NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice von Zhang, Hongbo, Ryu, Dongryeol, Wu, Yibo, Gariani, Karim, Wang, Xu, Luan, Peiling, D'Amico, Davide, Ropelle, Eduardo R., Lutolf, Matthias P., Aebersold, Ruedi, Schoonjans, Kristina, Menzies, Keir J., Auwerx, Johan

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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice von Gariani, Karim, Menzies, Keir J., Ryu, Dongryeol, Wegner, Casey J., Wang, Xu, Ropelle, Eduardo R., Moullan, Norman, Zhang, Hongbo, Perino, Alessia, Lemos, Vera, Kim, Bohkyung, Park, Young‐Ki, Piersigilli, Alessandra, Pham, Tho X., Yang, Yue, Ku, Chai Siah, Koo, Sung I., Fomitchova, Anna, Cantó, Carlos, Schoonjans, Kristina, Sauve, Anthony A., Lee, Ji‐Young, Auwerx, Johan

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Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity von Cintra, Dennys E, Ropelle, Eduardo R, Moraes, Juliana C, Pauli, José R, Morari, Joseane, Souza, Claudio T de, Grimaldi, Renato, Stahl, Marcela, Carvalheira, José B, Saad, Mario J, Velloso, Licio A

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The proinflammatory effects of chronic excessive exercise von da Rocha, Alisson L., Pinto, Ana P., Kohama, Eike B., Pauli, José R., de Moura, Leandro P., Cintra, Dennys E., Ropelle, Eduardo R., da Silva, Adelino S.R.

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Metformin Amplifies Chemotherapy-Induced AMPK Activation and Antitumoral Growth von ROCHA, Guilherme Z, DIAS, Marília M, ROPELLE, Eduardo R, OSORIO-COSTA, Felipe, ROSSATO, Franco A, VERCESI, Anibal E, SAAD, Mario J. A, CARVALHEIRA, José B. C

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The dual and emerging role of physical exercise‐induced TFEB activation in the protection against Alzheimer's disease von Morais, Gustavo Paroschi, Sousa Neto, Ivo Vieira, Marafon, Bruno Brieda, Ropelle, Eduardo R., Cintra, Dennys E., Pauli, José R., Silva, Adelino S. R. da

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Gut microbiota is a key modulator of insulin resistance in TLR 2 knockout mice von Caricilli, Andréa M, Picardi, Paty K, de Abreu, Lélia L, Ueno, Mirian, Prada, Patrícia O, Ropelle, Eduardo R, Hirabara, Sandro Massao, Castoldi, Ângela, Vieira, Pedro, Camara, Niels O S, Curi, Rui, Carvalheira, José B, Saad, Mário J A

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Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans von van de Weijer, Tineke, Phielix, Esther, Bilet, Lena, Williams, Evan G, Ropelle, Eduardo R, Bierwagen, Alessandra, Livingstone, Roshan, Nowotny, Peter, Sparks, Lauren M, Paglialunga, Sabina, Szendroedi, Julia, Havekes, Bas, Moullan, Norman, Pirinen, Eija, Hwang, Jong-Hee, Schrauwen-Hinderling, Vera B, Hesselink, Matthijs K C, Auwerx, Johan, Roden, Michael, Schrauwen, Patrick

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Exercise alters the circadian rhythm of REV-ERB-α and downregulates autophagy-related genes in peripheral and central tissues von da Rocha, Alisson L., Pinto, Ana P., Bedo, Bruno L. S., Morais, Gustavo P., Oliveira, Luciana C., Carolino, Ruither O. G., Pauli, Jose R., Simabuco, Fernando M., de Moura, Leandro P., Ropelle, Eduardo R., Cintra, Dennys E., Rivas, Donato A., da Silva, Adelino S. R.

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Exercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice von Braga, Renata R., Crisol, Barbara M., Brícola, Rafael S., Sant’ana, Marcella R., Nakandakari, Susana C. B. R., Costa, Suleyma O., Prada, Patrícia O., da Silva, Adelino S. R., Moura, Leandro P., Pauli, José R., Cintra, Dennys E., Ropelle, Eduardo R.

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Impact of Different Physical Exercises on the Expression of Autophagy Markers in Mice von Pinto, Ana P., da Rocha, Alisson L., Marafon, Bruno B., Rovina, Rafael L., Munoz, Vitor R., da Silva, Lilian E. C. M., Pauli, Jose R., de Moura, Leandro P., Cintra, Dennys E., Ropelle, Eduardo R., da Silva, Adelino S. R.

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Physical Exercise Reduces Circulating Lipopolysaccharide and TLR4 Activation and Improves Insulin Signaling in Tissues of DIO Rats von OLIVEIRA, Alexandre G, CARVALHO, Bruno M, TOBAR, Natália, ROPELLE, Eduardo R, PAULI, José R, BAGAROLLI, Renata A, GUADAGNINI, Dioze, CARVALHEIRA, José B. C, SAAD, Mario J. A

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Excessive training induces molecular signs of pathologic cardiac hypertrophy von da Rocha, Alisson L., Teixeira, Giovana R., Pinto, Ana P., Morais, Gustavo P., Oliveira, Luciana da C., de Vicente, Larissa Gaioto, da Silva, Lilian E. C. M., Pauli, José R., Cintra, Dennys E., Ropelle, Eduardo R., de Moura, Leandro P., Mekary, Rania A., de Freitas, Ellen C., da Silva, Adelino S. R.

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Downhill Running-Based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway without Concomitant Decrease of Inflammatory Proteins von da Rocha, Alisson L, Pereira, Bruno C, Pauli, José R, Cintra, Dennys E, de Souza, Claudio T, Ropelle, Eduardo R, da Silva, Adelino S R

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Exercise Counterbalances Rho/ROCK2 Signaling Impairment in the Skeletal Muscle and Ameliorates Insulin Sensitivity in Obese Mice von Munoz, Vitor R., Gaspar, Rafael C., Severino, Matheus B., Macedo, Ana P. A., Simabuco, Fernando M., Ropelle, Eduardo R., Cintra, Dennys E., da Silva, Adelino S. R., Kim, Young-Bum, Pauli, Jose Rodrigo

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Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues von da Rocha, Alisson L., Pinto, Ana P., Morais, Gustavo P., Marafon, Bruno B., Rovina, Rafael L., Veras, Allice S. C., Teixeira, Giovana R., Pauli, Jose R., de Moura, Leandro P., Cintra, Dennys E., Ropelle, Eduardo R., Rivas, Donato A., da Silva, Adelino S. R.

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Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts von de Vicente, Larissa G., Pinto, Ana P., Muñoz, Vitor R., Rovina, Rafael L., da Rocha, Alisson L., Gaspar, Rafael C., da Silva, Lilian E.C.M., Simabuco, Fernando M., Frantz, Fabiani G., Pauli, José R., de Moura, Leandro P., Cintra, Dennys E., Ropelle, Eduardo R., da Silva, Adelino S.R.

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IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exercise von Pinto, Ana P., Muñoz, Vitor R., da Rocha, Alisson L., Rovina, Rafael L., Ferrari, Gustavo D., Alberici, Luciane C., Simabuco, Fernando M., Teixeira, Giovana R., Pauli, José R., de Moura, Leandro P., Cintra, Dennys E., Ropelle, Eduardo R., Freitas, Ellen C., Rivas, Donato A., da Silva, Adelino S. R.

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Hypothalamic S1P/S1PR1 axis controls energy homeostasis von Silva, Vagner R. R., Micheletti, Thayana O., Pimentel, Gustavo D., Katashima, Carlos K., Lenhare, Luciene, Morari, Joseane, Mendes, Maria Carolina S., Razolli, Daniela S., Rocha, Guilherme Z., de Souza, Claudio T., Ryu, Dongryeol, Prada, Patrícia O., Velloso, Lício A., Carvalheira, José B. C., Rodrigo Pauli, José, Cintra, Dennys E., Ropelle, Eduardo R.

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Exercise decreases CLK2 in the liver of obese mice and prevents hepatic fat accumulation von Muñoz, Vitor R., Gaspar, Rafael C., Kuga, Gabriel K., Nakandakari, Susana C. B. R., Baptista, Igor L., Mekary, Rania A., da Silva, Adelino S. R., de Moura, Leandro P., Ropelle, Eduardo R., Cintra, Dennys E., Pauli, José R.

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