A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals von Kirkland, David, Levy, Dan D., LeBaron, Matthew J., Aardema, Marilyn J., Beevers, Carol, Bhalli, Javed, Douglas, George R., Escobar, Patricia A., Farabaugh, Christopher S., Guerard, Melanie, Johnson, George E., Kulkarni, Rohan, Le Curieux, Frank, Long, Alexandra S., Lott, Jasmin, Lovell, David P., Luijten, Mirjam, Marchetti, Francesco, Nicolette, John J., Pfuhler, Stefan, Roberts, Daniel J., Stankowski, Leon F., Thybaud, Veronique, Weiner, Sandy K., Williams, Andrew, Witt, Kristine L., Young, Robert

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JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: I. Summary of pre-validation study results von Uno, Yoshifumi, Kojima, Hajime, Omori, Takashi, Corvi, Raffaella, Honma, Masamistu, Schechtman, Leonard M., Tice, Raymond R., Burlinson, Brian, Escobar, Patricia A., Kraynak, Andrew R., Nakagawa, Yuzuki, Nakajima, Madoka, Pant, Kamala, Asano, Norihide, Lovell, David, Morita, Takeshi, Ohno, Yasuo, Hayashi, Makoto

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Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following expos... von Bercu, Joel P., Zhang, Shaofei, Sobol, Zhanna, Escobar, Patricia A., Van, Phu, Schuler, Maik

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Recommended criteria for the evaluation of bacterial mutagenicity data (Ames test) von Levy, Dan D., Zeiger, Errol, Escobar, Patricia A., Hakura, Atsushi, van der Leede, Bas-jan M., Kato, Masayuki, Moore, Martha M., Sugiyama, Kei-ichi

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Use of the bacterial reverse mutation assay to predict carcinogenicity of N-nitrosamines von Trejo-Martin, Alejandra, Bercu, Joel P., Thresher, Andrew, Tennant, Rachael E., Thomas, Robert F., Cross, Kevin, Czich, Andreas, Waese, Kerstin, Nicolette, John J., Murray, Joel, Sonders, Paul, Kondratiuk, Alison, Cheung, Jennifer R., Thomas, Dean, Lynch, Anthony, Harvey, James, Glowienke, Susanne, Custer, Laura, Escobar, Patricia A.

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Comprehensive genotoxicity and carcinogenicity assessment of molnupiravir von Escobar, Patricia A, Sobol, Zhanna, Miller, Randy R, Ferry-Martin, Sandrine, Stermer, Angela, Jacob, Binod, Muniappa, Nagaraja, Sanchez, Rosa I, Blanchard, Kerry T, Galijatovic-Idrizbegovic, Alema, Amin, Rupesh P, Troth, Sean P

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A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies von Corton, J Christopher, Mitchell, Constance A, Auerbach, Scott, Bushel, Pierre, Ellinger-Ziegelbauer, Heidrun, Escobar, Patricia A, Froetschl, Roland, Harrill, Alison H, Johnson, Kamin, Klaunig, James E, Pandiri, Arun R, Podtelezhnikov, Alexei A, Rager, Julia E, Tanis, Keith Q, van der Laan, Jan Willem, Vespa, Alisa, Yauk, Carole L, Pettit, Syril D, Sistare, Frank D

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N-nitrosamine impurity risk assessment in pharmaceuticals: Utilizing In vivo mutation relative potency comparison to establish an acceptable intake for NTTP von Powley, Mark W., Sobol, Zhanna, Johnson, George E., Clark, Robert W., Dalby, Stephen M., Ykoruk, Bridget A., Galijatovic-Idrizbegovic, Alema, Mowery, Mark D., Escobar, Patricia A.

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Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology von Lynch, Anthony M, Zanoni, Thalita B, Salk, Jesse J, Martincorena, Inigo, Young, Robert R, Kucab, Jill, Valentine, Charles C, Yauk, Carole, Escobar, Patricia A, Witt, Kristine L, Frötschl, Roland, Reed, Simon H, Ashford, Anne

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Demonstrating laboratory proficiency in bacterial mutagenicity assays for regulatory submission von Levy, Dan D., Hakura, Atsushi, Elespuru, Rosalie K., Escobar, Patricia A., Kato, Masayuki, Lott, Jasmin, Moore, Martha M., Sugiyama, Kei-ichi

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Predictions of genotoxic potential, mode of action, molecular targets, and potency via a tiered multiflow® assay data analysis strategy von Dertinger, Stephen D., Kraynak, Andrew R., Wheeldon, Ryan P., Bernacki, Derek T., Bryce, Steven M., Hall, Nikki, Bemis, Jeffrey C., Galloway, Sheila M., Escobar, Patricia A., Johnson, George E.

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Critical issues with the in vivo comet assay: A report of the comet assay working group in the 6th International Workshop on Genotoxicity Testing (IWGT) von Speit, Günter, Kojima, Hajime, Burlinson, Brian, Collins, Andrew R., Kasper, Peter, Plappert-Helbig, Ulla, Uno, Yoshifumi, Vasquez, Marie, Beevers, Carol, De Boeck, Marlies, Escobar, Patricia A., Kitamoto, Sachiko, Pant, Kamala, Pfuhler, Stefan, Tanaka, Jin, Levy, Dan D.

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Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspective von Reynolds, Vincent L., Butler, Paul, Abernathy, Matthew M., Aschenbrenner, Laura, Best, Derek D., Blank, Jim, Crosby, Meredith, Custer, Laura, Escobar, Patricia A., Kolaja, Kyle, Moggs, Jonathan, Shuey, Dana, Snyder, Chelsea, Van Vleet, Terry, Zhou, Junguo, Hart, Timothy K.

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In Vivo Mutagenicity Testing of Arylboronic Acids and Esters von Masuda‐Herrera, Melisa J., Dobo, Krista L., Kenyon, Michelle O., Kenny, Julia D., Galloway, Sheila M., Escobar, Patricia A., Reddy, M. Vijayaraj, Jolly, Robert A., Trejo‐Martin, Alejandra, Brown, Caren, Mckeon, Marie, Young, Megan, Bruce, Shannon, Pant, Kamala, Dutta, Aparajita, Kulkarni, Rohan, Bercu, Joel P.

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Revisiting the bacterial mutagenicity assays: Report by a workgroup of the International Workshops on Genotoxicity Testing (IWGT) von Schoeny, Rita, Cross, Kevin P., DeMarini, David M., Elespuru, Rosalie, Hakura, Atsushi, Levy, Dan D., Williams, Richard V., Zeiger, Errol, Escobar, Patricia A., Howe, Jonathan R., Kato, Masayuki, Lott, Jasmin, Moore, Martha M., Simon, Stephanie, Stankowski, Leon F., Sugiyama, Kei-ichi, van der Leede, Bas-jan M.

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A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic von Smith, James D., Huang, Zimei, Escobar, Patricia A., Foppiano, Pamela, Maw, Hlaing, Loging, William, Yu, Hongbin, Phillips, Jonathan A., Taub, Mitchell, Ku, Warren W.

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Omics—Current applications in toxicology von Coleman, Matthew A., Escobar, Patricia A., Mahadevan, Brinda

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New and emerging technologies for genetic toxicity testing von Lynch, Anthony M, Sasaki, Jennifer C, Elespuru, Rosalie, Jacobson-Kram, David, Thybaud, Véronique, De Boeck, Marlies, Aardema, Marilyn J, Aubrecht, Jiri, Benz, R. Daniel, Dertinger, Stephen D, Douglas, George R, White, Paul A, Escobar, Patricia A, Fornace, Albert Jr, Honma, Masamitsu, Naven, Russell T, Rusling, James F, Schiestl, Robert H, Walmsley, Richard M, Yamamura, Eiji, van Benthem, Jan, Kim, James H

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Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Gen... von Luijten, Mirjam, van Benthem, Jan, Morita, Takeshi, Corvi, Raffaella, Escobar, Patricia A, Fujita, Yurika, Hemmerich, Jennifer, Honarvar, Naveed, Kirkland, David, Koyama, Naoki, Lovell, David P, Mathea, Miriam, Williams, Andrew, Dertinger, Stephen, Pfuhler, Stefan, Pennings, Jeroen L A

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In vivo Mutagenicity Testing of Arylboronic Acids and Esters (vol 60, pg 766, 2019) von Masuda-Herrera, Melisa J., Dobo, Krista L., Kenyon, Michelle O., Kenny, Julia D., Galloway, Sheila M., Escobar, Patricia A., Reddy, M. Vijayaraj, Jolly, Robert A., Trejo-Martin, Alejandra, Brown, Caren, Mckeon, Marie, Young, Megan, Bruce, Shannon, Pant, Kamala, Dutta, Aparajita, Kulkarni, Rohan, Bercu, Joel P.

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