Generation of SARS-CoV-2 reporter replicon for high-throughput antiviral screening and testing von He, Xi, Quan, Shuo, Xu, Min, Rodriguez, Silveria, Goh, Shih Lin, Wei, Jiajie, Fridman, Arthur, Koeplinger, Kenneth A., Carroll, Steve S., Grobler, Jay A., Espeseth, Amy S., Olsen, David B., Hazuda, Daria J., Wang, Dai

Volltext

Host cell factors in HIV replication: meta-analysis of genome-wide studies von Bushman, Frederic D, Malani, Nirav, Fernandes, Jason, D'Orso, Iván, Cagney, Gerard, Diamond, Tracy L, Zhou, Honglin, Hazuda, Daria J, Espeseth, Amy S, König, Renate, Bandyopadhyay, Sourav, Ideker, Trey, Goff, Stephen P, Krogan, Nevan J, Frankel, Alan D, Young, John A T, Chanda, Sumit K

Volltext

A phase 1, randomized, placebo-controlled study to evaluate the safety and immunogenicity of an mRNA-based RSV prefusion F protein vaccine in healthy younger and older adults von Aliprantis, Antonios O., Shaw, Christine A., Griffin, Paul, Farinola, Nicholas, Railkar, Radha A., Cao, Xin, Liu, Wen, Sachs, Jeffrey R., Swenson, Christine J., Lee, Heather, Cox, Kara S., Spellman, Daniel S., Winstead, Colleen J., Smolenov, Igor, Lai, Eseng, Zaks, Tal, Espeseth, Amy S., Panther, Lori

Volltext

Genome-scale RNAi screen for host factors required for HIV replication von Zhou, Honglin, Xu, Min, Huang, Qian, Gates, Adam T, Zhang, Xiaohua D, Castle, John C, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Hazuda, Daria J, Espeseth, Amy S

Volltext

Pentameric complex of viral glycoprotein H is the primary target for potent neutralization by a human cytomegalovirus vaccine von Freed, Daniel C, Tang, Qi, Tang, Aimin, Li, Fengsheng, He, Xi, Huang, Zhao, Meng, Weixu, Xia, Lin, Finnefrock, Adam C, Durr, Eberhard, Espeseth, Amy S, Casimiro, Danilo R, Zhang, Ningyan, Shiver, John W, Wang, Dai, An, Zhiqiang, Fu, Tong-Ming

Volltext

Modified mRNA/lipid nanoparticle-based vaccines expressing respiratory syncytial virus F protein variants are immunogenic and protective in rodent models of RSV infection von Espeseth, Amy S., Cejas, Pedro J., Citron, Michael P., Wang, Dai, DiStefano, Daniel J., Callahan, Cheryl, Donnell, Gregory O’, Galli, Jennifer D., Swoyer, Ryan, Touch, Sinoeun, Wen, Zhiyun, Antonello, Joseph, Zhang, Lan, Flynn, Jessica A., Cox, Kara S., Freed, Daniel C., Vora, Kalpit A., Bahl, Kapil, Latham, Andrew H., Smith, Jeffrey S., Gindy, Marian E., Ciaramella, Giuseppe, Hazuda, Daria, Shaw, Christine A., Bett, Andrew J.

Volltext

Selective HDAC inhibition for the disruption of latent HIV-1 infection von Barton, Kirston M, Archin, Nancie M, Keedy, Kara S, Espeseth, Amy S, Zhang, Yan-ling, Gale, Jennifer, Wagner, Florence F, Holson, Edward B, Margolis, David M

Volltext

Identification of adipocyte plasma membrane-associated protein as a novel modulator of human cytomegalovirus infection von Ye, Xiaohua, Gui, Xun, Freed, Daniel C, Ku, Zhiqiang, Li, Leike, Chen, Yuanzhi, Xiong, Wei, Fan, Xuejun, Su, Hang, He, Xi, Rustandi, Richard R, Loughney, John W, Ma, Ningning, Espeseth, Amy S, Liu, Jian, Zhu, Hua, Wang, Dai, Zhang, Ningyan, Fu, Tong-Ming, An, Zhiqiang

Volltext

Stability Characterization of a Vaccine Antigen Based on the Respiratory Syncytial Virus Fusion Glycoprotein von Flynn, Jessica A, Durr, Eberhard, Swoyer, Ryan, Cejas, Pedro J, Horton, Melanie S, Galli, Jennifer D, Cosmi, Scott A, Espeseth, Amy S, Bett, Andrew J, Zhang, Lan

Volltext

Forward and reverse translational approaches to predict efficacy of neutralizing respiratory syncytial virus (RSV) antibody prophylaxis von Maas, Brian M., Lommerse, Jos, Plock, Nele, Railkar, Radha A., Cheung, S.Y. Amy, Caro, Luzelena, Chen, Jingxian, Liu, Wen, Zhang, Ying, Huang, Qinlei, Gao, Wei, Qin, Li, Meng, Jie, Witjes, Han, Schindler, Emilie, Guiastrennec, Benjamin, Bellanti, Francesco, Spellman, Daniel S., Roadcap, Brad, Kalinova, Mariya, Fok-Seang, Juin, Catchpole, Andrew P., Espeseth, Amy S., Stoch, S. Aubrey, Lai, Eseng, Vora, Kalpit A., Aliprantis, Antonios O., Sachs, Jeffrey R.

Volltext

siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration von Espeseth, Amy S, Fishel, Rick, Hazuda, Daria, Huang, Qian, Xu, Min, Yoder, Kristine, Zhou, Honglin

Volltext

Diketo Acid Inhibitor Mechanism and HIV-1 Integrase: Implications for Metal Binding in the Active Site of Phosphotransferase Enzymes von Grobler, Jay A., Stillmock, Kara, Hu, Binghua, Witmer, Marc, Felock, Peter, Espeseth, Amy S., Wolfe, Abigail, Egbertson, Melissa, Bourgeois, Michele, Melamed, Jeffrey, Wai, John S., Young, Steve, Vacca, Joseph, Hazuda, Daria J.

Volltext

Transplacental Antibody Transfer of Respiratory Syncytial Virus Specific IgG in Non-Human Primate Mother-Infant Pairs von Citron, Michael P., McAnulty, Jessica, Callahan, Cheryl, Knapp, Walter, Fontenot, Jane, Morales, Pablo, Flynn, Jessica A., Douglas, Cameron M., Espeseth, Amy S.

Volltext

HIV-1 Integrase Inhibitors That Compete with the Target DNA Substrate Define a Unique Strand Transfer Conformation for Integrase von Espeseth, Amy S., Felock, Peter, Wolfe, Abigail, Witmer, Marc, Grobler, Jay, Anthony, Neville, Egbertson, Melissa, Melamed, Jeffrey Y., Young, Steve, Hamill, Terence, Cole, James L., Hazuda, Daria J.

Volltext

Upper and lower respiratory tract correlates of protection against respiratory syncytial virus following vaccination of nonhuman primates von Zohar, Tomer, Hsiao, Jeff C., Mehta, Nickita, Das, Jishnu, Devadhasan, Anush, Karpinski, Wiktor, Callahan, Cheryl, Citron, Michael P., DiStefano, Daniel J., Touch, Sinoeun, Wen, Zhiyun, Sachs, Jeffrey R., Cejas, Pedro J., Espeseth, Amy S., Lauffenburger, Douglas A., Bett, Andrew J., Alter, Galit

Volltext

Novel adjuvants enhance immune responses elicited by a replication-defective human cytomegalovirus vaccine in nonhuman primates von Li, Hualin, Monslow, Morgan A., Freed, Daniel C., Chang, Dan, Li, Fengsheng, Gindy, Marian, Wang, Dai, Vora, Kalpit, Espeseth, Amy S., Petrovsky, Nikolai, Fu, Tong-Ming

Volltext

The Use of Strictly Standardized Mean Difference for Hit Selection in Primary RNA Interference High-Throughput Screening Experiments von Zhang, Xiaohua Douglas, Ferrer, Marc, Espeseth, Amy S., Marine, Shane Douglas, Stec, Erica M., Crackower, Michael A., Holder, Daniel J., Heyse, Joseph F., Strulovici, Berta

Volltext

A Replication-Defective Human Cytomegalovirus Vaccine Elicits Humoral Immune Responses Analogous to Those with Natural Infection von Liu, Yaping, Freed, Daniel C, Li, Leike, Tang, Aimin, Li, Fengsheng, Murray, Edward M, Adler, Stuart P, McVoy, Michael A, Rupp, Richard E, Barrett, Diane, Ye, Xiaohua, Zhang, Ningyan, Beck, Karen, Culp, Timothy, Das, Rituparna, Song, Liping, Vora, Kalpit, Zhu, Hua, Wang, Dai, Espeseth, Amy S, An, Zhiqiang, Musey, Luwy, Fu, Tong-Ming

Volltext

Characterization of humoral and cell-mediated immunity induced by mRNA vaccines expressing influenza hemagglutinin stem and nucleoprotein in mice and nonhuman primates von Flynn, Jessica A., Weber, Teresa, Cejas, Pedro J., Cox, Kara S., Touch, Sinoeun, Austin, Lauren A., Ou, Yangsi, Citron, Michael P., Luo, Bin, Gindy, Marian E., Bahl, Kapil, Ciaramella, Giuseppe, Espeseth, Amy S., Zhang, Lan

Volltext

Evaluation of a stabilized RSV pre-fusion F mRNA vaccine: Preclinical studies and Phase 1 clinical testing in healthy adults von Nussbaum, Jesse, Cao, Xin, Railkar, Radha A., Sachs, Jeffrey R., Spellman, Daniel S., Luk, Julie, Shaw, Christine A., Cejas, Pedro J., Citron, Michael P., Al-Ibrahim, Mohamed, Han, David, Pagnussat, Sandra, Stoch, S. Aubrey, Lai, Eseng, Bett, Andrew J., Espeseth, Amy S.

Volltext