Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53 von de Queiroz, Rafaela Muniz, Efe, Gizem, Guzman, Asja, Hashimoto, Naoko, Kawashima, Yusuke, Tanaka, Tomoaki, Rustgi, Anil K., Prives, Carol

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Rab11-FIP1 mediates epithelial-mesenchymal transition and invasion in esophageal cancer von Tang, Qiaosi, Lento, Ashley, Suzuki, Kensuke, Efe, Gizem, Karakasheva, Tatiana, Long, Apple, Giroux, Véronique, Islam, Mirazul, Wileyto, E Paul, Klein-Szanto, Andres J, Nakagawa, Hiroshi, Bass, Adam, Rustgi, Anil K

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Mutant p53 regulates Survivin to foster lung metastasis von Tang, Qiaosi, Efe, Gizem, Chiarella, Anna M., Leung, Jessica, Chen, Maoting, Yamazoe, Taiji, Su, Zhenyi, Pitarresi, Jason R., Li, Jinyang, Islam, Mirazul, Karakasheva, Tatiana, Klein-Szanto, Andres J., Pan, Samuel, Hu, Jianhua, Natsugoe, Shoji, Gu, Wei, Stanger, Ben Z., Wong, Kwok-K, Diehl, J. Alan, Bass, Adam J., Nakagawa, Hiroshi, Murphy, Maureen E., Rustgi, Anil K.

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MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy von Owyong, Mark, Chou, Jonathan, van den Bijgaart, Renske Je, Kong, Niwen, Efe, Gizem, Maynard, Carrie, Talmi-Frank, Dalit, Solomonov, Inna, Koopman, Charlotte, Hadler-Olsen, Elin, Headley, Mark, Lin, Charlene, Wang, Chih-Yang, Sagi, Irit, Werb, Zena, Plaks, Vicki

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Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer von Ko, Kyung-Pil, Zhang, Shengzhe, Huang, Yuanjian, Kim, Bongjun, Zou, Gengyi, Jun, Sohee, Zhang, Jie, Zhao, Yahui, Martin, Cecilia, Dunbar, Karen J., Efe, Gizem, Rustgi, Anil K., Nakagawa, Hiroshi, Zhang, Haiyang, Liu, Zhihua, Park, Jae-Il

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Overcoming Barriers of Age to Enhance Efficacy of Cancer Immunotherapy: The Clout of the Extracellular Matrix von Owyong, Mark, Efe, Gizem, Owyong, Michael, Abbasi, Aamna J, Sitarama, Vaishnavi, Plaks, Vicki

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Abstract PO-106: The extrinsic and modulatory effects of CSF-1/CSF-1R signaling in generating an immunosuppressive pancreatic cancer tumor microenvironment and promoting metastasis von Efe, Gizem, Suzuki, Kensuke, Pitarresi, Jason R., Chiarella, Anna M., Li, Alina L., Rustgi, Anil K.

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Do temperament characteristics of children affect waiting room preferences von Efe, Gizem, Yilmaz, Nagehan, Tüzüner, Tamer, Baygın, Ozgul, Wilson, Stephen, Panda, Anup Kumar

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p53 at the crossroads of tumor immunity von Efe, Gizem, Rustgi, Anil K, Prives, Carol

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Tu1201: THE ROLE OF PRRX1 IN REGULATING KRAS-DRIVEN PANCREATIC ACINAR TO DUCTAL METAPLASIA von Li, Alina L., Sugiura, Kensuke, Suzuki, Kensuke, Pitarresi, Jason R., Chiarella, Anna, Efe, Gizem, Chandwani, Rohit, Rustgi, Anil

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EP1095: ELUCIDATION OF MUTANT P53-MEDIATED MECHANISMS IN PROMOTING METASTATIC ESOPHAGEAL CANCER von Efe, Gizem, Tang, Qiaosi, Cruz-Acuna, Ricardo, Suzuki, Kensuke, Li, Alina, Gabre, Joel T., Sachdeva, Uma M., Rustgi, Anil

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Key Genetic Determinants Driving Esophageal Squamous Cell Carcinoma Initiation and Immune Evasion von Ko, Kyung-Pil, Huang, Yuanjian, Zhang, Shengzhe, Zou, Gengyi, Kim, Bongjun, Zhang, Jie, Jun, Sohee, Martin, Cecilia, Dunbar, Karen J., Efe, Gizem, Rustgi, Anil K., Nakagawa, Hiroshi, Park, Jae-Il

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Abstract PO-075: The elucidation of the role of Prrx1 for acinar to ductal metaplasia in response to acute injury of pancreas in the novel mouse models von Suzuki, Kensuke, Li, Alina, Pitarresi, Jason R., Chiarella, Anna M., Efe, Gizem, Sugiura, Kensuke, Chandwani, Rohit, Rustgi, Anil K.

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Standardized Reporter Systems for Purification and Imaging of Human Pluripotent Stem Cell-derived Motor Neurons and Other Cholinergic Cells von Garcia-Diaz, Alejandro, Efe, Gizem, Kabra, Khushbu, Patel, Achchhe, Lowry, Emily R., Shneider, Neil A., Corneo, Barbara, Wichterle, Hynek

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Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets von Cruz-Acuña, Ricardo, Kariuki, Secunda W, Sugiura, Kensuke, Karaiskos, Spyros, Plaster, Eleanor M, Loebel, Claudia, Efe, Gizem, Karakasheva, Tatiana, Gabre, Joel T, Hu, Jianhua, Burdick, Jason A, Rustgi, Anil K

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Tumor-Derived CCL5 Recruits Cancer-Associated Fibroblasts and Promotes Tumor Cell Proliferation in Esophageal Squamous Cell Carcinoma von Dunbar, Karen J, Karakasheva, Tatiana A, Tang, Qiaosi, Efe, Gizem, Lin, Eric W, Harris, Michael, Sahu, Varun, Sachdeva, Uma M, Hu, Jianhua, Klein-Szanto, Andres J, Henick, Brian, Diehl, J Alan, Nakagawa, Hiroshi, Rustgi, Anil K

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Simulating Selected Human Hormonal Pathways During a 24‐Hour Period and Its Implications for Aging Research von Garan, Steven A., Efe, Gizem, Cheung, Kevin, Khurramb, Maaz A., Brooks, George A.

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Using Knowledge-fused Differential Dependency Network (KDDN) simulation to exploit the link between cancer, aging, & metabolism von Gouw, Arvin M., Preecha, Andrew, Efe, Gizem, Barakat, Rita, Garan, Steve A., Brooks, George A.

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Abstract LB160: Mdm2 regulates metastasis and associated cellular processes through modulation of Sprouty4 in a p53-independent manner von de Queiroz, Rafaela Muniz, Efe, Gizem, Guzman, Asja, Hashimoto, Naoko, Kawashima, Yusuke, Tanaka, Tomoaki, Rustgi, Anil K., Prives, Carol

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Cancer Immunotherapy Getting Brainy: Visualizing the Distinctive CNS Metastatic Niche to Illuminate Therapeutic Resistance von Owyong, Mark, Hosseini-Nassab, Niloufar, Efe, Gizem, Honkala, Alexander, van den Bijgaart, Renske J.E., Plaks, Vicki, Smith, Bryan Ronain

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