IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization von Eissmann, Moritz F., Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R., Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D., Hibbs, Margaret L., Boussioutas, Alex, Grimbaldeston, Michele A., Buchert, Michael, O’Donoghue, Robert J. J., Masson, Frederick, Ernst, Matthias

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IL33 and Mast Cells-The Key Regulators of Immune Responses in Gastrointestinal Cancers? von Eissmann, Moritz F., Buchert, Michael, Ernst, Matthias

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A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development von O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael

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Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model von Thiem, Stefan, Eissmann, Moritz F, Elzer, Joachim, Jonas, Anna, Putoczki, Tracy L, Poh, Ashleigh, Nguyen, Paul, Preaudet, Adele, Flanagan, Dustin, Vincan, Elizabeth, Waring, Paul, Buchert, Michael, Jarnicki, Andrew, Ernst, Matthias

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Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines von Huber, Anne, Allam, Amr H., Dijkstra, Christine, Thiem, Stefan, Huynh, Jennifer, Poh, Ashleigh R., Konecnik, Joshua, Jacob, Saumya P., Busuttil, Rita, Liao, Yang, Chisanga, David, Shi, Wei, Alorro, Mariah G., Forrow, Stephen, Tauriello, Daniele V.F., Batlle, Eduard, Boussioutas, Alex, Williams, David S., Buchert, Michael, Ernst, Matthias, Eissmann, Moritz F.

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Generation of gene-of-interest knockouts in murine organoids using CRISPR-Cas9 von Huber, Anne, Dijkstra, Christine, Ernst, Matthias, Eissmann, Moritz F.

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Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice von Poh, Ashleigh R., Dwyer, Amy R., Eissmann, Moritz F., Chand, Ashwini L., Baloyan, David, Boon, Louis, Murrey, Michael W., Whitehead, Lachlan, O'Brien, Megan, Lowell, Clifford A., Putoczki, Tracy L., Pixley, Fiona J., O'Donoghue, Robert J. J., Ernst, Matthias

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Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages von Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O'Brien, Megan, Poh, Ashleigh R, Ernst, Matthias

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Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving SRC Sign... von Zhang, Xing, Soutto, Mohammed, Chen, Zheng, Bhat, Nadeem, Zhu, Shoumin, Eissmann, Moritz F., Ernst, Matthias, Lu, Heng, Peng, Dunfa, Xu, Zekuan, El-Rifai, Wael

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Host IL11 Signaling Suppresses CD4+ T cell-Mediated Antitumor Responses to Colon Cancer in Mice von Huynh, Jennifer, Baloyan, David, Chisanga, David, Shi, Wei, O'Brien, Megan, Afshar-Sterle, Shoukat, Alorro, Mariah, Pang, Lokman, Williams, David S., Parslow, Adam C., Thilakasiri, Pathum, Eissmann, Moritz F., Boon, Louis, Masson, Frederick, Chand, Ashwini L., Ernst, Matthias

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EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis von Reehorst, Camilla M., Nightingale, Rebecca, Luk, Ian Y., Jenkins, Laura, Koentgen, Frank, Williams, David S., Darido, Charbel, Tan, Fiona, Anderton, Holly, Chopin, Michael, Schoffer, Kael, Eissmann, Moritz F., Buchert, Michael, Mouradov, Dmitri, Sieber, Oliver M., Ernst, Matthias, Dhillon, Amardeep S., Mariadason, John M.

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DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression von Afshar-Sterle, Shoukat, Carli, Annalisa L E, O'Keefe, Ryan, Tse, Janson, Fischer, Stefanie, Azimpour, Alexander I, Baloyan, David, Elias, Lena, Thilakasiri, Pathum, Patel, Onisha, Ferguson, Fleur M, Eissmann, Moritz F, Chand, Ashwini L, Gray, Nathanael S, Busuttil, Rita, Boussioutas, Alex, Lucet, Isabelle S, Ernst, Matthias, Buchert, Michael

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Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ-Dependent Manner von Eissmann, Moritz F, Dijkstra, Christine, Wouters, Merridee A, Baloyan, David, Mouradov, Dmitri, Nguyen, Paul M, Davalos-Salas, Mercedes, Putoczki, Tracy L, Sieber, Oliver M, Mariadason, John M, Ernst, Matthias, Masson, Frederick

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Inducible gene modification in the gastric epithelium of Tff1-CreERT2, Tff2-rtTA, Tff3-luc mice von Thiem, Stefan, Eissmann, Moritz F., Stuart, Emma, Elzer, Joachim, Jonas, Anna, Buchert, Michael, Ernst, Matthias

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Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration von Phesse, Toby J, Buchert, Michael, Stuart, Emma, Flanagan, Dustin J, Faux, Maree, Afshar-Sterle, Shoukat, Walker, Francesca, Zhang, Hui-Hua, Nowell, Cameron J, Jorissen, Robert, Tan, Chin Wee, Hirokawa, Yumiko, Eissmann, Moritz F, Poh, Ashleigh R, Malaterre, Jordane, Pearson, Helen B, Kirsch, David G, Provero, Paolo, Poli, Valeria, Ramsay, Robert G, Sieber, Oliver, Burgess, Antony W, Huszar, Dennis, Vincan, Elizabeth, Ernst, Matthias

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Generation of an inducible mouse model to reversibly silence Stat3 von Alorro, Mariah G., Pierce, Thomas P., Eissmann, Moritz F., Dijkstra, Christine, Dickins, Ross A., Ernst, Matthias, Buchert, Michael, Masson, Frederic

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Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3 von Thilakasiri, Pathum, O'Keefe, Ryan N, To, Sarah Q, Chisanga, David, Eissmann, Moritz F, Carli, Annalisa LE, Duscio, Belinda, Baloyan, David, Dmello, Rhynelle S, Williams, David, Mariadason, John, Poh, Ashleigh R, Pal, Bhupinder, Kile, Benjamin T, Vissers, Joseph Ha, Harvey, Kieran F, Buchert, Michael, Shi, Wei, Ernst, Matthias, Chand, Ashwini L

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Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving Steroid... von Zhang, Xing, Soutto, Mohammed, Chen, Zheng, Bhat, Nadeem, Zhu, Shoumin, Eissmann, Moritz F., Ernst, Matthias, Lu, Heng, Peng, Dunfa, Xu, Zekuan, El-Rifai, Wael

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EHF ensures epithelial homeostasis von Reehorst, Camilla M., Nightingale, Rebecca, Luk, Ian Y., Jenkins, Laura, Koentgen, Frank, Williams, David S., Darido, Charbel, Tan, Fiona, Anderton, Holly, Chopin, Michael, Schoffer, Kael, Eissmann, Moritz F., Buchert, Michael, Mouradov, Dmitri, Sieber, Oliver M., Ernst, Matthias, Dhillon, Amardeep S., Mariadason, John M.

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Tumor Growth Remains Refractory to IMyc/I Ablation in Host Macrophages von Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O’Brien, Megan, Poh, Ashleigh R, Ernst, Matthias

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