Whole-exome sequencing efficiently detects rare mutations in autosomal recessive nonsyndromic hearing loss von Diaz-Horta, Oscar, Duman, Duygu, Foster, 2nd, Joseph, Sırmacı, Aslı, Gonzalez, Michael, Mahdieh, Nejat, Fotouhi, Nikou, Bonyadi, Mortaza, Cengiz, Filiz Başak, Menendez, Ibis, Ulloa, Rick H, Edwards, Yvonne J K, Züchner, Stephan, Blanton, Susan, Tekin, Mustafa

Volltext

The Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) oncogene is upregulated in cystic epithelial cells revealing a potential new target for polycystic kidney disease von Smith, Abigail O, Frantz, William Tyler, Preval, Kenley M, Edwards, Yvonne J K, Ceol, Craig J, Jonassen, Julie A, Pazour, Gregory J

Volltext

ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability von Reddi, Kiran Kumar, Chava, Suresh, Chabattula, Siva Chander, Edwards, Yvonne J. K., Singh, Kamaljeet, Gupta, Romi

Volltext

Comparative transcriptomics in human COPD reveals dysregulated genes uniquely expressed in ferrets von Hussain, Shah S, Edwards, Yvonne J K, Libby, Emily Falk, Stanford, Denise, Byzek, Stephen A, Sin, Don D, McDonald, Merry-Lynn, Raju, S Vamsee, Rowe, Steven M

Volltext

Highly conserved non-coding sequences are associated with vertebrate development von Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, Smith, Sarah F, North, Phil, Callaway, Heather, Kelly, Krys, Walter, Klaudia, Abnizova, Irina, Gilks, Walter, Edwards, Yvonne J K, Cooke, Julie E, Elgar, Greg

Volltext

Disruptor of telomeric silencing 1-like promotes ovarian cancer tumor growth by stimulating pro-tumorigenic metabolic pathways and blocking apoptosis von Chava, Suresh, Bugide, Suresh, Edwards, Yvonne J. K., Gupta, Romi

Volltext

Whole-Exome Sequencing Links a Variant in DHDDS to Retinitis Pigmentosa von Züchner, Stephan, Dallman, Julia, Wen, Rong, Beecham, Gary, Naj, Adam, Farooq, Amjad, Kohli, Martin A., Whitehead, Patrice L., Hulme, William, Konidari, Ioanna, Edwards, Yvonne J.K., Cai, Guiqing, Peter, Inga, Seo, David, Buxbaum, Joseph D., Haines, Jonathan L., Blanton, Susan, Young, Juan, Alfonso, Eduardo, Vance, Jeffery M., Lam, Byron L., Peričak-Vance, Margaret A.

Volltext

Challenges in whole exome sequencing: an example from hereditary deafness von Sirmaci, Asli, Edwards, Yvonne J K, Akay, Hatice, Tekin, Mustafa

Volltext

Identifying consensus disease pathways in Parkinson's disease using an integrative systems biology approach von Edwards, Yvonne J K, Beecham, Gary W, Scott, William K, Khuri, Sawsan, Bademci, Guney, Tekin, Demet, Martin, Eden R, Jiang, Zhijie, Mash, Deborah C, ffrench-Mullen, Jarlath, Pericak-Vance, Margaret A, Tsinoremas, Nicholas, Vance, Jeffery M

Volltext

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis von Sanchez-Gurmaches, Joan, Tang, Yuefeng, Jespersen, Naja Zenius, Wallace, Martina, Martinez Calejman, Camila, Gujja, Sharvari, Li, Huawei, Edwards, Yvonne J.K., Wolfrum, Christian, Metallo, Christian M., Nielsen, Søren, Scheele, Camilla, Guertin, David A.

Volltext

Comparison of three targeted enrichment strategies on the SOLiD sequencing platform von Hedges, Dale J, Guettouche, Toumy, Yang, Shan, Bademci, Guney, Diaz, Ashley, Andersen, Ashley, Hulme, William F, Linker, Sara, Mehta, Arpit, Edwards, Yvonne J K, Beecham, Gary W, Martin, Eden R, Pericak-Vance, Margaret A, Zuchner, Stephan, Vance, Jeffery M, Gilbert, John R

Volltext

Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma von Venkatesan, Arvind M, Vyas, Rajesh, Gramann, Alec K, Dresser, Karen, Gujja, Sharvari, Bhatnagar, Sanchita, Chhangawala, Sagar, Gomes, Camilla Borges Ferreira, Xi, Hualin Simon, Lian, Christine G, Houvras, Yariv, Edwards, Yvonne J K, Deng, April, Green, Michael, Ceol, Craig J

Volltext

Human transcription factors responsive to initial reprogramming predominantly undergo legitimate reprogramming during fibroblast conversion to iPSCs von Cevallos, Ricardo R., Edwards, Yvonne J. K., Parant, John M., Yoder, Bradley K., Hu, Kejin

Volltext

Exome sequencing allows for rapid gene identification in a Charcot-Marie-Tooth family von Montenegro, Gladys, Powell, Eric, Huang, Jia, Speziani, Fiorella, Edwards, Yvonne J.K., Beecham, Gary, Hulme, William, Siskind, Carly, Vance, Jeffery, Shy, Michael, Züchner, Stephan

Volltext

The cJUN NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution von Girnius, Nomeda, Edwards, Yvonne J. K., Davis, Roger J.

Volltext

Mutations in OTOGL, Encoding the Inner Ear Protein Otogelin-like, Cause Moderate Sensorineural Hearing Loss von YARIZ, Kemal O, DUMAN, Duygu, OOSTRIK, Jaap, DIAZ-HORTA, Oscar, YOUNG, Juan I, TOKGOZ-YILMAZ, Suna, KONUKSEVEN, Ozlem, SHAHIN, Hashem, HETTERSCHIJT, Lisette, KANAAN, Moien, OONK, Anne M. M, EDWARDS, Yvonne J. K, CELIA ZAZO SECO, HUAWEI LI, ATALAY, Semra, BLANTON, Susan, DESMIDT, Alexandra A, LIU, Xue-Zhong, PENNINGS, Ronald J. E, ZHONGMIN LU, CHEN, Zheng-Yi, KREMER, Hannie, TEKIN, Mustafa, DALLMAN, Julia, MINGQIAN HUANG, PETERS, TheoA, SIRMACI, Asli, NA LU, SCHRADERS, Margit, SKROMNE, Isaac

Volltext

Gld2-catalyzed 3' monoadenylation of miRNAs in the hippocampus has no detectable effect on their stability or on animal behavior von Mansur, Fernanda, Ivshina, Maria, Gu, Weifeng, Schaevitz, Laura, Stackpole, Emily, Gujja, Sharvari, Edwards, Yvonne J K, Richter, Joel D

Volltext

Changes in the Transcriptome and Chromatin Landscape in BRAFi-Resistant Melanoma Cells von Reddi, Kiran Kumar, Guruvaiah, Praveen, Edwards, Yvonne J K, Gupta, Romi

Volltext

Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes von Aparicio, Samuel, Chapman, Jarrod, Stupka, Elia, Putnam, Nik, Chia, Jer-ming, Dehal, Paramvir, Christoffels, Alan, Rash, Sam, Hoon, Shawn, Smit, Arian, Maarten D. Sollewijn Gelpke, Roach, Jared, Oh, Tania, Ho, Isaac Y., Wong, Marie, Detter, Chris, Verhoef, Frans, Predki, Paul, Tay, Alice, Lucas, Susan, Richardson, Paul, Smith, Sarah F., Clark, Melody S., Yvonne J. K. Edwards, Doggett, Norman, Zharkikh, Andrey, Tavtigian, Sean V., Pruss, Dmitry, Barnstead, Mary, Evans, Cheryl, Baden, Holly, Powell, Justin, Glusman, Gustavo, Rowen, Lee, Hood, Leroy, Tan, Y. H., Elgar, Greg, Hawkins, Trevor, Venkatesh, Byrappa, Rokhsar, Daniel, Brenner, Sydney

Volltext

Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation von Smulan, Lorissa J., Ding, Wei, Freinkman, Elizaveta, Gujja, Sharvari, Edwards, Yvonne J.K., Walker, Amy K.

Volltext