A Portrait of Alzheimer Secretases: New Features and Familiar Faces von Esler, William P., Wolfe, Michael S.

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Point Substitution in the Central Hydrophobic Cluster of a Human β-Amyloid Congener Disrupts Peptide Folding and Abolishes Plaque Competence von Esler, William P, Stimson, Evelyn R, Ghilardi, Joseph R, Lu, Yi-An, Felix, Arthur M, Vinters, Harry V, Mantyh, Patrick W, Lee, Jonathan P, Maggio, John E

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Activity-Dependent Isolation of the Presenilin- γ-Secretase Complex Reveals Nicastrin and a γ Substrate von Esler, William P., Kimberly, W. Taylor, Ostaszewski, Beth L., Ye, Wenjuan, Diehl, Thekla S., Selkoe, Dennis J., Wolfe, Michael S.

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Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1 von Esler, William P., Kimberly, W. Taylor, Ostaszewski, Beth L., Diehl, Thekla S., Moore, Chad L., Tsai, Jui-Yi, Rahmati, Talat, Xia, Weiming, Selkoe, Dennis J., Wolfe, Michael S.

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Alzheimer's Disease Amyloid Propagation by a Template-Dependent Dock-Lock Mechanism von Esler, William P, Stimson, Evelyn R, Jennings, Joan M, Vinters, Harry V, Ghilardi, Joseph R, Lee, Jonathan P, Mantyh, Patrick W, Maggio, John E

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Zinc‐Induced Aggregation of Human and Rat β‐Amyloid Peptides In Vitro von Esler, William P., Stimson, Evelyn R., Jennings, Joan M., Ghilardi, Joseph R., Mantyh, Patrick W., Maggio, John E.

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Fibrillar beta -Amyloid Induces Microglial Phagocytosis, Expression of Inducible Nitric Oxide Synthase, and Loss of a Select Population of Neurons in the Rat CNS In Vivo von Weldon, Derik T, Rogers, Scott D, Ghilardi, Joseph R, Finke, Matthew P, Cleary, James P, O'Hare, Eugene, Esler, William P, Maggio, John E, Mantyh, Patrick W

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Aβ deposition inhibitor screen using synthetic amyloid von ESLER, W. P, STIMSON, E. R, GHILARDI, J. R, FELIX, A. M, LU, Y.-A, VINTERS, H. V, MANTYH, P. W, MAGGIO, J. E

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Notch and the Amyloid Precursor Protein Are Cleaved by Similar γ-Secretase(s) von Kimberly, W. Taylor, Esler, William P, Ye, Wenjuan, Ostaszewski, Beth L, Gao, Jun, Diehl, Thekla, Selkoe, Dennis J, Wolfe, Michael S

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Deposition of Monomeric, Not Oligomeric, Aβ Mediates Growth of Alzheimer's Disease Amyloid Plaques in Human Brain Preparations von Tseng, Bertrand P, Esler, William P, Clish, Clary B, Stimson, Evelyn R, Ghilardi, Joseph R, Vinters, Harry V, Mantyh, Patrick W, Lee, Jonathan P, Maggio, John E

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In Vitro Growth of Alzheimer's Disease β-Amyloid Plaques Displays First-Order Kinetics von Esler, William P, Stimson, Evelyn R, Ghilardi, Joseph R, Vinters, Harry V, Lee, Jonathan P, Mantyh, Patrick W, Maggio, John E

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Activation Barriers to Structural Transition Determine Deposition Rates of Alzheimer's Disease Aβ Amyloid von Esler, William P., Felix, Arthur M., Stimson, Evelyn R., Lachenmann, Marcel J., Ghilardi, Joseph R., Lu, Yi-An, Vinters, Harry V., Mantyh, Patrick W., Lee, Jonathan P., Maggio, John E.

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Continuing strategies for inhibiting Alzheimer's gamma-secretase von Wolfe, Michael S, Esler, William P, Das, Chittaranjan

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[23] Deposition of soluble amyloid-β onto amyloid templates: With application for the identification of amyloid fibril extension inhibitors von Esler, William P., Stimson, Evelyn R., Mantyh, Patrick W., Maggio, John E.

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γ‐Secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila von Micchelli, Craig A., Esler, William P., Kimberly, W. Taylor, Jack, Christine, Berezovska, Oksana, Kornilova, Anna, Hyman, Bradley T., Perrimon, Norbert, Wolfe, Michael S.

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Stereochemical specificity of Alzheimer's disease β-peptide assembly von Esler, William P., Stimson, Evelyn R., Fishman, Jordan B., Ghilardi, Joseph R., Vinters, Harry V., Mantyh, Patrick W., Maggio, John E.

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Amyloid-lowering isocoumarins are not direct inhibitors of γ-secretase von Esler, William P, Das, Chittaranjan, Campbell, William A, Kimberly, W. Taylor, Kornilova, Anna Y, Diehl, Thekla S, Ye, Wenjuan, Ostaszewski, Beth L, Xia, Weiming, Selkoe, Dennis J, Wolfe, Michael S

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Zinc and Alzheimer's Disease von Fitzgerald, D. James, Maggio, John E., Esler, William P., Stimson, Evelyn R., Jennings, Joan M., Ghilardi, Joseph R., Mantyh, Patrick W., Bush, Ashley I., Moir, Robert D., Rosenkranz, Kari M., Tanzi, Rudolph E.

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Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations von Tseng, B P, Esler, W P, Clish, C B, Stimson, E R, Ghilardi, J R, Vinters, H V, Mantyh, P W, Lee, J P, Maggio, J E

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Apolipoprotein E affects amyloid formation but not amyloid growth in vitro: Mechanistic implications for ApoE4 enhanced amyloid burden and risk for Alzheimer's disease von Esler, William P., Marshall, Jeffrey R., Stimson, Evelyn R., Ghilardi, Joseph R., Vinters, Harry V., Mantyh, Patrick W., Maggio, John E.

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