Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV von Zofou, Denis, Ntie-Kang, Fidele, Sippl, Wolfgang, Efange, Simon M. N

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Spirofused tetrahydroisoquinoline-oxindole hybrids as a novel class of fast acting antimalarial agents with multiple modes of action von Efange, Noella M., Lobe, Maloba M. M., Keumoe, Rodrigue, Ayong, Lawrence, Efange, Simon M. N.

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AfroDb: a select highly potent and diverse natural product library from African medicinal plants von Ntie-Kang, Fidele, Zofou, Denis, Babiaka, Smith B, Meudom, Rolande, Scharfe, Michael, Lifongo, Lydia L, Mbah, James A, Mbaze, Luc Meva'a, Sippl, Wolfgang, Efange, Simon M N

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Structurally simple synthetic 1, 4-disubstituted piperidines with high selectivity for resistant Plasmodium falciparum von Ngemenya, Moses N, Abwenzoh, Grace Ntube, Ikome, Hermia Nalova, Zofou, Denis, Ntie-Kang, Fidele, Efange, Simon M N

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4-aroylpiperidines and 4-(α-hydroxyphenyl)piperidines as selective sigma-1 receptor ligands: synthesis, preliminary pharmacological evaluation and computational studies von Ikome, Hermia N., Ntie-Kang, Fidele, Ngemenya, Moses N., Tu, Zhude, Mach, Robert H., Efange, Simon M. N.

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Antiparasitic Sesquiterpenes from the Cameroonian Spice Scleria striatinux and Preliminary In Vitro and In Silico DMPK Assessment von Nyongbela, Kennedy D., Ntie-Kang, Fidele, Hoye, Thomas R., Efange, Simon M. N.

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Bioassay-guided discovery of antibacterial agents: in vitro screening of Peperomia vulcanica, Peperomia fernandopoioana and Scleria striatinux von Mbah, James A, Ngemenya, Moses N, Abawah, Ashime Louis, Babiaka, Smith B, Nubed, Lina N, Nyongbela, Kennedy D, Lemuh, Njimoh Dieudonne, Efange, Simon M N

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In vitro anti- Helicobacter pylori activity of extracts of selected medicinal plants from North West Cameroon von Ndip, Roland N., Malange Tarkang, Alertia E., Mbullah, Susan M., Luma, Henry N., Malongue, Agnes, Ndip, Lucy M., Nyongbela, Kennedy, Wirmum, Clare, Efange, Simon M.N.

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Spirofused Tetrahydroisoquinoline-Oxindole Hybrids (Spiroquindolones) as Potential Multitarget Antimalarial Agents: Preliminary Hit Optimization and Efficacy Evaluation in Mice von Efange, Noella M, Lobe, Maloba M M, Yamthe, Lauve R T, Pekam, Jeannette N M, Tarkang, Protus A, Ayong, Lawrence, Efange, Simon M N

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Synthesis and in Vitro Biological Evaluation of Carbonyl Group-Containing Inhibitors of Vesicular Acetylcholine Transporter von Efange, Simon M. N, Khare, Anil B, von Hohenberg, Krystyna, Mach, Robert H, Parsons, Stanley M, Tu, Zhude

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Okundoperoxide, a Bicyclic Cyclofarnesylsesquiterpene Endoperoxide from Scleria striatinux with Antiplasmodial Activity von Efange, Simon M. N, Brun, Reto, Wittlin, Sergio, Connolly, Joseph D, Hoye, Thomas R, McAkam, Thomas, Makolo, Felix L, Mbah, James A, Nelson, Dorian P, Nyongbela, Kennedy D, Wirmum, Clare K

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Isolation and Characterization of Sclerienone C from Scleria Striatinux von Nyongbela, Kennedy D., Makolo, Felix L., Hoye, Thomas R., Efange, Simon MN

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3′,4′-Dihydro-2′H-spiro[indoline-3,1′-isoquinolin]-2-ones as potential anti-cancer agents: synthesis and preliminary screening von Lobe, Maloba M. M., Efange, Simon M. N.

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ConMedNP: a natural product library from Central African medicinal plants for drug discovery von Ntie-Kang, Fidele, Onguéné, Pascal Amoa, Scharfe, Michael, Owono Owono, Luc C., Megnassan, Eugene, Mbaze, Luc Meva'a, Sippl, Wolfgang, Efange, Simon M. N.

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CamMedNP: building the Cameroonian 3D structural natural products database for virtual screening von Ntie-Kang, Fidele, Mbah, James A, Mbaze, Luc Meva'a, Lifongo, Lydia L, Scharfe, Michael, Hanna, Joelle Ngo, Cho-Ngwa, Fidelis, Onguéné, Pascal Amoa, Owono Owono, Luc C, Megnassan, Eugene, Sippl, Wolfgang, Efange, Simon M N

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How “drug-like” are naturally occurring anti-cancer compounds? von Ntie-Kang, Fidele, Lifongo, Lydia L., Judson, Philip N., Sippl, Wolfgang, Efange, Simon M. N.

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Synthesis and in Vitro and in Vivo Evaluation of 18F-Labeled Positron Emission Tomography (PET) Ligands for Imaging the Vesicular Acetylcholine Transporter von Tu, Zhude, Efange, Simon M. N, Xu, Jinbin, Li, Shihong, Jones, Lynne A, Parsons, Stanley M, Mach, Robert H

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Cameroonian medicinal plants: a bioactivity versus ethnobotanical survey and chemotaxonomic classification von Ntie-Kang, Fidele, Lifongo, Lydia Likowo, Mbaze, Luc Meva'a, Ekwelle, Nnange, Owono Owono, Luc C, Megnassan, Eugene, Judson, Philip N, Sippl, Wolfgang, Efange, Simon M N

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Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo[2.2.2]oct-7-enes von Passarella, Daniele, Favia, Raffaele, Giardini, Alessandra, Lesma, Giordano, Martinelli, Marisa, Silvani, Alessandra, Danieli, Bruno, Efange, Simon M.N, Mash, Deborah C

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1-Aryl-1,2,3,4-tetrahydroisoquinolines as potential antimalarials: synthesis, in vitro antiplasmodial activity and in silico pharmacokinetics evaluation von Hanna, Joelle Ngo, Ntie-Kang, Fidele, Kaiser, Marcel, Brun, Reto, Efange, Simon M. N.

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