Insights on variant analysis in silico tools for pathogenicity prediction von Garcia, Felipe Antonio de Oliveira, de Andrade, Edilene Santos, Palmero, Edenir Inez

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Unveiling the role of MGMT and DAPK hypermethylation in response to anti‐EGFR agents: Molecular insights for advancing HNSCC treatment von Arantes, Lidia Maria Rebolho Batista, Silva‐Oliveira, Renato José, Carvalho, Ana Carolina, Melendez, Matias Eliseo, Sorroche, Bruna Pereira, Jesus Teixeira, Renan, Tostes, Katiane, Palmero, Edenir Inez, Reis, Rui Manuel, Carvalho, André Lopes

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New insights on familial colorectal cancer type X syndrome von Garcia, Felipe Antonio de Oliveira, de Andrade, Edilene Santos, de Campos Reis Galvão, Henrique, da Silva Sábato, Cristina, Campacci, Natália, de Paula, Andre Escremin, Evangelista, Adriane Feijó, Santana, Iara Viana Vidigal, Melendez, Matias Eliseo, Reis, Rui Manuel, Palmero, Edenir Inez

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The history of families at-risk for hereditary breast and ovarian cancer: what are the impacts of genetic counseling and testing? von Campacci, Natalia, Grasel, Rebeca Silveira, Galvão, Henrique de Campos Reis, Garcia, Lucas França, Ribeiro, Paula Carvalho, Pereira, Kercy Fram de Jesus de Sena, Goldim, José Roberto, Ashton-Prolla, Patricia, Palmero, Edenir Inêz

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Hereditary Breast Cancer in the Brazilian State of Ceará (The CHANCE Cohort): Higher-Than-Expected Prevalence of Recurrent Germline Pathogenic Variants von Gifoni, Ana Carolina Leite Vieira Costa, Gifoni, Markus Andret Cavalcante, Wotroba, Camila Martins, Palmero, Edenir Inez, Costa, Eduardo Leite Vieira, dos Santos, Wellington, Achatz, Maria Isabel

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Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population von da Costa E Silva Carvalho, Simone, Cury, Nathalia Moreno, Brotto, Danielle Barbosa, de Araujo, Luiza Ferreira, Rosa, Reginaldo Cruz Alves, Texeira, Lorena Alves, Plaça, Jessica Rodrigues, Marques, Adriana Aparecida, Peronni, Kamila Chagas, Ruy, Patricia de Cássia, Molfetta, Greice Andreotti, Moriguti, Julio Cesar, Carraro, Dirce Maria, Palmero, Edenir Inêz, Ashton-Prolla, Patricia, de Faria Ferraz, Victor Evangelista, Silva, Jr, Wilson Araujo

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Whole-Exome Sequencing Identifies Pathogenic Germline Variants in Patients with Lynch-Like Syndrome von dos Santos, Wellington, de Andrade, Edilene Santos, Garcia, Felipe Antonio de Oliveira, Campacci, Natália, Sábato, Cristina da Silva, Melendez, Matias Eliseo, Reis, Rui Manuel, Galvão, Henrique de Campos Reis, Palmero, Edenir Inez

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A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America von Rossi, Benedito Mauro, Palmero, Edenir Inêz, López-Kostner, Francisco, Sarroca, Carlos, Vaccaro, Carlos Alberto, Spirandelli, Florencia, Ashton-Prolla, Patricia, Rodriguez, Yenni, de Campos Reis Galvão, Henrique, Reis, Rui Manuel, Escremim de Paula, André, Capochin Romagnolo, Luis Gustavo, Alvarez, Karin, Della Valle, Adriana, Neffa, Florencia, Kalfayan, Pablo German, Spirandelli, Enrique, Chialina, Sergio, Gutiérrez Angulo, Melva, Castro-Mujica, Maria Del Carmen, Sanchez de Monte, Julio, Quispe, Richard, da Silva, Sabrina Daniela, Rossi, Norma Teresa, Barletta-Carrillo, Claudia, Revollo, Susana, Taborga, Ximena, Morillas, L Lena, Tubeuf, Hélène, Monteiro-Santos, Erika Maria, Piñero, Tamara Alejandra, Dominguez-Barrera, Constantino, Wernhoff, Patrik, Martins, Alexandra, Hovig, Eivind, Møller, Pål, Dominguez-Valentin, Mev

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Cost-Effectiveness of BRCA 1/2 Genetic Test and Preventive Strategies: Using Real-World Data From an Upper-Middle Income Country von Lourenção, Marina, Simões Correa Galendi, Julia, Galvão, Henrique de Campos Reis, Antoniazzi, Augusto Perazzolo, Grasel, Rebeca Silveira, Carvalho, André Lopes, Mauad, Edmundo Carvalho, de Oliveira, Jorge Henrique Caldeira, Reis, Rui Manuel, Mandrik, Olena, Palmero, Edenir Inêz

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TP53 variants of uncertain significance: increasing challenges in variant interpretation and genetic counseling von Bittar, Camila Matzenbacher, Vieira, Igor Araujo, Sabato, Cristina Silva, Andreis, Tiago Finger, Alemar, Bárbara, Artigalás, Osvaldo, Galvão, Henrique de Campos Reis, Macedo, Gabriel S., Palmero, Edenir Inez, Ashton-Prolla, Patricia

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Evaluation of MLH1 variants of unclear significance von Köger, Nicole, Paulsen, Lea, López-Kostner, Francisco, Della Valle, Adriana, Vaccaro, Carlos Alberto, Palmero, Edenir Inêz, Alvarez, Karin, Sarroca, Carlos, Neffa, Florencia, Kalfayan, Pablo German, Gonzalez, Maria Laura, Rossi, Benedito Mauro, Reis, R. M., Brieger, Angela, Zeuzem, Stefan, Hinrichsen, Inga, Dominguez-Valentin, Mev, Plotz, Guido

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miRNA expression profiling of hereditary breast tumors from BRCA1- and BRCA2-germline mutation carriers in Brazil von Pessôa-Pereira, Danielle, Evangelista, Adriane Feijó, Causin, Rhafaela Lima, da Costa Vieira, René Aloisio, Abrahão-Machado, Lucas Faria, Santana, Iara Viana Vidigal, da Silva, Vinicius Duval, de Souza, Karen Cristina Borba, de Oliveira-Silva, Renato José, Fernandes, Gabriela Carvalho, Reis, Rui Manuel, Palmero, Edenir Inêz, Marques, Márcia Maria Chiquitelli

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Clinical and Molecular Assessment of Patients with Lynch Syndrome and Sarcomas Underpinning the Association with MSH2 Germline Pathogenic Variants von de Angelis de Carvalho, Nathália, Niitsuma, Bianca Naomi, Kozak, Vanessa Nascimento, Costa, Felipe D’almeida, de Macedo, Mariana Petaccia, Kupper, Bruna Elisa Catin, Silva, Maria Letícia Gobo, Formiga, Maria Nirvana, Volc, Sahlua Miguel, Aguiar Junior, Samuel, Palmero, Edenir Inez, Casali-da-Rocha, José Cláudio, Carraro, Dirce Maria, Torrezan, Giovana Tardin

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Clinical and Molecular Characterization of Surgically Treated Oropharynx Squamous Cell Carcinoma Samples von de Carvalho, Ana Carolina, Melendez, Matias Eliseo, da Silva Sabato, Cristina, Palmero, Edenir Inez, Arantes, Lidia Maria Rebolho Batista, Neto, Cristovam Scapulatempo, Carvalho, André Lopes

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Exploring the frequency of a TP53 polyadenylation signal variant in tumor DNA from patients diagnosed with lung adenocarcinomas, sarcomas and uterine leiomyomas von Vieira, Igor Araujo, Viola, Guilherme Danielski, Pezzi, Eduarda Heidrich, Kowalski, Thayne Woycinck, Fernandes, Bruna Vieira, Andreis, Tiago Finger, Bom, Natascha, Sonnenstrahl, Giulianna, Rocha, Yasminne Marinho de Araújo, Corrêa, Bruno da Silveira, Donatti, Luiza Mezzomo, Sant'Anna, Gabriela Dos Santos, Corleta, Helena von Eye, Brum, Ilma Simoni, Rosset, Clévia, Vianna, Fernanda Sales Luiz, Macedo, Gabriel S, Palmero, Edenir Inez, Ashton-Prolla, Patricia

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Cancer-related worry and risk perception in Brazilian individuals seeking genetic counseling for hereditary breast cancer von Palmero, Edenir Inêz, Campacci, Natalia, Schüler-Faccini, Lavinia, Giugliani, Roberto, Rocha, José Claudio Casali da, Vargas, Fernando Regla, Ashton-Prolla, Patricia

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Using Co-segregation and Loss of Heterozygosity Analysis to Define the Pathogenicity of Unclassified Variants in Hereditary Breast Cancer Patients von Grasel, Rebeca Silveira, Felicio, Paula Silva, de Paula, André Escremim, Campacci, Natalia, Garcia, Felipe Antônio de Oliveira, de Andrade, Edilene Santos, Evangelista, Adriane Feijó, Fernandes, Gabriela Carvalho, Sabato, Cristina da Silva, De Marchi, Pedro, Souza, Cristiano de Pádua, de Paula, Cláudia Alessandra Andrade, Torrezan, Giovana Tardin, Galvão, Henrique de Campos Reis, Carraro, Dirce Maria, Palmero, Edenir Inêz

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p53 signaling pathway polymorphisms, cancer risk and tumor phenotype in TP53 R337H mutation carriers von Macedo, Gabriel S., Vieira, Igor Araujo, Vianna, Fernanda Salles Luiz, Alemar, Barbara, Giacomazzi, Juliana, Brandalize, Ana Paula Carneiro, Caleffi, Maira, Volc, Sahlua Miguel, de Campos Reis Galvão, Henrique, Palmero, Edenir Inez, Achatz, Maria Isabel, Ashton-Prolla, Patricia

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Detection of R337H, a germline TP53 mutation predisposing to multiple cancers, in asymptomatic women participating in a breast cancer screening program in Southern Brazil von Palmero, Edenir Inêz, Schüler-Faccini, Lavínia, Caleffi, Maira, Achatz, Maria Isabel Waddington, Olivier, Magali, Martel-Planche, Ghyslaine, Marcel, Virginie, Aguiar, Ernestina, Giacomazzi, Juliana, Ewald, Ingrid Petroni, Giugliani, Roberto, Hainaut, Pierre, Ashton-Prolla, Patricia

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Rare germline variant (rs78378222) in the TP53 3' UTR: Evidence for a new mechanism of cancer predisposition in Li-Fraumeni syndrome von Macedo, Gabriel S, Araujo Vieira, Igor, Brandalize, Ana Paula, Giacomazzi, Juliana, Inez Palmero, Edenir, Volc, Sahlua, Rodrigues Paixão-Côrtes, Vanessa, Caleffi, Maira, Silva Alves, Michele, Achatz, Maria Isabel, Hainaut, Pierre, Ashton-Prolla, Patricia

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