Pneumolysin: Pathogenesis and Therapeutic Target von Nishimoto, Andrew T., Rosch, Jason W., Tuomanen, Elaine I.

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Streptococcus pneumoniae : Invasion and Inflammation von Loughran, Allister J, Orihuela, Carlos J, Tuomanen, Elaine I

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Dynamic capsule restructuring by the main pneumococcal autolysin LytA in response to the epithelium von Kietzman, Colin C., Gao, Geli, Mann, Beth, Myers, Lance, Tuomanen, Elaine I.

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Streptococcus pneumoniae translocates into the myocardium and forms unique microlesions that disrupt cardiac function von Brown, Armand O, Mann, Beth, Gao, Geli, Hankins, Jane S, Humann, Jessica, Giardina, Jonathan, Faverio, Paola, Restrepo, Marcos I, Halade, Ganesh V, Mortensen, Eric M, Lindsey, Merry L, Hanes, Martha, Happel, Kyle I, Nelson, Steve, Bagby, Gregory J, Lorent, Jose A, Cardinal, Pablo, Granados, Rosario, Esteban, Andres, LeSaux, Claude J, Tuomanen, Elaine I, Orihuela, Carlos J

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Control of virulence by small RNAs in Streptococcus pneumoniae von Mann, Beth, van Opijnen, Tim, Wang, Jianmin, Obert, Caroline, Wang, Yong-Dong, Carter, Robert, McGoldrick, Daniel J, Ridout, Granger, Camilli, Andrew, Tuomanen, Elaine I, Rosch, Jason W

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Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens von El Kasmi, Karim C, Qualls, Joseph E, Pesce, John T, Smith, Amber M, Thompson, Robert W, Henao-Tamayo, Marcela, Basaraba, Randall J, König, Till, Schleicher, Ulrike, Koo, Mi-Sun, Kaplan, Gilla, Fitzgerald, Katherine A, Tuomanen, Elaine I, Orme, Ian M, Kanneganti, Thirumala-Devi, Bogdan, Christian, Wynn, Thomas A, Murray, Peter J

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Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children von Tuomanen, Elaine I

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Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex von Mann, Beth, Crawford, Jeremy Chase, Reddy, Kavya, Lott, Josi, Youn, Yong Ha, Gao, Geli, Guy, Cliff, Chou, Ching-Heng, Darnell, Daniel, Trivedi, Sanchit, Bomme, Perrine, Loughran, Allister J, Thomas, Paul G, Han, Young-Goo, Tuomanen, Elaine I

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Tissue-Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis von Orihuela, Carlos J., Gao, Geli, Francis, Kevin P., Yu, Jun, Tuomanen, Elaine I.

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Broadly Protective Protein-Based Pneumococcal Vaccine Composed of Pneumolysin Toxoid—CbpA Peptide Recombinant Fusion Protein von Mann, Beth, Thornton, Justin, Heath, Richard, Wade, Kristin R., Tweten, Rodney K., Gao, Geli, Kasmi, Karim El, Jordan, John B., Mitrea, Diana M., Kriwacki, Richard, Maisonneuve, Jeff, Alderson, Mark, Tuomanen, Elaine I.

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Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System von MacCain, William J, Tuomanen, Elaine I

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Dissecting Bacterial Cell Wall Entry and Signaling in Eukaryotic Cells: an Actin-Dependent Pathway Parallels Platelet-Activating Factor Receptor-Mediated Endocytosis von Loh, Lip Nam, Gao, Geli, Tuomanen, Elaine I

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Multi-Valent Protein Hybrid Pneumococcal Vaccines: A Strategy for the Next Generation of Vaccines von Scott, Ninecia R, Mann, Beth, Tuomanen, Elaine I, Orihuela, Carlos J

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Genomic Analyses of Pneumococci from Children with Sickle Cell Disease Expose Host-Specific Bacterial Adaptations and Deficits in Current Interventions von Carter, Robert, Wolf, Joshua, van Opijnen, Tim, Muller, Martha, Obert, Caroline, Burnham, Corinna, Mann, Beth, Li, Yimei, Hayden, Randall T., Pestina, Tamara, Persons, Derek, Camilli, Andrew, Flynn, Patricia M., Tuomanen, Elaine I., Rosch, Jason W.

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AdcAII of Streptococcus pneumoniae Affects Pneumococcal Invasiveness von Brown, Lindsey R, Gunnell, Steven M, Cassella, Adam N, Keller, Lance E, Scherkenbach, Lisa A, Mann, Beth, Brown, Matthew W, Hill, Rebecca, Fitzkee, Nicholas C, Rosch, Jason W, Tuomanen, Elaine I, Thornton, Justin A

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Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease von Rosch, Jason W, Boyd, Angela R, Hinojosa, Ernesto, Pestina, Tamara, Hu, Yunming, Persons, Derek A, Orihuela, Carlos J, Tuomanen, Elaine I

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Toll-Like Receptor 2 Mediates Fatal Immunopathology in Mice During Treatment of Secondary Pneumococcal Pneumonia Following Influenza von Karlström, Åsa, Heston, Sarah M., Boyd, Kelli L., Tuomanen, Elaine I., McCullers, Jonathan A.

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Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster von Valentino, Michael D., McGuire, Abigail Manson, Rosch, Jason W., Bispo, Paulo J. M., Burnham, Corinna, Sanfilippo, Christine M., Carter, Robert A., Zegans, Michael E., Beall, Bernard, Earl, Ashlee M., Tuomanen, Elaine I., Morris, Timothy W., Haas, Wolfgang, Gilmore, Michael S.

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Identification of a Candidate Streptococcus pneumoniae Core Genome and Regions of Diversity Correlated with Invasive Pneumococcal Disease von Obert, Caroline, Sublett, Jack, Kaushal, Deepak, Hinojosa, Ernesto, Barton, Theresa, Tuomanen, Elaine I, Orihuela, Carlos J

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Microarray Analysis of Pneumococcal Gene Expression during Invasive Disease von ORIHUELA, Carlos J, RADIN, Jana N, SUBLETT, Jack E, GAO, Geli, KAUSHAL, Deepak, TUOMANEN, Elaine I

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