacqueline, Truman, Andrew W., Spiotto, Michael T., Kron, Stephen J.

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Poly(ADP-Ribose) Polymerase Inhibitor Induces Accelerated Senescence in Irradiated Breast Cancer Cells and Tumors von EFIMOVA, Elena V, MAUCERI, Helena J, KRON, Stephen J, WEICHSELBAUM, Ralph R, GOLDEN, Daniel W, LABAY, Edwardine, BINDOKAS, Vytautas P, DARGA, Thomas E, CHAKRABORTY, Chaitali, CAMILO BARRETO-ANDRADE, Juan, CRAWLEY, Clayton, SUTTON, Harold G

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Signal transducer and activator of transcription 1 regulates both cytotoxic and prosurvival functions in tumor cells von KHODAREV, Nikolai N, MINN, Andy J, EFIMOVA, Elena V, DARGA, Thomas E, LABAY, Edwardine, BECKETT, Michael, MAUCERI, Helena J, ROIZMAN, Bernard, WEICHSELBAUM, Ralph R

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Dynamic color-coded fluorescence imaging of the cell-cycle phase, mitosis, and apoptosis demonstrates how caffeine modulates cisplatinum efficacy von Miwa, Shinji, Yano, Shuya, Tome, Yasunori, Sugimoto, Naotoshi, Hiroshima, Yukihiko, Uehara, Fuminari, Mii, Sumiyuki, Kimura, Hiroaki, Hayashi, Katsuhiro, Efimova, Elena V., Fujiwara, Toshiyoshi, Tsuchiya, Hiroyuki, Hoffman, Robert M.

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Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization von Liu, Yue, Betori, Rick C., Pagacz, Joanna, Frost, Grant B., Efimova, Elena V., Wu, Ding, Wolfgeher, Donald J., Bryan, Tracy M., Cohen, Scott B., Scheidt, Karl A., Kron, Stephen J.

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HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation von Efimova, Elena V, Ricco, Natalia, Labay, Edwardine, Mauceri, Helena J, Flor, Amy C, Ramamurthy, Aishwarya, Sutton, Harold G, Weichselbaum, Ralph R, Kron, Stephen J

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Linking Cancer Metabolism to DNA Repair and Accelerated Senescence von Efimova, Elena V, Takahashi, Satoe, Shamsi, Noumaan A, Wu, Ding, Labay, Edwardine, Ulanovskaya, Olesya A, Weichselbaum, Ralph R, Kozmin, Sergey A, Kron, Stephen J

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Radiation-inducible Immunotherapy for Cancer: Senescent Tumor Cells as a Cancer Vaccine von Meng, Yuru, Efimova, Elena V, Hamzeh, Khaled W, Darga, Thomas E, Mauceri, Helena J., Fu, Yang-Xin, Kron, Stephen J, Weichselbaum, Ralph R

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Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation von Barreto-Andrade, Juan Camilo, Efimova, Elena V, Mauceri, Helena J, Beckett, Michael A, Sutton, Harold G, Darga, Thomas E, Vokes, Everett E, Posner, Mitchell C, Kron, Stephen J, Weichselbaum, Ralph R

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Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers von Labay, Edwardine, Mauceri, Helena J, Efimova, Elena V, Flor, Amy C, Sutton, Harold G, Kron, Stephen J, Weichselbaum, Ralph R

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Imaging UVC-induced DNA damage response in models of minimal cancer von Miwa, Shinji, Yano, Shuya, Hiroshima, Yukihiko, Tome, Yasunori, Uehara, Fuminari, Mii, Sumiyuki, Efimova, Elena V., Kimura, Hiroaki, Hayashi, Katsuhiro, Tsuchiya, Hiroyuki, Hoffman, Robert M.

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Prescribed Versus Taken Polypharmacy and Drug-Drug Interactions in Older Cardiovascular Patients during the COVID-19 Pandemic: Observational Cross-Sectional Analytical Study von Anfinogenova, Nina D, Novikova, Oksana M, Trubacheva, Irina A, Efimova, Elena V, Chesalov, Nazary P, Ussov, Wladimir Y, Maksimova, Aleksandra S, Shelkovnikova, Tatiana A, Ryumshina, Nadezhda I, Stepanov, Vadim A, Popov, Sergey V, Repin, Alexey N

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Clinical Significance and Patterns of Potential Drug-Drug Interactions in Cardiovascular Patients: Focus on Low-Dose Aspirin and Angiotensin-Converting Enzyme Inhibitors von Anfinogenova, Nina D, Stepanov, Vadim A, Chernyavsky, Alexander M, Karpov, Rostislav S, Efimova, Elena V, Novikova, Oksana M, Trubacheva, Irina A, Falkovskaya, Alla Y, Maksimova, Aleksandra S, Ryumshina, Nadezhda I, Shelkovnikova, Tatiana A, Ussov, Wladimir Y, Vaizova, Olga E, Popov, Sergey V, Repin, Alexei N

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Real-Time Fluorescence Imaging of the DNA Damage Repair Response During Mitosis von Miwa, Shinji, Yano, Shuya, Yamamoto, Mako, Matsumoto, Yasunori, Uehara, Fuminari, Hiroshima, Yukihiko, Toneri, Makoto, Murakami, Takashi, Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Efimova, Elena V., Tsuchiya, Hiroyuki, Hoffman, Robert M.

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Single cell time-lapse imaging of focus formation by the DNA damage-response protein 53BP1 after UVC irradiation of human pancreatic cancer cells von Miwa, Shinji, Tome, Yasunori, Yano, Shuya, Hiroshima, Yukihiko, Uehara, Fuminari, Mii, Sumiyuki, Kimura, Hiroaki, Hayashi, Katsuhiro, Tsuchiya, Hiroyuki, Bouvet, Michael, Efimova, Elena V, Hoffman, Robert M

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Efficacy of the Combination of a PARP Inhibitor and UVC on Cancer Cells as Imaged by Focus Formation by the DNA Repair-related Protein 53BP1 Linked to Green Fluorescent Protein von Tome, Yasunori, Uehara, Fuminari, Miwa, Shinji, Yano, Shuya, Mii, Sumiyuki, Efimova, Elena V, Bouvet, Michael, Kimura, Hiroaki, Tsuchiya, Hiroyuki, Kanaya, Fuminori, Hoffman, Robert M

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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling von Efimova, Elena V., Liang, Hua, Pitroda, Sean P., Labay, Edwardine, Darga, Thomas E., Levina, Vera, Lokshin, Anna, Roizman, Bernard, Weichselbaum, Ralph R., Khodarev, Nikolai N.

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IG20 (MADD splice variant-5), a proapoptotic protein, interacts with DR4 DR5 and enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the DISC von Ramaswamy, Madhu, Efimova, Elena V, Martinez, Osvaldo, Mulherkar, Nirupama U, Singh, Surya P, Prabhakar, Bellur S

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