Modification of Keap1 Cysteine Residues by Sulforaphane von Hu, Chenqi, Eggler, Aimee L, Mesecar, Andrew D, van Breemen, Richard B

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Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1 von Eggler, Aimee L, Small, Evan, Hannink, Mark, Mesecar, Andrew D

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To each their own: Disparate abilities of Nrf2 activators to protect against various electrophilic and oxidative insults von Biesterveld, Laura M., Eggler, Aimee L.

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Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols von Sauerland, Max, Mertes, Ralf, Morozzi, Chiara, Eggler, Aimee L., Gamon, Luke F., Davies, Michael J.

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Molecular mechanisms of natural products in chemoprevention: Induction of cytoprotective enzymes by Nrf2 von Eggler, Aimee L, Gay, Kelly A, Mesecar, Andrew D

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Bioavailable Sulforaphane Quantitation in Plasma by LC–MS/MS Is Enhanced by Blocking Thiols von Grady, Rachel S., Traustadóttir, Tinna, Lagalante, Anthony F., Eggler, Aimee L.

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Assessment of air quality in the Philadelphia, Pennsylvania subway von Karim, Anjum Shahina, Malone, Maeve, Bruno, Alex, Eggler, Aimee L, Posner, Michael A, Shakya, Kabindra M

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Modifying Specific Cysteines of the Electrophile-Sensing Human Keap1 Protein Is Insufficient to Disrupt Binding to the Nrf2 Domain Neh2 von Eggler, Aimee L., Liu, Guowen, Pezzuto, John M., van Breemen, Richard B., Mesecar, Andrew D., Kustu, Sydney

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Comparison of human Nrf2 antibodies: A tale of two proteins von Kemmerer, Zachary A., Ader, Nicholas R., Mulroy, Sarah S., Eggler, Aimee L.

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Discovery, Synthesis, And Structure-Based Optimization of a Series of N‑(tert-Butyl)-2‑(N‑arylamido)-2-(pyridin-3-yl) Acetamides (ML188) as Potent Noncovalent Small Molecule Inhibi... von Jacobs, Jon, Grum-Tokars, Valerie, Zhou, Ya, Turlington, Mark, Saldanha, S. Adrian, Chase, Peter, Eggler, Aimee, Dawson, Eric S, Baez-Santos, Yahira M, Tomar, Sakshi, Mielech, Anna M, Baker, Susan C, Lindsley, Craig W, Hodder, Peter, Mesecar, Andrew, Stauffer, Shaun R

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Solving the Problem of Assessing Synergy and Antagonism for Non-Traditional Dosing Curve Compounds Using the DE/ZI Method: Application to Nrf2 Activators von Repash, Elizabeth M., Pensabene, Kaitlin M., Palenchar, Peter M., Eggler, Aimee L.

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Sites of Alkylation of Human Keap1 by Natural Chemoprevention Agents von Luo, Yan, Eggler, Aimee L., Liu, Dongting, Liu, Guowen, Mesecar, Andrew D., van Breemen, Richard B.

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Acute Oxidative Stress Can Paradoxically Suppress Human NRF2 Protein Synthesis by Inhibiting Global Protein Translation von Pensabene, Kaitlin M, LaMorte, Joseph, Allender, Amanda E, Wehr, Janessa, Kaur, Prabhjot, Savage, Matthew, Eggler, Aimee L

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Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accu... von Bauman, Bradly M., Jeong, Chang, Savage, Matthew, Briker, Anna L., Janigian, Nicholas G., Nguyen, Linda L., Kemmerer, Zachary A., Eggler, Aimee L.

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Identification of the Highly Reactive Cysteine 151 in the Chemopreventive Agent-Sensor Keap1 Protein is Method-Dependent von Eggler, Aimee L, Luo, Yan, van Breemen, Richard B, Mesecar, Andrew D

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Prospective Type 1 and Type 2 Disulfides of Keap1 Protein von Holland, Ryan, Hawkins, Arie E, Eggler, Aimee L, Mesecar, Andrew D, Fabris, Daniele, Fishbein, James C

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Synergy of Nrf2‐Activating Electrophiles in Combination with the Nrf2‐Inhibitor KI696: A Model of Mechanistic Basis for Synergy von Allender, Amanda, Eggler, Aimee

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Xanthohumol Isolated from Humulus lupulus Inhibits Menadione-Induced DNA Damage through Induction of Quinone Reductase von Dietz, Birgit M, Kang, Young-Hwa, Liu, Guowen, Eggler, Aimee L, Yao, Ping, Chadwick, Lucas R, Pauli, Guido F, Farnsworth, Norman R, Mesecar, Andrew D, van Breemen, Richard B, Bolton, Judy L

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Screening for natural chemoprevention agents that modify human Keap1 von Hu, Chenqi, Nikolic, Dejan, Eggler, Aimee L., Mesecar, Andrew D., van Breemen, Richard B.

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Quantitating Nrf2-regulated cytoprotective proteins using an LC-MS/MS data-independent acquisition method von Sodiya, Ibukunoluwa, Eggler, Aimee, Lagalante, Anthony

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