Understanding of BRCA VUS genetic results by breast cancer specialists von Eccles, B K, Copson, E, Maishman, T, Abraham, J E, Eccles, D M

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Structural and functional features of central nervous system lymphatic vessels von Louveau, Antoine, Smirnov, Igor, Keyes, Timothy J., Eccles, Jacob D., Rouhani, Sherin J., Peske, J. David, Derecki, Noel C., Castle, David, Mandell, James W., Lee, Kevin S., Harris, Tajie H., Kipnis, Jonathan

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BRCA1 and BRCA2 genetic testing—pitfalls and recommendations for managing variants of uncertain clinical significance von Eccles, D.M., Mitchell, G., Monteiro, A.N.A., Schmutzler, R., Couch, F.J., Spurdle, A.B., Gómez-García, E.B., Driessen, R., Lindor, N.M., Blok, M.J., Moller, P., de la Hoya, M., Pal, T., Domchek, S., Nathanson, K., Van Asperen, C., Diez, O., Rheim, K., Stoppa-Lyonnet, D., Parsons, M., Goldgar, D.

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Ion torrent high throughput mitochondrial genome sequencing (HTMGS) von Harvey, N R, Albury, C L, Stuart, S, Benton, M C, Eccles, D A, Connell, J R, Sutherland, H G, Allcock, R J N, Lea, R A, Haupt, L M, Griffiths, L R

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Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies von Antoniou, A., Pharoah, P.D.P., Narod, S., Risch, H.A., Eyfjord, J.E., Hopper, J.L., Loman, N., Olsson, H., Johannsson, O., Borg, Å., Pasini, B., Radice, P., Manoukian, S., Eccles, D.M., Tang, N., Olah, E., Anton-Culver, H., Warner, E., Lubinski, J., Gronwald, J., Gorski, B., Tulinius, H., Thorlacius, S., Eerola, H., Nevanlinna, H., Syrjäkoski, K., Kallioniemi, O.-P., Thompson, D., Evans, C., Peto, J., Lalloo, F., Evans, D.G., Easton, D.F.

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Obesity and the outcome of young breast cancer patients in the UK: the POSH study von Copson, E.R., Cutress, R.I., Maishman, T., Eccles, B.K., Gerty, S., Stanton, L., Altman, D.G., Durcan, L., Wong, C., Simmonds, P.D., Jones, L., Eccles, D.M.

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A novel HER2-positive breast cancer phenotype arising from germline TP53 mutations von Wilson, J R F, Bateman, A C, Hanson, H, An, Q, Evans, G, Rahman, N, Jones, J L, Eccles, D M

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Clinical Impact of Constitutional Genomic Testing on Current Breast Cancer Care von Cheah, W., Cutress, R.I., Eccles, D., Copson, E.

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Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer von Evans, D G, Howell, A, Ward, D, Lalloo, F, Jones, J L, Eccles, D M

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Tamoxifen metabolism predicts drug concentrations and outcome in premenopausal patients with early breast cancer von Saladores, P, Mürdter, T, Eccles, D, Chowbay, B, Zgheib, N K, Winter, S, Ganchev, B, Eccles, B, Gerty, S, Tfayli, A, Lim, J S L, Yap, Y S, Ng, R C H, Wong, N S, Dent, R, Habbal, M Z, Schaeffeler, E, Eichelbaum, M, Schroth, W, Schwab, M, Brauch, H

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Spatiotemporal Relationships between Two Closely‐spaced Strombolian‐style Vents, Yasur, Vanuatu von Simons, B.C., Jolly, A.D., Eccles, J.D., Cronin, S.J.

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A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO von Evans, D G R, Eccles, D M, Rahman, N, Young, K, Bulman, M, Amir, E, Shenton, A, Howell, A, Lalloo, F

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Family history and outcome of young patients with breast cancer in the UK (POSH study) von Eccles, B. K., Copson, E. R., Cutress, R. I., Maishman, T., Altman, D. G., Simmonds, P., Gerty, S. M., Durcan, L., Stanton, L., Eccles, D. M.

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Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes von Cubuk, C., Garrett, A., Choi, S., King, L., Loveday, C., Torr, B., Burghel, G. J., Durkie, M., Callaway, A., Robinson, R., Drummond, J., Berry, I., Wallace, A., Eccles, D., Tischkowitz, M., Whiffin, N., Ware, J. S., Hanson, H., Turnbull, C., CanVIG-UK

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Machine learning approaches for the discovery of gene-gene interactions in disease data von Upstill-Goddard, Rosanna, Eccles, Diana, Fliege, Joerg, Collins, Andrew

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An evaluation of the prognostic model PREDICT using the POSH cohort of women aged ⩽40 years at breast cancer diagnosis von Maishman, T, Copson, E, Stanton, L, Gerty, S, Dicks, E, Durcan, L, Wishart, G C, Pharoah, P, Eccles, D

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Dosage analysis of cancer predisposition genes by multiplex ligation-dependent probe amplification von BUNYAN, D. J, ECCLES, D. M, CROSS, N. C. P, SILLIBOURNE, J, WILKINS, E, THOMAS, N. Simon, SHEA-SIMONDS, J, DUNCAN, P. J, CURTIS, C. E, ROBINSON, D. O, HARVEY, J. F

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Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics von Antoniou, A C, Hardy, R, Walker, L, Evans, D G, Shenton, A, Eeles, R, Shanley, S, Pichert, G, Izatt, L, Rose, S, Douglas, F, Eccles, D, Morrison, P J, Scott, J, Zimmern, R L, Easton, D F, Pharoah, P D P

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Breast and ovarian cancer risks to carriers of the BRCA1 5382insC and 185delAG and BRCA2 6174delT mutations: a combined analysis of 22 population based studies von Antoniou, A C, Pharoah, P D P, Narod, S, Risch, H A, Eyfjord, J E, Hopper, J L, Olsson, H, Johannsson, O, Borg, Å, Pasini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tulinius, H, Thorlacius, S, Eerola, H, Nevanlinna, H, Syrjäkoski, K, Kallioniemi, O-P, Thompson, D, Evans, C, Peto, J, Lalloo, F, Evans, D G, Easton, D F

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Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome von Burn, John, Bishop, D. Timothy, Mecklin, Jukka-Pekka, Macrae, Finlay, Möslein, Gabriela, Olschwang, Sylviane, Bisgaard, Marie-Luise, Ramesar, Raj, Eccles, Diana, Maher, Eamonn R, Bertario, Lucio, Jarvinen, Heikki J, Lindblom, Annika, Evans, D. Gareth, Lubinski, Jan, Morrison, Patrick J, Ho, Judy W.C, Vasen, Hans F.A, Side, Lucy, Thomas, Huw J.W, Scott, Rodney J, Dunlop, Malcolm, Barker, Gail, Elliott, Faye, Jass, Jeremy R, Fodde, Ricardo, Lynch, Henry T, Mathers, John C

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