056 Leucocyte telomere/telomerase dynamics in patients with implantable cardioverter defibrillator; potential biomarker for ventricular arrhythmias: Abstract 056 Table 1 von Sawhney, V S, Campbell, N G C, Brouilette, S W B, Shintani, Y S, Coppen, S R C, Narita, T N, Ikebe, C I, Kaneko, M K, Yashiro, K Y, Baker, V B, Goromonzi, F G, Abbott, M A, Duncan, E D, Dhinoja, M D, Earley, M J E, Sporton, S S, Suzuki, K S, Schilling, R J S

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056 Leucocyte telomere/telomerase dynamics in patients with implantable cardioverter defibrillator; potential biomarker for ventricular arrhythmias von Sawhney, V S, Campbell, N G C, Brouilette, S W B, Shintani, Y S, Coppen, S R C, Narita, T N, Ikebe, C I, Kaneko, M K, Yashiro, K Y, Baker, V B, Goromonzi, F G, Abbott, M A, Duncan, E D, Dhinoja, M D, Earley, M J E, Sporton, S S, Suzuki, K S, Schilling, R J S

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Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels von Coste, Bertrand, Mathur, Jayanti, Schmidt, Manuela, Earley, Taryn J, Ranade, Sanjeev, Petrus, Matt J, Dubin, Adrienne E, Patapoutian, Ardem

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Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice von Puckelwartz, Megan J., Kessler, Eric, Zhang, Yuan, Hodzic, Didier, Randles, K. Natalie, Morris, Glenn, Earley, Judy U., Hadhazy, Michele, Holaska, James M., Mewborn, Stephanie K., Pytel, Peter, McNally, Elizabeth M.

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Validation of a novel mapping system and utility for mapping complex atrial tachycardias von Honarbakhsh, S., Hunter, R.J., Dhillon, G., Ullah, W., Keating, E., Providencia, R., Chow, A., Earley, M.J., Schilling, R.J.

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Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis von Schormair, Barbara, Zhao, Chen, Bell, Steven, Tilch, Erik, Salminen, Aaro V, Pütz, Benno, Dauvilliers, Yves, Stefani, Ambra, Högl, Birgit, Poewe, Werner, Kemlink, David, Sonka, Karel, Bachmann, Cornelius G, Paulus, Walter, Trenkwalder, Claudia, Oertel, Wolfgang H, Hornyak, Magdolna, Teder-Laving, Maris, Metspalu, Andres, Hadjigeorgiou, Georgios M, Polo, Olli, Fietze, Ingo, Ross, Owen A, Wszolek, Zbigniew, Butterworth, Adam S, Soranzo, Nicole, Ouwehand, Willem H, Roberts, David J, Danesh, John, Allen, Richard P, Earley, Christopher J, Ondo, William G, Xiong, Lan, Montplaisir, Jacques, Gan-Or, Ziv, Perola, Markus, Vodicka, Pavel, Dina, Christian, Franke, Andre, Tittmann, Lukas, Stewart, Alexandre F R, Shah, Svati H, Gieger, Christian, Peters, Annette, Rouleau, Guy A, Berger, Klaus, Oexle, Konrad, Di Angelantonio, Emanuele, Hinds, David A, Müller-Myhsok, Bertram, Winkelmann, Juliane, Balkau, B, Ducimetière, P, Eschwège, E, Rancière, F, Alhenc-Gelas, F, Gallois, Y, Girault, A, Fumeron, F, Marre, M, Roussel, R, Bonnet, F, Bonnefond, A, Cauchi, S, Froguel, P, Cogneau, J, Born, C, Caces, E, Cailleau, M, Lantieri, O, Moreau, JG, Rakotozafy, F, Tichet, J, Vol, S, Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K, Bryc, Katarzyna, Elson, Sarah L, Fontanillas, Pierre, Furlotte, Nicholas A, Hinds, David A, Hromatka, Bethann S, Huber, Karen E, Kleinman, Aaron, Litterman, Nadia K, McIntyre, Matthew H, Mountain, Joanna L, Northover, Carrie AM, Pitts, Steven J, Sathirapongsasuti, J Fah, Sazonova, Olga V, Shelton, Janie F, Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y, Vacic, Vladimir, Wilson, Catherine H

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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models von Kendsersky, Nathan M, Lindsay, Jarrett, Kolb, E Anders, Smith, Malcolm A, Teicher, Beverly A, Erickson, Stephen W, Earley, Eric J, Mosse, Yael P, Martinez, Daniel, Pogoriler, Jennifer, Krytska, Kateryna, Patel, Khushbu, Groff, David, Tsang, Matthew, Ghilu, Samson, Wang, Yifei, Seaman, Steven, Feng, Yang, Croix, Brad St, Gorlick, Richard, Kurmasheva, Raushan, Houghton, Peter J, Maris, John M

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Congenital leptin deficiency is associated with severe early-onset obesity in humans von O'Rahilly, Stephen, Montague, Carl T, Farooqi, I. Sadaf, Whitehead, Jonathan P, Soos, Maria A, Rau, Harald, Wareham, Nicholas J, Sewter, Ciaran P, Digby, Janet E, Mohammed, Shehla N, Hurst, Jane A, Cheetham#, Christopher H, Earley#, Alison R, Barnett, Anthony H, Prins, Johannes B

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Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury von Halbower, Ann C, Degaonkar, Mahaveer, Barker, Peter B, Earley, Christopher J, Marcus, Carole L, Smith, Philip L, Prahme, M Cristine, Mahone, E Mark

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A highly integrated bionic hand with neural control and feedback for use in daily life von Ortiz-Catalan, Max, Zbinden, Jan, Millenaar, Jason, D'Accolti, Daniele, Controzzi, Marco, Clemente, Francesco, Cappello, Leonardo, Earley, Eric J, Mastinu, Enzo, Kolankowska, Justyna, Munoz-Novoa, Maria, Jönsson, Stewe, Cipriani, Christian, Sassu, Paolo, Brånemark, Rickard

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Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren's Syndrome von Stone, Donald U, Fife, Dustin, Brown, Michael, Earley, Keith E, Radfar, Lida, Kaufman, C Erick, Lewis, David M, Rhodus, Nelson L, Segal, Barbara M, Wallace, Daniel J, Weisman, Michael H, Venuturupalli, Swamy, Brennan, Michael T, Lessard, Christopher J, Montgomery, Courtney G, Scofield, R Hal, Sivils, Kathy L, Rasmussen, Astrid

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A Propensity matched case-control study comparing efficacy, safety and costs of the Subcutaneous vs. Transvenous Implantable Cardioverter Defibrillator von Honarbakhsh, S, Providencia, R, Srinivasan, N, Ahsan, S, Lowe, M, Rowland, E, Hunter, RJ, Finlay, M, Segal, O, Earley, MJ, Chow, A, Schilling, RJ, Lambiase, PD

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Radiofrequency ablation of arrhythmias guided by non-fluoroscopic catheter location : a prospective randomized trial von DE PONTI, Roberto, SALERNO-URIARTE, Jorge A, SPORTON, Simon C, SCHILLING, Richard J, EARLEY, Mark J, SHOWKATHALI, Refai, ALZETANI, Maysaa, KISTLER, Peter M, GUPTA, Dhiraj, ABRAMS, Dominic J, HORROCKS, Julie A, HARRIS, Stuart J

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Brain iron deficiency in idiopathic restless legs syndrome measured by quantitative magnetic susceptibility at 7 tesla von Li, Xu, Allen, Richard P, Earley, Christopher J, Liu, Hongjun, Cruz, Tiana E, Edden, Richard A.E, Barker, Peter B, van Zijl, Peter C.M

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Long-term efficacy of catheter ablation for atrial fibrillation: impact of additional targeting of fractionated electrograms von Hunter, R J, Berriman, T J, Diab, I, Baker, V, Finlay, M, Richmond, L, Duncan, E, Kamdar, R, Thomas, G, Abrams, D, Dhinoja, M, Sporton, S, Earley, M J, Schilling, R J

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Left atrial scarring and conduction velocity dynamics: Rate dependent conduction slowing predicts sites of localized reentrant atrial tachycardias von Honarbakhsh, S., Schilling, R.J., Orini, M., Providencia, R., Finlay, M., Keating, E., Lambiase, P.D., Chow, A., Earley, M.J., Sporton, S., Hunter, R.J.

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A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia von Krivtsov, Andrei V., Evans, Kathryn, Gadrey, Jayant Y., Eschle, Benjamin K., Hatton, Charlie, Uckelmann, Hannah J., Ross, Kenneth N., Perner, Florian, Olsen, Sarah N., Pritchard, Tara, McDermott, Lisa, Jones, Connor D., Jing, Duohui, Braytee, Ali, Chacon, Diego, Earley, Eric, McKeever, Brian M., Claremon, David, Gifford, Andrew J., Lee, Heather J., Teicher, Beverly A., Pimanda, John E., Beck, Dominik, Perry, Jennifer A., Smith, Malcolm A., McGeehan, Gerard M., Lock, Richard B., Armstrong, Scott A.

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Normal myoblast fusion requires myoferlin von Doherty, Katherine R, Cave, Andrew, Davis, Dawn Belt, Delmonte, Anthony J, Posey, Avery, Earley, Judy U, Hadhazy, Michele, McNally, Elizabeth M

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An observational study on passive immunity in Irish suckler beef and dairy calves: Tests for failure of passive transfer of immunity and associations with health and performance von Todd, C.G., McGee, M., Tiernan, K., Crosson, P., O’Riordan, E., McClure, J., Lorenz, I., Earley, B.

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TRPV4 Forms a Novel Ca2+ Signaling Complex With Ryanodine Receptors and BKCa Channels von Earley, Scott, Heppner, Thomas J, Nelson, Mark T, Brayden, Joseph E

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