Improved polygenic prediction by Bayesian multiple regression on summary statistics von Lloyd-Jones, Luke R., Zeng, Jian, Sidorenko, Julia, Yengo, Loïc, Moser, Gerhard, Kemper, Kathryn E., Wang, Huanwei, Zheng, Zhili, Magi, Reedik, Esko, Tõnu, Metspalu, Andres, Wray, Naomi R., Goddard, Michael E., Yang, Jian, Visscher, Peter M.

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Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu von Leitsalu, Liis, Haller, Toomas, Esko, Tõnu, Tammesoo, Mari-Liis, Alavere, Helene, Snieder, Harold, Perola, Markus, Ng, Pauline C, Mägi, Reedik, Milani, Lili, Fischer, Krista, Metspalu, Andres

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA von Kettunen, Johannes, Demirkan, Ayşe, Würtz, Peter, Draisma, Harmen H.M., Haller, Toomas, Rawal, Rajesh, Vaarhorst, Anika, Kangas, Antti J., Lyytikäinen, Leo-Pekka, Pirinen, Matti, Pool, René, Sarin, Antti-Pekka, Soininen, Pasi, Tukiainen, Taru, Wang, Qin, Tiainen, Mika, Tynkkynen, Tuulia, Amin, Najaf, Zeller, Tanja, Beekman, Marian, Deelen, Joris, van Dijk, Ko Willems, Esko, Tõnu, Hottenga, Jouke-Jan, van Leeuwen, Elisabeth M, Lehtimäki, Terho, Mihailov, Evelin, Rose, Richard J., de Craen, Anton J.M., Gieger, Christian, Kähönen, Mika, Perola, Markus, Blankenberg, Stefan, Savolainen, Markku J., Verhoeven, Aswin, Viikari, Jorma, Willemsen, Gonneke, Boomsma, Dorret I., van Duijn, Cornelia M., Eriksson, Johan, Jula, Antti, Järvelin, Marjo-Riitta, Kaprio, Jaakko, Metspalu, Andres, Raitakari, Olli, Salomaa, Veikko, Slagboom, P. Eline, Waldenberger, Melanie, Ripatti, Samuli, Ala-Korpela, Mika

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Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants von Tsoi, Lam C., Stuart, Philip E., Tian, Chao, Gudjonsson, Johann E., Das, Sayantan, Zawistowski, Matthew, Ellinghaus, Eva, Barker, Jonathan N., Chandran, Vinod, Dand, Nick, Duffin, Kristina Callis, Enerbäck, Charlotta, Esko, Tõnu, Franke, Andre, Gladman, Dafna D., Hoffmann, Per, Kingo, Külli, Kõks, Sulev, Krueger, Gerald G., Lim, Henry W., Metspalu, Andres, Mrowietz, Ulrich, Mucha, Sören, Rahman, Proton, Reis, Andre, Tejasvi, Trilokraj, Trembath, Richard, Voorhees, John J., Weidinger, Stephan, Weichenthal, Michael, Wen, Xiaoquan, Eriksson, Nicholas, Kang, Hyun M., Hinds, David A., Nair, Rajan P., Abecasis, Gonçalo R., Elder, James T

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A cross-disorder dosage sensitivity map of the human genome von Collins, Ryan L., Glessner, Joseph T., Porcu, Eleonora, Lepamets, Maarja, Brandon, Rhonda, Lauricella, Christopher, Han, Lide, Morley, Theodore, Niestroj, Lisa-Marie, Ulirsch, Jacob, Everett, Selin, Howrigan, Daniel P., Boone, Philip M., Fu, Jack, Karczewski, Konrad J., Kellaris, Georgios, Lowther, Chelsea, Lucente, Diane, Mohajeri, Kiana, Nõukas, Margit, Nuttle, Xander, Samocha, Kaitlin E., Trinh, Mi, Ullah, Farid, Võsa, Urmo, Metspalu, Andres, Mägi, Reedik, Nelis, Mari, Milani, Lili, Esko, Tõnu, Hurles, Matthew E., Aradhya, Swaroop, Davis, Erica E., Finucane, Hilary, Gusella, James F., Janze, Aura, Katsanis, Nicholas, Matyakhina, Ludmila, Neale, Benjamin M., Sanders, David, Warren, Stephanie, Hodge, Jennelle C., Lal, Dennis, Ruderfer, Douglas M., Meck, Jeanne, Mägi, Reedik, Esko, Tõnu, Reymond, Alexandre, Kutalik, Zoltán, Hakonarson, Hakon, Sunyaev, Shamil, Brand, Harrison, Talkowski, Michael E.

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Systematic identification of trans eQTLs as putative drivers of known disease associations von Westra, Harm-Jan, Peters, Marjolein J, Esko, Tõnu, Yaghootkar, Hanieh, Schurmann, Claudia, Kettunen, Johannes, Christiansen, Mark W, Fairfax, Benjamin P, Schramm, Katharina, Powell, Joseph E, Zhernakova, Alexandra, Zhernakova, Daria V, Veldink, Jan H, Van den Berg, Leonard H, Karjalainen, Juha, Withoff, Sebo, Uitterlinden, André G, Hofman, Albert, Rivadeneira, Fernando, 't Hoen, Peter A C, Reinmaa, Eva, Fischer, Krista, Nelis, Mari, Milani, Lili, Melzer, David, Ferrucci, Luigi, Singleton, Andrew B, Hernandez, Dena G, Nalls, Michael A, Homuth, Georg, Nauck, Matthias, Radke, Dörte, Völker, Uwe, Perola, Markus, Salomaa, Veikko, Brody, Jennifer, Suchy-Dicey, Astrid, Gharib, Sina A, Enquobahrie, Daniel A, Lumley, Thomas, Montgomery, Grant W, Makino, Seiko, Prokisch, Holger, Herder, Christian, Roden, Michael, Grallert, Harald, Meitinger, Thomas, Strauch, Konstantin, Li, Yang, Jansen, Ritsert C, Visscher, Peter M, Knight, Julian C, Psaty, Bruce M, Ripatti, Samuli, Teumer, Alexander, Frayling, Timothy M, Metspalu, Andres, van Meurs, Joyce B J, Franke, Lude

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Educational Attainment and Personality Are Genetically Intertwined von Mõttus, René, Realo, Anu, Vainik, Uku, Allik, Jüri, Esko, Tõnu

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Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel von Mitt, Mario, Kals, Mart, Pärn, Kalle, Gabriel, Stacey B, Lander, Eric S, Palotie, Aarno, Ripatti, Samuli, Morris, Andrew P, Metspalu, Andres, Esko, Tõnu, Mägi, Reedik, Palta, Priit

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Genotype-first approach to the detection of hereditary breast and ovarian cancer risk, and effects of risk disclosure to biobank participants von Leitsalu, Liis, Palover, Marili, Sikka, Timo Tonis, Reigo, Anu, Kals, Mart, Parn, Kalle, Nikopensius, Tiit, Esko, Tonu, Metspalu, Andres, Padrik, Peeter, Tonisson, Neeme

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Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan von Joshi, Peter K., Fischer, Krista, Schraut, Katharina E., Campbell, Harry, Esko, Tõnu, Wilson, James F.

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Genome-wide association study identifies five risk loci for pernicious anemia von Laisk, Triin, Lepamets, Maarja, Koel, Mariann, Abner, Erik, Mägi, Reedik

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Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes von Xue, Angli, Wu, Yang, Zhu, Zhihong, Zhang, Futao, Kemper, Kathryn E., Zheng, Zhili, Yengo, Loic, Lloyd-Jones, Luke R., Sidorenko, Julia, Wu, Yeda, McRae, Allan F., Visscher, Peter M., Zeng, Jian, Yang, Jian

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Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study von Gagnon, Eloi, Mitchell, Patricia L, Manikpurage, Hasanga D, Abner, Erik, Taba, Nele, Esko, Tõnu, Ghodsian, Nooshin, Thériault, Sébastien, Mathieu, Patrick, Arsenault, Benoit J

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Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons von Fischer, Krista, Kettunen, Johannes, Würtz, Peter, Haller, Toomas, Havulinna, Aki S, Kangas, Antti J, Soininen, Pasi, Esko, Tõnu, Tammesoo, Mari-Liis, Mägi, Reedik, Smit, Steven, Palotie, Aarno, Ripatti, Samuli, Salomaa, Veikko, Ala-Korpela, Mika, Perola, Markus, Metspalu, Andres

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Long-range regulatory effects of Neandertal DNA in modern humans von Yermakovich, Danat, Pankratov, Vasili, Võsa, Urmo, Yunusbayev, Bayazit, Dannemann, Michael

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Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells von Kasela, Silva, Kisand, Kai, Tserel, Liina, Kaleviste, Epp, Remm, Anu, Fischer, Krista, Esko, Tõnu, Westra, Harm-Jan, Fairfax, Benjamin P, Makino, Seiko, Knight, Julian C, Franke, Lude, Metspalu, Andres, Peterson, Pärt, Milani, Lili

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Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood von Qi, Ting, Wu, Yang, Zeng, Jian, Zhang, Futao, Xue, Angli, Jiang, Longda, Zhu, Zhihong, Kemper, Kathryn, Yengo, Loic, Zheng, Zhili, Marioni, Riccardo E., Montgomery, Grant W., Deary, Ian J., Wray, Naomi R., Visscher, Peter M., McRae, Allan F., Yang, Jian

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Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci von Ellinghaus, David, Ellinghaus, Eva, Nair, Rajan P., Stuart, Philip E., Esko, Tõnu, Metspalu, Andres, Debrus, Sophie, Raelson, John V., Tejasvi, Trilokraj, Belouchi, Majid, West, Sarah L., Barker, Jonathan N., Kõks, Sulev, Kingo, Külli, Balschun, Tobias, Palmieri, Orazio, Annese, Vito, Gieger, Christian, Wichmann, H. Erich, Kabesch, Michael, Trembath, Richard C., Mathew, Christopher G., Abecasis, Gonçalo R., Weidinger, Stephan, Nikolaus, Susanna, Schreiber, Stefan, Elder, James T., Weichenthal, Michael, Nothnagel, Michael, Franke, Andre

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Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification von Läll, Kristi, Lepamets, Maarja, Palover, Marili, Esko, Tõnu, Metspalu, Andres, Tõnisson, Neeme, Padrik, Peeter, Mägi, Reedik, Fischer, Krista

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Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients von Patrick, Matthew T., Stuart, Philip E., Raja, Kalpana, Gudjonsson, Johann E., Tejasvi, Trilokraj, Yang, Jingjing, Chandran, Vinod, Das, Sayantan, Callis-Duffin, Kristina, Ellinghaus, Eva, Enerbäck, Charlotta, Esko, Tõnu, Franke, Andre, Kang, Hyun M., Krueger, Gerald G., Lim, Henry W., Rahman, Proton, Rosen, Cheryl F., Weidinger, Stephan, Weichenthal, Michael, Wen, Xiaoquan, Voorhees, John J., Abecasis, Gonçalo R., Gladman, Dafna D., Nair, Rajan P., Elder, James T., Tsoi, Lam C.

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