Future Therapeutics in Alzheimer’s Disease: Development Status of BACE Inhibitors von Evin, Genevieve

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β-Site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis von Tan, Jiangli, Evin, Geneviève

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BACE1 as a Therapeutic Target in Alzheimer’s Disease: Rationale and Current Status von Evin, Genevieve, Hince, Christopher

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Platelets and Alzheimer's disease: Potential of APP as a biomarker von Evin, Geneviève, Li, Qiao-Xin

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BACE: Therapeutic target and potential biomarker for Alzheimer's disease von Evin, Geneviève, Barakat, Adel, Masters, Colin L

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Mild oxidative stress induces redistribution of BACE1 in non-apoptotic conditions and promotes the amyloidogenic processing of Alzheimer's disease amyloid precursor protein von Tan, Jiang-Li, Li, Qiao-Xin, Ciccotosto, Giuseppe D, Crouch, Peter John, Culvenor, Janetta Gladys, White, Anthony Robert, Evin, Genevieve

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Decreased Neuregulin 1 C-terminal fragment in Brodmann's area 6 of patients with schizophrenia von Barakat, Adel, Dean, Brian, Scarr, Elizabeth, Evin, Geneviève

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Presenilins Promote the Cellular Uptake of Copper and Zinc and Maintain Copper Chaperone of SOD1-dependent Copper/Zinc Superoxide Dismutase Activity von Greenough, Mark A., Volitakis, Irene, Li, Qiao-Xin, Laughton, Katrina, Evin, Genevieve, Ho, Michael, Dalziel, Andrew H., Camakaris, James, Bush, Ashley I.

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Degradation of the Alzheimer Disease Amyloid β-Peptide by Metal-dependent Up-regulation of Metalloprotease Activity von White, Anthony R., Du, Tai, Laughton, Katrina M., Volitakis, Irene, Sharples, Robyn A., Xilinas, Michel E., Hoke, David E., Holsinger, R. M. Damian, Evin, Geneviève, Cherny, Robert A., Hill, Andrew F., Barnham, Kevin J., Li, Qiao-Xin, Bush, Ashley I., Masters, Colin L.

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Inhibition of γ-secretase as a therapeutic intervention for Alzheimer's disease: Prospects, limitations and strategies von EVIN, Geneviève, SERNEE, Marijke Fleur, MASTERS, Colin L

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Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein von Santosa, Claudia, Rasche, Stefanie, Barakat, Adel, Bellingham, Shayne A, Ho, Michael, Tan, Jiangli, Hill, Andrew F, Masters, Colin L, McLean, Catriona, Evin, Geneviève

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Levels of [3 H]pirenzepine binding in Brodmann's area 6 from subjects with schizophrenia is not associated with changes in the transcription factor SP1 or BACE1 von Dean, Brian, Soulby, Andrew, Evin, Geneviève M, Scarr, Elizabeth

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How accelerated Golgi trafficking may drive Alzheimer's disease (comment on DOI 10.1002/bies.201400116) von Evin, Genevieve

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Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate von Ho, Michael, Hoke, David E., Chua, Yee Jia, Li, Qiao-Xin, Culvenor, Janetta G., Masters, Colin L., White, Anthony R., Evin, Geneviève

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Amyloid blood biomarker detects Alzheimer’s disease prior to clinical onset von Evin, Genevieve

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APP intracellular domain is increased and soluble Aβ is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease von George, Amee J, Holsinger, R.M.Damian, McLean, Catriona A, Laughton, Katrina M, Beyreuther, Konrad, Evin, Genevieve, Masters, Colin L, Li, Qiao-Xin

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Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice von Chiocco, Matthew J, Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T

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Effects of Mild and Severe Oxidative Stress on BACE1 Expression and APP Amyloidogenic Processing von Tan, Jiangli, Li, Qiao-Xin, Evin, Genevieve

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γ-secretase modulators: hopes and setbacks for the future of Alzheimer's treatment von Evin, Genevieve

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A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing von Weidemann, Andreas, Eggert, Simone, Reinhard, Friedrich B. M, Vogel, Markus, Paliga, Krzysztof, Baier, Gottfried, Masters, Colin L, Beyreuther, Konrad, Evin, Geneviève

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