Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo von Haidar, Samer, Ehmer, Peter B., Barassin, Stephan, Batzl-Hartmann, Christine, Hartmann, Rolf W.

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Synthesis and Evaluation of Novel Steroidal Oxime Inhibitors of P450 17 (17α-Hydroxylase/C17−20-Lyase) and 5α-Reductase Types 1 and 2 von Hartmann, Rolf W, Hector, Markus, Haidar, Samer, Ehmer, Peter B, Reichert, Wolfgang, Jose, Joachim

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Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,20-lyase (P450c17) by coexpression of P450c17 with NADPH-cytochrome-P450-reduc... von EHMER, Peter B, JOSE, Joachim, HARTMANN, Rolf W

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Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinan... von Hutschenreuter, Tilman U., Ehmer, Peter B., Hartmann, Rolf W.

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Development of a test system for inhibitors of human aldosterone synthase (CYP11B2): screening in fission yeast and evaluation of selectivity in V79 cells von Ehmer, Peter B, Bureik, Matthias, Bernhardt, Rita, Müller, Ursula, Hartmann, Rolf W

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Discovery of selective CYP11B2 (aldosterone synthase) inhibitors for the therapy of congestive heart failure and myocardial fibrosis von Hartmann, Rolf W., Müller, Ursula, Ehmer, Peter B.

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Simultaneous measurement of metabolic stability and metabolite identification of 7-methoxymethylthiazolo[3,2-a]pyrimidin-5-one derivatives in human liver microsomes using liquid ch... von Kantharaj, E., Ehmer, Peter B., Tuytelaars, An, Vlaslaer, Anne Van, Mackie, Claire, Gilissen, Ron A. H. J.

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Novel steroidal pyrimidyl inhibitors of P450 17 (17α-hydroxylase/C17-20-lyase) von Haidar, Samer, Ehmer, Peter B., Hartmann, Rolf W.

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The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore the in vitro metabolism of cyanoalkyl piperidine derivatives von Kantharaj, E., Ehmer, Peter B., De Wagter, Katie, Tuytelaars, An, Proost, Pascale E. A., Mackie, Claire, Gilissen, Ron A. H. J.

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Enantiomeric resolution of some human aldosterone synthase [CYP 11 B2] inhibitors on derivatized polysaccharide chiral stationary phases von Aboul-Enein, Hassan Y., Hefnawy, Mohamed M., Ehmer, Peter B., Hartmann, Rolf W.

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Inhibition of CYP 17, a New Strategy for the Treatment of Prostate Cancer von Hartmann, Rolf W., Ehmer, Peter B., Haidar, Samer, Hector, Markus, Jose, Joachim, Klein, Christian D. P., Seidel, Stefanie B., Sergejew, Tom F., Wachall, Bertil G., Wächter, Gerald A., Zhuang, Yan

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Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo von Haidar, Samer, Ehmer, Peter B, Barassin, Stephan, Batzl-Hartmann, Christine, Hartmann, Rolf W

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Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C17,20-lyase (P450cl7) by coexpression of P450cl7 with NADPH-cytochrome-P450-reduc... von Ehmer, Peter B., Jose, Joachim, Hartmann, Rolf W.

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Development of a simple and rapid assay for the evaluation of inhibitors of human 17α-hydroxylase-C 17,20-lyase (P450cl7) by coexpression of P450cl7 with NADPH-cytochrome-P450-redu... von Ehmer, Peter B., Jose, Joachim, Hartmann, Rolf W.

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The use of liquid chromatography-atmospheric pressure chemical ionization mass spectrometry to explore thein vitro metabolism of cyanoalkyl piperidine derivatives von Kantharaj, E., Ehmer, Peter B., De Wagter, Katie, Tuytelaars, An, Proost, Pascale E. A., Mackie, Claire, Gilissen, Ron A. H. J.

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ChemInform Abstract: Novel Steroidal Pyrimidyl Inhibitors of P450 17 (17α-Hydroxylase/C17-20-lyase) von Haidar, Samer, Ehmer, Peter B., Hartmann, Rolf W.

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Immunodeficiency at the start of combination antiretroviral therapy in low-, middle-, and high-income countries von Avila, Dorita, Althoff, Keri N, Mugglin, Catrina, Wools-Kaloustian, Kara, Koller, Manuel, Dabis, François, Nash, Denis, Gsponer, Thomas, Sungkanuparph, Somnuek, McGowan, Catherine, May, Margaret, Cooper, David, Chimbetete, Cleophas, Wolff, Marcelo, Collier, Ann, McManus, Hamish, Davies, Mary-Ann, Costagliola, Dominique, Crabtree-Ramirez, Brenda, Chaiwarith, Romanee, Cescon, Angela, Cornell, Morna, Diero, Lameck, Phanuphak, Praphan, Sawadogo, Adrien, Ehmer, Jochen, Eholie, Serge P, Li, Patrick C K, Fox, Matthew P, Gandhi, Neel R, González, Elsa, Lee, Christopher K C, Hoffmann, Christopher J, Kambugu, Andrew, Keiser, Olivia, Ditangco, Rossana, Prozesky, Hans, Lampe, Fiona, Kumarasamy, Nagalingeswaran, Kitahata, Mari, Lugina, Emmanuel, Lyamuya, Rita, Vonthanak, Saphonn, Fink, Valeria, d'Arminio Monforte, Antonella, Luz, Paula Mendes, Chen, Yi-Ming A, Minga, Albert, Casabona, Jordi, Mwango, Albert, Choi, Jun Y, Newell, Marie-Louise, Bukusi, Elizabeth A, Ngonyani, Kapella, Merati, Tuti P, Otieno, Juliana, Bosco, Mwebesa B, Phiri, Sam, Ng, Oon T, Anastos, Kathryn, Rockstroh, Jürgen, Santos, Ignacio, Oka, Shinichi, Somi, Geoffrey, Stephan, Christoph, Teira, Ramon, Wabwire, Deo, Wandeler, Gilles, Boulle, Andrew, Reiss, Peter, Wood, Robin, Chi, Benjamin H, Williams, Carolyn, Sterne, Jonathan A, Egger, Matthias

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Analysis of CpG dinucleotide frequency in relationship to translational reading frame suggests a class of genes in which mutation of this dinucleotide is asymmetric with respect to... von Leader, David P., Peter, Beate, Ehmer, Birgit

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