HDAC Inhibitors in Acute Myeloid Leukemia von San José-Enériz, Edurne, Gimenez-Camino, Naroa, Agirre, Xabier, Prosper, Felipe

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A network-based approach to integrate nutrient microenvironment in the prediction of synthetic lethality in cancer metabolism von Apaolaza, Iñigo, San José-Enériz, Edurne, Valcarcel, Luis V, Agirre, Xabier, Prosper, Felipe, Planes, Francisco J

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Epigenetic Silencing of the Tumor Suppressor MicroRNA Hsa-miR-124a Regulates CDK6 Expression and Confers a Poor Prognosis in Acute Lymphoblastic Leukemia von AGIRRE, Xabier, VILAS-ZORNOZA, Amaia, RIFON, José, BANDRES, Eva, CALASANZ, Maria José, MARTIN, Vanesa, HEINIGER, Anabel, TORRES, Antonio, SIEBERT, Reiner, ROMAN-GOMEZ, José, PROSPER, Felipe, JIMENEZ-VELASCO, Antonio, IGNACIO MARTIN-SUBERO, José, CORDEU, Lucia, GARATE, Leire, SAN JOSE-ENERIZ, Edurne, ABIZANDA, Gloria, RODRIGUEZ-OTERO, Paula, FORTES, Puri

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Identifying Lethal Dependencies with HUGE Predictive Power von Gimeno, Marian, San José-Enériz, Edurne, Rubio, Angel, Garate, Leire, Miranda, Estíbaliz, Castilla, Carlos, Agirre, Xabier, Prosper, Felipe, Carazo, Fernando

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Epigenetic Regulation of MicroRNAs in Acute Lymphoblastic Leukemia von ROMAN-GOMEZ, Jose, AGIRRE, Xabier, MARTIN, Vanesa, CASTILLEJO, Juan Antonio, BANDRES, Eva, CALASANZ, Maria José, SIEBERT, Reiner, HEINIGER, Anabel, TORRES, Antonio, PROSPER, Felipe, JIMENEZ-VELASCO, Antonio, ARQUEROS, Victor, VILAS-ZORNOZA, Amaia, RODRIGUEZ-OTERO, Paula, MARTIN-SUBERO, Inaki, GARATE, Leire, CORDEU, Lucia, SAN JOSE-ENERIZ, Edurne

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Characterization of the paracrine effects of human skeletal myoblasts transplanted in infarcted myocardium von Perez-Ilzarbe, Maitane, Agbulut, Onnik, Pelacho, Beatriz, Ciorba, Cristina, Jose-Eneriz, Edurne San, Desnos, Michel, Hagège, Albert A., Aranda, Pablo, Andreu, Enrique J., Menasché, Philippe, Prósper, Felipe

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Dual Targeting of Histone Methyltransferase G9a and DNA‐Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma von Bárcena‐Varela, Marina, Caruso, Stefano, Llerena, Susana, Álvarez‐Sola, Gloria, Uriarte, Iker, Latasa, M. Ujue, Urtasun, Raquel, Rebouissou, Sandra, Alvarez, Laura, Jimenez, Maddalen, Santamaría, Eva, Rodriguez‐Ortigosa, Carlos, Mazza, Giuseppe, Rombouts, Krista, San José‐Eneriz, Edurne, Rabal, Obdulia, Agirre, Xabier, Iraburu, Maria, Santos‐Laso, Alvaro, Banales, Jesus M., Zucman‐Rossi, Jessica, Prósper, Felipe, Oyarzabal, Julen, Berasain, Carmen, Ávila, Matías A., Fernández‐Barrena, Maite G.

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Epigenetic regulation of the non‐canonical Wnt pathway in acute myeloid leukemia von Martín, Vanesa, Valencia, Ana, Agirre, Xabier, Cervera, Jose, Jose‐Eneriz, Edurne San, Vilas‐Zornoza, Amaia, Rodriguez‐Otero, Paula, Sanz, Miguel A., Herrera, Concepción, Torres, Antonio, Prosper, Felipe, Román‐Gómez, Jose

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Explainable artificial intelligence for precision medicine in acute myeloid leukemia von Gimeno, Marian, San José-Enériz, Edurne, Villar, Sara, Agirre, Xabier, Prosper, Felipe, Rubio, Angel, Carazo, Fernando

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Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease von Garcia-Gomez, Antonio, Li, Tianlu, de la Calle-Fabregat, Carlos, Rodríguez-Ubreva, Javier, Ciudad, Laura, Català-Moll, Francesc, Godoy-Tena, Gerard, Martín-Sánchez, Montserrat, San-Segundo, Laura, Muntión, Sandra, Morales, Xabier, Ortiz-de-Solórzano, Carlos, Oyarzabal, Julen, San José-Enériz, Edurne, Esteller, Manel, Agirre, Xabier, Prosper, Felipe, Garayoa, Mercedes, Ballestar, Esteban

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Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers von Agirre, Xabier, Castellano, Giancarlo, Pascual, Marien, Heath, Simon, Kulis, Marta, Segura, Victor, Bergmann, Anke, Esteve, Anna, Merkel, Angelika, Raineri, Emanuele, Agueda, Lidia, Blanc, Julie, Richardson, David, Clarke, Laura, Datta, Avik, Russiñol, Nuria, Queirós, Ana C, Beekman, Renée, Rodríguez-Madoz, Juan R, San José-Enériz, Edurne, Fang, Fang, Gutiérrez, Norma C, García-Verdugo, José M, Robson, Michael I, Schirmer, Eric C, Guruceaga, Elisabeth, Martens, Joost H A, Gut, Marta, Calasanz, Maria J, Flicek, Paul, Siebert, Reiner, Campo, Elías, Miguel, Jesús F San, Melnick, Ari, Stunnenberg, Hendrik G, Gut, Ivo G, Prosper, Felipe, Martín-Subero, José I

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Methylation status of Wnt signaling pathway genes affects the clinical outcome of Philadelphia‐positive acute lymphoblastic leukemia von Martin, Vanesa, Agirre, Xabier, Jiménez‐Velasco, Antonio, José‐Eneriz, Edurne San, Cordeu, Lucia, Gárate, Leire, Vilas‐Zornoza, Amaia, Castillejo, Juan A., Heiniger, Anabel, Prósper, Felipe, Torres, Antonio, Roman‐Gomez, Jose

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BCR‐ABL1‐induced expression of HSPA8 promotes cell survival in chronic myeloid leukaemia von José‐Enériz, Edurne San, Román‐Gómez, José, Cordeu, Lucia, Ballestar, Esteban, Gárate, Leire, Andreu, Enrique J., Isidro, Isabel, Guruceaga, Elizabeth, Jiménez‐Velasco, Antonio, Heiniger, Anabel, Torres, Antonio, Calasanz, Maria José, Esteller, Manel, Gutiérrez, Norma C., Rubio, Angel, Pérez‐Roger, Ignacio, Agirre, Xabier, Prósper, Felipe

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Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome von Rodriguez-Madoz, Juan Roberto, San Jose-Eneriz, Edurne, Rabal, Obdulia, Zapata-Linares, Natalia, Miranda, Estibaliz, Rodriguez, Saray, Porciuncula, Angelo, Vilas-Zornoza, Amaia, Garate, Leire, Segura, Victor, Guruceaga, Elizabeth, Agirre, Xabier, Oyarzabal, Julen, Prosper, Felipe

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Modulation of tumor microenvironment by targeting histone acetylation in bladder cancer von Nunes, Sandra P., Morales, Lucia, Rubio, Carolina, Munera-Maravilla, Ester, Lodewijk, Iris, Suárez-Cabrera, Cristian, Martínez, Victor G., Pérez-Escavy, Mercedes, Pérez-Crespo, Miriam, Alonso Sánchez, Miguel, Montesinos, Esther, San José-Enériz, Edurne, Agirre, Xabier, Prósper, Felipe, Pineda-Lucena, Antonio, Henrique, Rui, Dueñas, Marta, Correia, Margareta P., Jerónimo, Carmen, Paramio, Jesús M.

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Down-regulated expression of hsa-miR-181c in Fanconi anemia patients: implications in TNFα regulation and proliferation of hematopoietic progenitor cells von Río, Paula, Agirre, Xabier, Garate, Leire, Baños, Rocío, Álvarez, Lara, San José-Enériz, Edurne, Badell, Isabel, Casado, José A., Garín, Marina, Prósper, Felipe, Bueren, Juan A.

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Downregulation of DBC1 expression in acute lymphoblastic leukaemia is mediated by aberrant methylation of its promoter von San José‐Enériz, Edurne, Agirre, Xabier, Román‐Gómez, José, Cordeu, Lucia, Garate, Leire, Jiménez‐Velasco, Antonio, Vázquez, Iria, Calasanz, María José, Heiniger, Anabel, Torres, Antonio, Prósper, Felipe

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Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression von Segovia, Cristina, San José-Enériz, Edurne, Munera-Maravilla, Ester, Martínez-Fernández, Mónica, Garate, Leire, Miranda, Estíbaliz, Vilas-Zornoza, Amaia, Lodewijk, Iris, Rubio, Carolina, Segrelles, Carmen, Valcárcel, Luis Vitores, Rabal, Obdulia, Casares, Noelia, Bernardini, Alejandra, Suarez-Cabrera, Cristian, López-Calderón, Fernando F., Fortes, Puri, Casado, José A., Dueñas, Marta, Villacampa, Felipe, Lasarte, Juan José, Guerrero-Ramos, Félix, de Velasco, Guillermo, Oyarzabal, Julen, Castellano, Daniel, Agirre, Xabier, Prósper, Felipe, Paramio, Jesús M.

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia von Román-Gómez, José, Cordeu, Lucia, Agirre, Xabier, Jiménez-Velasco, Antonio, San José-Eneriz, Edurne, Garate, Leire, Calasanz, María José, Heiniger, Anabel, Torres, Antonio, Prosper, Felipe

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Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies von San José-Enériz, Edurne, Agirre, Xabier, Rabal, Obdulia, Vilas-Zornoza, Amaia, Sanchez-Arias, Juan A., Miranda, Estibaliz, Ugarte, Ana, Roa, Sergio, Paiva, Bruno, Estella-Hermoso de Mendoza, Ander, Alvarez, Rosa María, Casares, Noelia, Segura, Victor, Martín-Subero, José I., Ogi, François-Xavier, Soule, Pierre, Santiveri, Clara M., Campos-Olivas, Ramón, Castellano, Giancarlo, de Barrena, Maite Garcia Fernandez, Rodriguez-Madoz, Juan Roberto, García-Barchino, Maria José, Lasarte, Juan Jose, Avila, Matias A, Martinez-Climent, Jose Angel, Oyarzabal, Julen, Prosper, Felipe

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