RGS12 is a novel tumor suppressor in osteosarcoma that inhibits YAP-TEAD1-Ezrin signaling von Li, Yang, Liu, Min, Yang, Shuting, Fuller, Ashley M., Karin Eisinger-Mathason, T. S., Yang, Shuying

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Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy von Li, Jinyang, Byrne, Katelyn T., Yan, Fangxue, Yamazoe, Taiji, Chen, Zeyu, Baslan, Timour, Richman, Lee P., Lin, Jeffrey H., Sun, Yu H., Rech, Andrew J., Balli, David, Hay, Ceire A., Sela, Yogev, Merrell, Allyson J., Liudahl, Shannon M., Gordon, Naomi, Norgard, Robert J., Yuan, Salina, Yu, Sixiang, Chao, Timothy, Ye, Shuai, Eisinger-Mathason, T.S. Karin, Faryabi, Robert B., Tobias, John W., Lowe, Scott W., Coussens, Lisa M., Wherry, E. John, Vonderheide, Robert H., Stanger, Ben Z.

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Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression von Devalaraja, Samir, To, Tsun Ki Jerrick, Folkert, Ian W., Natesan, Ramakrishnan, Alam, Md Zahidul, Li, Minghong, Tada, Yuma, Budagyan, Konstantin, Dang, Mai T., Zhai, Li, Lobel, Graham P., Ciotti, Gabrielle E., Eisinger-Mathason, T.S. Karin, Asangani, Irfan A., Weber, Kristy, Simon, M. Celeste, Haldar, Malay

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A Feedback Loop between Hypoxia and Matrix Stress Relaxation Increases Oxygen-Axis Migration and Metastasis in Sarcoma von Lewis, Daniel M, Pruitt, Hawley, Jain, Nupur, Ciccaglione, Mark, McCaffery, J Michael, Xia, Zhiyong, Weber, Kristy, Eisinger-Mathason, T S Karin, Gerecht, Sharon

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Collagen VI deposition mediates stromal T cell trapping through inhibition of T cell motility in the prostate tumor microenvironment von Pruitt, Hawley C., Guan, Ya, Liu, Hudson, Carey, Alexis E, Brennen, W. Nathaniel, Lu, Jiayun, Joshu, Corrine, Weeraratna, Ashani, Lotan, Tamara L., Karin Eisinger-Mathason, T.S., Gerecht, Sharon

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Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis von Eisinger-Mathason, T S Karin, Zhang, Minsi, Qiu, Qiong, Skuli, Nicolas, Nakazawa, Michael S, Karakasheva, Tatiana, Mucaj, Vera, Shay, Jessica E S, Stangenberg, Lars, Sadri, Navid, Puré, Ellen, Yoon, Sam S, Kirsch, David G, Simon, M Celeste

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Targeting the Hippo pathway: Clinical implications and therapeutics von Ye, Shuai, Eisinger-Mathason, T.S. Karin

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TGF beta and Hippo Pathways Cooperate to Enhance Sarcomagenesis and Metastasis through the Hyaluronan-Mediated Motility Receptor (HMMR) von Ye, Shuai, Liu, Ying, Fuller, Ashley M., Katti, Rohan, Ciotti, Gabrielle E., Chor, Susan, Alam, Md. Zahidul, Devalaraja, Samir, Lorent, Kristin, Weber, Kristy, Haldar, Malay, Pack, Michael A., Eisinger-Mathason, T. S. Karin

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Intratumoral oxygen gradients mediate sarcoma cell invasion von Lewis, Daniel M., Park, Kyung Min, Tang, Vitor, Xu, Yu, Pak, Koreana, Eisinger-Mathason, T. S. Karin, Simon, M. Celeste, Gerecht, Sharon

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Sustained activation of the HER1-ERK1/2-RSK signaling pathway controls myoepithelial cell fate in human mammary tissue von Pasic, Lejla, Eisinger-Mathason, T S Karin, Velayudhan, Bisi T, Moskaluk, Christopher A, Brenin, David R, Macara, Ian G, Lannigan, Deborah A

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Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1 von Deng, Qu, Natesan, Ramakrishnan, Cidre-Aranaz, Florencia, Arif, Shehbeel, Liu, Ying, Rasool, Reyaz ur, Wang, Pei, Mitchell-Velasquez, Erick, Das, Chandan Kanta, Vinca, Endrit, Cramer, Zvi, Grohar, Patrick J., Chou, Margaret, Kumar-Sinha, Chandan, Weber, Kristy, Eisinger-Mathason, T.S. Karin, Grillet, Nicolas, Grünewald, Thomas, Asangani, Irfan A.

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Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis von Eisinger-Mathason, T. S. Karin, Mucaj, Vera, Biju, Kevin M., Nakazawa, Michael S., Gohil, Mercy, Cash, Timothy P., Yoon, Sam S., Skuli, Nicolas, Park, Kyung Min, Gerecht, Sharon, Simon, M. Celeste

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Codependent Functions of RSK2 and the Apoptosis-Promoting Factor TIA-1 in Stress Granule Assembly and Cell Survival von Eisinger-Mathason, T.S. Karin, Andrade, Josefa, Groehler, Angela L., Clark, David E., Muratore-Schroeder, Tara L., Pasic, Lejla, Smith, Jeffrey A., Shabanowitz, Jeffrey, Hunt, Donald F., Macara, Ian G., Lannigan, Deborah A.

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Context Matters: Response Heterogeneity to Collagen-Targeting Approaches in Desmoplastic Cancers von Fuller, Ashley M., Eisinger-Mathason, Tzipora S. Karin

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Overcoming evasive resistance from vascular endothelial growth factor a inhibition in sarcomas by genetic or pharmacologic targeting of hypoxia‐inducible factor 1α von Kim, Yeo‐Jung, Lee, Hae‐June, Kim, Tae‐Min, Eisinger‐Mathason, T.S. Karin, Zhang, Alexia Y., Schmidt, Benjamin, Karl, Daniel L., Nakazawa, Michael S., Park, Peter J., Simon, M. Celeste, Yoon, Sam S.

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Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth von Nakazawa, Michael S., Eisinger-Mathason, T. S. Karin, Sadri, Navid, Ochocki, Joshua D., Gade, Terence P. F., Amin, Ruchi K., Simon, M. Celeste

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YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis von Ye, Shuai, Lawlor, Matthew A, Rivera-Reyes, Adrian, Egolf, Shaun, Chor, Susan, Pak, Koreana, Ciotti, Gabrielle E, Lee, Avery C, Marino, Gloria E, Shah, Jennifer, Niedzwicki, David, Weber, Kristy, Park, Paul M C, Alam, Md Zahidul, Grazioli, Alison, Haldar, Malay, Xu, Mousheng, Perry, Jennifer A, Qi, Jun, Eisinger-Mathason, T S Karin

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YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma von Rivera-Reyes, Adrian, Ye, Shuai, E. Marino, Gloria, Egolf, Shaun, E. Ciotti, Gabrielle, Chor, Susan, Liu, Ying, Posimo, Jessica M., Park, Paul M. C., Pak, Koreana, Babichev, Yael, Sostre-Colón, Jaimarie, Tameire, Feven, Leli, Nektaria Maria, Koumenis, Constantinos, C. Brady, Donita, Mancuso, Anthony, Weber, Kristy, Gladdy, Rebecca, Qi, Jun, Eisinger-Mathason, T. S. Karin

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Comparative oncology reveals DNMT3B as a molecular vulnerability in undifferentiated pleomorphic sarcoma von Fuller, Ashley M., DeVine, Ann, Murazzi, Ileana, Mason, Nicola J., Weber, Kristy, Eisinger-Mathason, T. S. Karin

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Cancer research needs better databases von Eisinger-Mathason, T. S. Karin

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