BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors von Lee, Andrew, Mavaddat, Nasim, Wilcox, Amber N., Cunningham, Alex P., Carver, Tim, Hartley, Simon, Babb de Villiers, Chantal, Izquierdo, Angel, Simard, Jacques, Schmidt, Marjanka K., Walter, Fiona M., Chatterjee, Nilanjan, Garcia-Closas, Montserrat, Tischkowitz, Marc, Pharoah, Paul, Easton, Douglas F., Antoniou, Antonis C.

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CanRisk Tool-A Web Interface for the Prediction of Breast and Ovarian Cancer Risk and the Likelihood of Carrying Genetic Pathogenic Variants von Carver, Tim, Hartley, Simon, Lee, Andrew, Cunningham, Alex P, Archer, Stephanie, Babb de Villiers, Chantal, Roberts, Jonathan, Ruston, Rod, Walter, Fiona M, Tischkowitz, Marc, Easton, Douglas F, Antoniou, Antonis C

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Using human genetics to understand the disease impacts of testosterone in men and women von Ruth, Katherine S, Day, Felix R, Tyrrell, Jessica, Thompson, Deborah J, Wood, Andrew R, Mahajan, Anubha, Beaumont, Robin N, Wittemans, Laura, Martin, Susan, Busch, Alexander S., Erzurumluoglu, A. Mesut, Hollis, Benjamin, O’Mara, Tracy A., McCarthy, Mark I, Langenberg, Claudia, Easton, Douglas F, Wareham, Nicholas J, Burgess, Stephen, Murray, Anna, Ong, Ken K, Frayling, Timothy M, Perry, John R. B.

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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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Comprehensive functional annotation of 77 prostate cancer risk loci von Hazelett, Dennis J, Rhie, Suhn Kyong, Gaddis, Malaina, Yan, Chunli, Lakeland, Daniel L, Coetzee, Simon G, Henderson, Brian E, Noushmehr, Houtan, Cozen, Wendy, Kote-Jarai, Zsofia, Eeles, Rosalind A, Easton, Douglas F, Haiman, Christopher A, Lu, Wange, Farnham, Peggy J, Coetzee, Gerhard A

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A Systematic Genetic Assessment of 1,433 Sequence Variants of Unknown Clinical Significance in the BRCA1 and BRCA2 Breast Cancer–Predisposition Genes von Easton, Douglas F., Deffenbaugh, Amie M., Pruss, Dmitry, Frye, Cynthia, Wenstrup, Richard J., Allen-Brady, Kristina, Tavtigian, Sean V., Monteiro, Alvaro N.A., Iversen, Edwin S., Couch, Fergus J., Goldgar, David E.

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Cancer Incidence in BRCA1 Mutation Carriers von Thompson, Deborah, Easton, Douglas F.

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Genome-wide association studies in cancer von Easton, Douglas F., Eeles, Rosalind A.

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The BOADICEA model of genetic susceptibility to breast and ovarian cancer von Antoniou, A C, Pharoah, P P D, Smith, P, Easton, D F

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Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study von Archer, Stephanie, Babb de Villiers, Chantal, Scheibl, Fiona, Carver, Tim, Hartley, Simon, Lee, Andrew, Cunningham, Alex P, Easton, Douglas F, McIntosh, Jennifer G, Emery, Jon, Tischkowitz, Marc, Antoniou, Antonis C, Walter, Fiona M

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BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface von Lee, A J, Cunningham, A P, Kuchenbaecker, K B, Mavaddat, N, Easton, D F, Antoniou, A C

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Genetic susceptibility to breast cancer von Mavaddat, Nasim, Antoniou, Antonis C., Easton, Douglas F., Garcia-Closas, Montserrat

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Genome-wide association studies in common cancers—what have we learnt? von Varghese, Jajini Susan, Easton, Douglas F

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease von Rubinsztein, David C, Ravikumar, Brinda, Vacher, Coralie, Berger, Zdenek, Davies, Janet E, Luo, Shouqing, Oroz, Lourdes G, Scaravilli, Francesco, Easton, Douglas F, Duden, Rainer, O'Kane, Cahir J

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Combined quantitative measures of ER, PR, HER2, and KI67 provide more prognostic information than categorical combinations in luminal breast cancer von Abubakar, Mustapha, Figueroa, Jonine, Ali, H. Raza, Blows, Fiona, Lissowska, Jolanta, Caldas, Carlos, Easton, Douglas F., Sherman, Mark E., Garcia-Closas, Montserrat, Dowsett, Mitch, Pharoah, Paul D.

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EBCC-13 manifesto: Balancing pros and cons for contralateral prophylactic mastectomy von Schmidt, Marjanka K., Kelly, Jennifer E., Brédart, Anne, Cameron, David A., de Boniface, Jana, Easton, Douglas F., Offersen, Birgitte V., Poulakaki, Fiorita, Rubio, Isabel T., Sardanelli, Francesco, Schmutzler, Rita, Spanic, Tanja, Weigelt, Britta, Rutgers, Emiel J.T.

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The contribution of rare variation to prostate cancer heritability von Mancuso, Nicholas, Rohland, Nadin, Rand, Kristin A, Tandon, Arti, Allen, Alexander, Quinque, Dominique, Mallick, Swapan, Li, Heng, Stram, Alex, Sheng, Xin, Kote-Jarai, Zsofia, Easton, Douglas F, Eeles, Rosalind A, Le Marchand, Loic, Lubwama, Alex, Stram, Daniel, Watya, Stephen, Conti, David V, Henderson, Brian, Haiman, Christopher A, Pasaniuc, Bogdan, Reich, David

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Cancer Risks and Mortality in Heterozygous ATM Mutation Carriers von Thompson, Deborah, Duedal, Silvia, Kirner, Jennifer, McGuffog, Lesley, Last, James, Reiman, Anne, Byrd, Philip, Taylor, Malcolm, Easton, Douglas F.

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PALB2 , which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene von Rahman, Nazneen, Seal, Sheila, Thompson, Deborah, Kelly, Patrick, Renwick, Anthony, Elliott, Anna, Reid, Sarah, Spanova, Katarina, Barfoot, Rita, Chagtai, Tasnim, Jayatilake, Hiran, McGuffog, Lesley, Hanks, Sandra, Evans, D Gareth, Eccles, Diana, Easton, Douglas F, Stratton, Michael R

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The contributions of breast density and common genetic variation to breast cancer risk von Vachon, Celine M, Pankratz, V Shane, Scott, Christopher G, Haeberle, Lothar, Ziv, Elad, Jensen, Matthew R, Brandt, Kathleen R, Whaley, Dana H, Olson, Janet E, Heusinger, Katharina, Hack, Carolin C, Jud, Sebastian M, Beckmann, Matthias W, Schulz-Wendtland, Ruediger, Tice, Jeffrey A, Norman, Aaron D, Cunningham, Julie M, Purrington, Kristen S, Easton, Douglas F, Sellers, Thomas A, Kerlikowske, Karla, Fasching, Peter A, Couch, Fergus J

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