IL-15 induces strong but short-lived tumor-infiltrating CD8 T cell responses through the regulation of Tim-3 in breast cancer von Heon, Elise K., Wulan, Hasi, Macdonald, Loch P., Malek, Adel O., Braunstein, Glenn H., Eaves, Connie G., Schattner, Mark D., Allen, Peter M., Alexander, Michael O., Hawkins, Cynthia A., McGovern, Dermot W., Freeman, Richard L., Amir, Eitan P., Huse, Jason D., Zaltzman, Jeffrey S., Kauff, Noah P., Meyers, Paul G., Gleason, Michelle H., Overholtzer, Michael G., Wiseman, Sam S., Streutker, Catherine D., Asa, Sylvia W., McAlindon, Timothy P., Newcomb, Polly O., Sorensen, Poul M., Press, Oliver A.

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Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth von He, Aina, Tian, Songhai, Kopper, Oded, Horan, Daniel J, Chen, Peng, Bronson, Roderick T, Sheng, Ren, Wu, Hao, Sui, Lufei, Zhou, Kun, Tao, Liang, Wu, Quan, Huang, Yujing, Shen, Zan, Han, Sen, Chen, Xueqing, Chen, Hong, He, Xi, Robling, Alexander G, Jin, Rongsheng, Clevers, Hans, Xiang, Dongxi, Li, Zhe, Dong, Min

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Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs von Benz, Claudia, Copley, Michael R., Kent, David G., Wohrer, Stefan, Cortes, Adrian, Aghaeepour, Nima, Ma, Elaine, Mader, Heidi, Rowe, Keegan, Day, Christopher, Treloar, David, Brinkman, Ryan R., Eaves, Connie J.

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The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells von Copley, Michael R., Babovic, Sonja, Benz, Claudia, Knapp, David J. H. F., Beer, Philip A., Kent, David G., Wohrer, Stefan, Treloar, David Q., Day, Christopher, Rowe, Keegan, Mader, Heidi, Kuchenbauer, Florian, Humphries, R. Keith, Eaves, Connie J.

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MicroRNA-150 expression induces myeloid differentiation of human acute leukemia cells and normal hematopoietic progenitors von Morris, Valerie A, Zhang, Ailin, Yang, Taimei, Stirewalt, Derek L, Ramamurthy, Ranjani, Meshinchi, Soheil, Oehler, Vivian G

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Impact of long-term exposure to the tyrosine kinase inhibitor imatinib on the skeleton of growing rats von Tauer, Josephine T, Hofbauer, Lorenz C, Jung, Roland, Gerdes, Sebastian, Glauche, Ingmar, Erben, Reinhold G, Suttorp, Meinolf

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High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays von Lecault, Véronique, VanInsberghe, Michael, Sekulovic, Sanja, Knapp, David J H F, Wohrer, Stefan, Bowden, William, Viel, Francis, McLaughlin, Thomas, Jarandehei, Asefeh, Miller, Michelle, Falconnet, Didier, White, Adam K, Kent, David G, Copley, Michael R, Taghipour, Fariborz, Eaves, Connie J, Humphries, R Keith, Piret, James M, Hansen, Carl L

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Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy von Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

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Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect von Bowie, Michelle B, McKnight, Kristen D, Kent, David G, McCaffrey, Lindsay, Hoodless, Pamela A, Eaves, Connie J

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin von Leong, Kevin G, Niessen, Kyle, Kulic, Iva, Raouf, Afshin, Eaves, Connie, Pollet, Ingrid, Karsan, Aly

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Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties von Bowie, Michelle B, Kent, David G, Dykstra, Brad, McKnight, Kristen D, McCaffrey, Lindsay, Hoodless, Pamela A, Eaves, Connie J

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Distinct Stromal Cell Factor Combinations Can Separately Control Hematopoietic Stem Cell Survival, Proliferation, and Self-Renewal von Wohrer, Stefan, Knapp, David J.H.F., Copley, Michael R., Benz, Claudia, Kent, David G., Rowe, Keegan, Babovic, Sonja, Mader, Heidi, Oostendorp, Robert A.J., Eaves, Connie J.

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Epigenetic and functional changes imposed by NUP98-HOXA9 in a genetically engineered model of chronic myeloid leukemia progression von Sloma, Ivan, Beer, Philip, Desterke, Christophe, Bulaeva, Elizabeth, Bilenky, Misha, Carles, Annaick, Moksa, Michelle, Raghuram, Kamini, Brimacombe, Cedric, Lambie, Karen, Turhan, Ali G., Wagner-Ballon, Orianne, Gaulard, Philippe, Humphries, Keith, Hirst, Martin, Eaves, Connie J.

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Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential von Kent, David G., Copley, Michael R., Benz, Claudia, Wöhrer, Stefan, Dykstra, Brad J., Ma, Elaine, Cheyne, John, Zhao, Yongjun, Bowie, Michelle B., Zhao, Yun, Gasparetto, Maura, Delaney, Allen, Smith, Clayton, Marra, Marco, Eaves, Connie J.

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Intermittent Exposure of Primitive Quiescent Chronic Myeloid Leukemia Cells to Granulocyte-Colony Stimulating Factor In vitro Promotes their Elimination by Imatinib Mesylate von JØRGENSEN, Heather G, COPLAND, Mhairi, ALLAN, Elaine K, XIAOYAN JIANG, EAVES, Allen, EAVES, Connie, HOLYOAKE, Tessa L

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Primitive quiescent leukemic cells from patients with chronic myeloid leukemia spontaneously initiate factor-independent growth in vitro in association with up-regulation of expres... von Holyoake, Tessa L., Jiang, Xiaoyan, Jorgensen, Heather G., Graham, Susan, Alcorn, Michael J., Laird, Chris, Eaves, Allen C., Eaves, Connie J.

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CXCR4-related increase of circulating human lymphoid progenitors after allogeneic hematopoietic stem cell transplantation von Glauzy, Salomé, André-Schmutz, Isabelle, Larghero, Jérôme, Ezine, Sophie, Peffault de Latour, Régis, Moins-Teisserenc, Hélène, Servais, Sophie, Robin, Marie, Socié, Gérard, Clave, Emmanuel, Toubert, Antoine

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Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells von Bowie, Michelle B., Kent, David G., Copley, Michael R., Eaves, Connie J.

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The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery von Adams, David, Altucci, Lucia, Amit, Ido, Aparicio, Samuel, Arima, Takahiro, Asnafi, Vahid, Bae, Jae-Bum, Bassler, Kevin, Bilenky, Mikhail, Boehm, Bernhard, Bourque, Guillaume, Brors, Benedikt, Bussemakers, Marion J., Chadwick, Lisa, Chen, Wei, Cheung, Tom H., Choi, Nak Hyen, Chung, Ho-Ryun, Clarke, Laura, Dermitzakis, Manolis, Dylag, Tomasz, Eaves, Connie J., Ebert, Peter, Eils, Jürgen, Enver, Tariq, Ferguson-Smith, Anne, Fitzgibbon, Jude, Flicek, Paul, Fraser, Peter, Gasparoni, Nina, Gasparoni, Gilles, Heath, Simon, Helin, Kristian, Hitz, Benjamin C., Horsthemke, Bernhard, Ip, Nancy Y., Ito, Takashi, Jenuwein, Thomas, Joly, Yann, Kanai, Yae, Kang, Hee Gyung, Kiemer, Alexandra K., Kim, Song Cheol, Kim, Bong-Jo, Lehrach, Hans, Leitão, Elsa, Lengauer, Thomas, Lernmark, Åke, Leung, Gilberto K.K., Leung, Danny, Ma, Yussanne, Martin-Subero, Jose Ignacio, Maschke, Karen, Merten, Christoph, Minucci, Saverio, Mitsuyama, Totai, Moore, Richard A., Nordström, Karl, Norstedt, Irene, Ouellette, Francis, Pap, Thomas, Pelicci, Pier Giuseppe, Phillips, Anthony G., Polansky, Julia, Pospisilik, J. Andrew, Prabhakar, Shyam, Procaccini, Dena C., Radbruch, Andreas, Rajewsky, Nikolaus, Rakyan, Vardham, Richardson, David, Rothstein, Mark, Sasaki, Hiroyuki, Sauer, Sascha, Schmidt, Florian, Schultze, Joachim L., Schulyer, Ronald P., Schulz, Marcel, Siebert, Reiner, Sinha, Anupam, Soranzo, Nicole, Spivakov, Mikhail, Steidl, Christian, Suzuki, Narumi, Torrents, David, Tyson, Frederick L., Ullrich, Sebastian, Ushijima, Toshikazu, Valencia, Alfonso, Wallace, Chris, Weber, Stephanie, Weiler, Nina, Weng, Andrew, Wilder, Steven, Yamashita, Yasuhiro, Yap, Desmond Y., Yip, Kevin Y., Yip, Stephen, Zerbino, Daniel, Zipprich, Gideon

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Clonal evolution of a case of treatment refractory maxillary sinus carcinoma von Arora, Shilpi, Korn, Ronald L, Lenkiewicz, Elizabeth, Cherni, Irene, Beach, Thomas G, Hostetter, Galen, Barrett, Michael T, Weiss, Glen J

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