Comorbidities confound metabolomics studies of human disease von Jaagura, Madis, Kronberg, Jaanika, Reigo, Anu, Aasmets, Oliver, Nikopensius, Tiit, Võsa, Urmo, Bomba, Lorenzo, Estrada, Karol, Wuster, Arthur, Esko, Tõnu, Org, Elin

Volltext

Association between bone mineral density and type 2 diabetes mellitus: a meta-analysis of observational studies von Ma, Lili, Oei, Ling, Jiang, Lindi, Estrada, Karol, Chen, Huiyong, Wang, Zhen, Yu, Qiang, Zillikens, Maria Carola, Gao, Xin, Rivadeneira, Fernando

Volltext

Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease von Kappen, Jasper H, Medina-Gomez, Carolina, van Hagen, P Martin, Stolk, Lisette, Estrada, Karol, Rivadeneira, Fernando, Uitterlinden, Andre G, Stanford, Miles R, Ben-Chetrit, Eldat, Wallace, Graham R, Soylu, Merih, van Laar, Jan A M

Volltext

Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes von Schwartzentruber, Jeremy, Cooper, Sarah, Liu, Jimmy Z., Barrio-Hernandez, Inigo, Bello, Erica, Kumasaka, Natsuhiko, Young, Adam M. H., Franklin, Robin J. M., Johnson, Toby, Estrada, Karol, Gaffney, Daniel J., Beltrao, Pedro, Bassett, Andrew

Volltext

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases von Zheng, Jie, Haberland, Valeriia, Baird, Denis, Walker, Venexia, Haycock, Philip C., Hurle, Mark R., Gutteridge, Alex, Erola, Pau, Liu, Yi, Luo, Shan, Robinson, Jamie, Richardson, Tom G., Staley, James R., Elsworth, Benjamin, Burgess, Stephen, Sun, Benjamin B., Danesh, John, Runz, Heiko, Maranville, Joseph C., Martin, Hannah M., Yarmolinsky, James, Laurin, Charles, Holmes, Michael V., Liu, Jimmy Z., Estrada, Karol, Santos, Rita, McCarthy, Linda, Waterworth, Dawn, Nelson, Matthew R., Smith, George Davey, Butterworth, Adam S., Hemani, Gibran, Scott, Robert A., Gaunt, Tom R.

Volltext

BIN1 favors the spreading of Tau via extracellular vesicles von Crotti, Andrea, Sait, Hameetha Rajamohamend, McAvoy, Kathleen M., Estrada, Karol, Ergun, Ayla, Szak, Suzanne, Marsh, Galina, Jandreski, Luke, Peterson, Michael, Reynolds, Taylor L., Dalkilic-Liddle, Isin, Cameron, Andrew, Cahir-McFarland, Ellen, Ransohoff, Richard M.

Volltext

Benchmarking machine learning models for late-onset alzheimer's disease prediction from genomic data von De Velasco Oriol, Javier, Vallejo, Edgar E, Estrada, Karol, Taméz Peña, José Gerardo, Disease Neuroimaging Initiative, The Alzheimer's

Volltext

A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica von Estrada, Karol, Whelan, Christopher W., Zhao, Fengmei, Bronson, Paola, Handsaker, Robert E., Sun, Chao, Carulli, John P., Harris, Tim, Ransohoff, Richard M., McCarroll, Steven A., Day-Williams, Aaron G., Greenberg, Benjamin M., MacArthur, Daniel G.

Volltext

Phenome-wide association studies across large population cohorts support drug target validation von Diogo, Dorothée, Tian, Chao, Franklin, Christopher S., Alanne-Kinnunen, Mervi, March, Michael, Spencer, Chris C. A., Vangjeli, Ciara, Weale, Michael E., Mattsson, Hannele, Kilpeläinen, Elina, Sleiman, Patrick M. A., Reilly, Dermot F., McElwee, Joshua, Maranville, Joseph C., Chatterjee, Arnaub K., Bhandari, Aman, Nguyen, Khanh-Dung H., Estrada, Karol, Reeve, Mary-Pat, Hutz, Janna, Bing, Nan, John, Sally, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Hakonarson, Hakon, Daly, Mark J., Palotie, Aarno, Hinds, David A., Donnelly, Peter, Fox, Caroline S., Day-Williams, Aaron G., Plenge, Robert M., Runz, Heiko

Volltext

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome von Baird, Denis A, Liu, Jimmy Z, Zheng, Jie, Sieberts, Solveig K, Perumal, Thanneer, Elsworth, Benjamin, Richardson, Tom G, Chen, Chia-Yen, Carrasquillo, Minerva M, Allen, Mariet, Reddy, Joseph S, De Jager, Philip L, Ertekin-Taner, Nilufer, Mangravite, Lara M, Logsdon, Ben, Estrada, Karol, Haycock, Philip C, Hemani, Gibran, Runz, Heiko, Smith, George Davey, Gaunt, Tom R

Volltext

Challenges in conducting genome-wide association studies in highly admixed multi-ethnic populations: the Generation R Study von Medina-Gomez, Carolina, Felix, Janine Frédérique, Estrada, Karol, Peters, Marjoline Josephine, Herrera, Lizbeth, Kruithof, Claudia Jeanette, Duijts, Liesbeth, Hofman, Albert, van Duijn, Cornelia Marja, Uitterlinden, Andreas Gerardus, Jaddoe, Vincent Wilfred Vishal, Rivadeneira, Fernando

Volltext

A systematic review and functional bioinformatics analysis of genes associated with Crohn's disease identify more than 120 related genes von Garza-Hernandez, Debora, Sepulveda-Villegas, Maricruz, Garcia-Pelaez, Jose, Aguirre-Gamboa, Raul, Lakatos, Peter L, Estrada, Karol, Martinez-Vazquez, Manuel, Trevino, Victor

Volltext

Identifying therapeutic drug targets using bidirectional effect genes von Estrada, Karol, Froelich, Steven, Wuster, Arthur, Bauer, Christopher R., Sterling, Teague, Clark, Wyatt T., Ru, Yuanbin, Trinidad, Marena, Nguyen, Hong Phuc, Luu, Amanda R., Wendt, Daniel J., Yogalingam, Gouri, Yu, Guoying Karen, LeBowitz, Jonathan H., Cardon, Lon R.

Volltext

Common variants at ten loci influence QT interval duration in the QTGEN Study von Newton-Cheh, Christopher, Kors, Jan A, de Bakker, Paul I W, Witteman, Jacqueline C M, Estrada, Karol, Heckbert, Susan R, Uitterlinden, André G, Smith, Nicholas L, Eijgelsheim, Mark, Lumley, Thomas, Ch Stricker, Bruno H, O'Donnell, Christopher J, Rice, Kenneth M, Sotoodehnia, Nona, Larson, Martin G, Yin, Xiaoyan, Noseworthy, Peter A, Bis, Joshua C, Hofman, Albert, Marciante, Kristin, Rotter, Jerome I, Rivadeneira, Fernando, Psaty, Bruce M

Volltext

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche von Stolk, Lisette, Murabito, Joanne M, Rivadeneira, Fernando, Boerwinkle, Eric, Ferrucci, Luigi, Nalls, Michael A, Shuldiner, Alan R, Bandinelli, Stefania, Kiel, Douglas P, Harris, Tamara B, Spector, Tim D, Folsom, Aaron R, Murray, Anna, Lunetta, Kathryn L, Aspelund, Thor, Weedon, Michael N, van Meurs, Joyce, Visser, Jenny A, Garcia, Melissa, Zhuang, Vivian, Gudnason, Vilmundur, Singleton, Andrew, Zhai, Guangju, McArdle, Patrick F, Launer, Lenore J, Soranzo, Nicole, Streeten, Elizabeth A, Hofman, Albert, Demerath, Ellen W, Wilson, Scott G, Estrada, Karol, Uitterlinden, André G, Eiriksdottir, Gudny, Karasik, David, Tanaka, Toshiko, Franceschini, Nora, Perry, John R B, Smith, Albert V, Cherkas, Lynn

Volltext

Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands' von Deelen, Patrick, Menelaou, Androniki, van Leeuwen, Elisabeth M, Kanterakis, Alexandros, van Dijk, Freerk, Medina-Gomez, Carolina, Francioli, Laurent C, Hottenga, Jouke Jan, Karssen, Lennart C, Estrada, Karol, Kreiner-Møller, Eskil, Rivadeneira, Fernando, van Setten, Jessica, Gutierrez-Achury, Javier, Westra, Harm-Jan, Franke, Lude, van Enckevort, David, Dijkstra, Martijn, Byelas, Heorhiy, van Duijn, Cornelia M, de Bakker, Paul I W, Wijmenga, Cisca, Swertz, Morris A

Volltext

Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus von Medina-Gomez, Carolina, Kemp, John P, Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M, Heppe, Denise H M, Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M, Kruithof, Claudia J, Timpson, Nicholas J, Zillikens, M Carola, Olstad, Ole K, Zheng, Hou-Feng, Richards, J Brent, St Pourcain, Beate, Hofman, Albert, Jaddoe, Vincent W V, Smith, George Davey, Lorentzon, Mattias, Gautvik, Kaare M, Uitterlinden, André G, Brommage, Robert, Ohlsson, Claes, Tobias, Jonathan H, Rivadeneira, Fernando

Volltext

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits von Hsu, Yi-Hsiang, Zillikens, M Carola, Wilson, Scott G, Farber, Charles R, Demissie, Serkalem, Soranzo, Nicole, Bianchi, Estelle N, Grundberg, Elin, Liang, Liming, Richards, J Brent, Estrada, Karol, Zhou, Yanhua, van Nas, Atila, Moffatt, Miriam F, Zhai, Guangju, Hofman, Albert, van Meurs, Joyce B, Pols, Huibert A P, Price, Roger I, Nilsson, Olle, Pastinen, Tomi, Cupples, L Adrienne, Lusis, Aldons J, Schadt, Eric E, Ferrari, Serge, Uitterlinden, André G, Rivadeneira, Fernando, Spector, Timothy D, Karasik, David, Kiel, Douglas P

Volltext

Loci at chromosomes 13, 19 and 20 influence age at natural menopause von Stolk, Lisette, Deloukas, Panos, Laven, Joop S E, van Meurs, Joyce B J, Verbiest, Michael M P J, Witteman, Jacqueline, Estrada, Karol, Uitterlinden, André G, Pop, Victor J M, Cherkas, Lynn, Pols, Huibert A P, Lips, Paul, Lebrun, Corinne E I, Soranzo, Nicole, de Keyzer, Jules J, van der Schouw, Yvonne T, Hofman, Albert, Williams, Frances M, Grobbee, Diederick E, Rivadeneira, Fernando, Visser, Jenny A, Zhai, Guangju, Spector, Tim D

Volltext

Association of a Genetic Risk Score With Body Mass Index Across Different Birth Cohorts von Walter, Stefan, Mejía-Guevara, Iván, Estrada, Karol, Liu, Sze Y, Glymour, M. Maria

Volltext