Lessons in Molecular Recognition:  The Effects of Ligand and Protein Flexibility on Molecular Docking Accuracy von Erickson, Jon A, Jalaie, Mehran, Robertson, Daniel H, Lewis, Richard A, Vieth, Michal

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Lessons in Molecular Recognition. 2. Assessing and Improving Cross-Docking Accuracy von Sutherland, Jeffrey J, Nandigam, Ravi K, Erickson, Jon A, Vieth, Michal

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Preparation and biological evaluation of conformationally constrained BACE1 inhibitors von Winneroski, Leonard L., Schiffler, Matthew A., Erickson, Jon A., May, Patrick C., Monk, Scott A., Timm, David E., Audia, James E., Beck, James P., Boggs, Leonard N., Borders, Anthony R., Boyer, Robert D., Brier, Richard A., Hudziak, Kevin J., Klimkowski, Valentine J., Garcia Losada, Pablo, Mathes, Brian M., Stout, Stephanie L., Watson, Brian M., Mergott, Dustin J.

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Fragment-Based Design of Kinase Inhibitors: A Practical Guide von Erickson, Jon A.

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The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans von May, Patrick C, Willis, Brian A, Lowe, Stephen L, Dean, Robert A, Monk, Scott A, Cocke, Patrick J, Audia, James E, Boggs, Leonard N, Borders, Anthony R, Brier, Richard A, Calligaro, David O, Day, Theresa A, Ereshefsky, Larry, Erickson, Jon A, Gevorkyan, Hykop, Gonzales, Celedon R, James, Douglas E, Jhee, Stanford S, Komjathy, Steven F, Li, Linglin, Lindstrom, Terry D, Mathes, Brian M, Martényi, Ferenc, Sheehan, Scott M, Stout, Stephanie L, Timm, David E, Vaught, Grant M, Watson, Brian M, Winneroski, Leonard L, Yang, Zhixiang, Mergott, Dustin J

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Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor von McKinzie, David L, Winneroski, Leonard L, Green, Steven J, Hembre, Erik J, Erickson, Jon A, Willis, Brian A, Monk, Scott A, Aluise, Christopher D, Baker, Thomas K, Lopez, Jose E, Hendle, Jörg, Beck, James P, Brier, Richard A, Boggs, Leonard N, Borders, Anthony R, Cocke, Patrick J, Garcia-Losada, Pablo, Lowe, Stephen L, Mathes, Brian M, May, Patrick C, Porter, Warren J, Stout, Stephanie L, Timm, David E, Watson, Brian M, Yang, Zhixiang, Mergott, Dustin J

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Idea2Data: Toward a New Paradigm for Drug Discovery von Nicolaou, Christos A, Humblet, Christine, Hu, Hong, Martin, Eva M, Dorsey, Frank C, Castle, Thomas M, Burton, Keith Ian, Hu, Haitao, Hendle, Jorg, Hickey, Michael J, Duerksen, Joel, Wang, Jibo, Erickson, Jon A

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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraints von Winneroski, Leonard L., Erickson, Jon A., Green, Steven J., Lopez, Jose E., Stout, Stephanie L., Porter, Warren J., Timm, David E., Audia, James E., Barberis, Mario, Beck, James P., Boggs, Leonard N., Borders, Anthony R., Boyer, Robert D., Brier, Richard A., Hembre, Erik J., Hendle, Jörg, Garcia-Losada, Pablo, Minguez, Jose Miguel, Mathes, Brian M., May, Patrick C., Monk, Scott A., Rankovic, Zoran, Shi, Yuan, Watson, Brian M., Yang, Zhixiang, Mergott, Dustin J.

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Discovery of (1S,2R,3S,4S,5R,6R)‑2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabo... von Chappell, Mark D, Li, Renhua, Smith, Stephon C, Dressman, Bruce A, Tromiczak, Eric G, Tripp, Allie E, Blanco, Maria-Jesus, Vetman, Tatiana, Quimby, Steven J, Matt, James, Britton, Thomas C, Fivush, Adam M, Schkeryantz, Jeffrey M, Mayhugh, Daniel, Erickson, Jon A, Bures, Mark G, Jaramillo, Carlos, Carpintero, Mercedes, Diego, José Eugenio de, Barberis, Mario, Garcia-Cerrada, Susana, Soriano, José F, Antonysamy, Stephen, Atwell, Shane, MacEwan, Iain, Condon, Bradley, Sougias, Christine, Wang, Jing, Zhang, Aiping, Conners, Kris, Groshong, Chris, Wasserman, Stephen R, Koss, John W, Witkin, Jeffrey M, Li, Xia, Overshiner, Carl, Wafford, Keith A, Seidel, Wesley, Wang, Xu-Shan, Heinz, Beverly A, Swanson, Steven, Catlow, John T, Bedwell, David W, Monn, James A, Mitch, Charles H, Ornstein, Paul L

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Design and synthesis of statine-containing BACE inhibitors von JINGDAN HU, CWI, Cynthia L, MCCARTHY, James R, SMILEY, David L, TIMM, David, ERICKSON, Jon A, MCGEE, James E, YANG, Hsiu-Chiung, MENDEL, David, MAY, Patrick C, SHAPIRO, Mike

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Structure-guided expansion of kinase fragment libraries driven by support vector machine models von Erickson, Jon A., Mader, Mary M., Watson, Ian A., Webster, Yue W., Higgs, Richard E., Bell, Michael A., Vieth, Michal

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Predicting the Accuracy of Ligand Overlay Methods with Random Forest Models von Nandigam, Ravi K, Evans, David A, Erickson, Jon A, Kim, Sangtae, Sutherland, Jeffrey J

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Ecological Economics of Sustainable Watershed Management von Erickson, Jon D, Messner, Frank, Ring, Irene

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Novel Potent 5-HT1F Receptor Agonists:  Structure−Activity Studies of a Series of Substituted N-[3-(1-Methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides von Filla, Sandra A, Mathes, Brian M, Johnson, Kirk W, Phebus, Lee A, Cohen, Marlene L, Nelson, David L, Zgombick, John M, Erickson, Jon A, Schenck, Kathryn W, Wainscott, David B, Branchek, Theresa A, Schaus, John M

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Biochemical and kinetic characterization of BACE1: investigation into the putative species‐specificity for β‐ and β′‐cleavage sites by human and murine BACE1 von Yang, Hsiu‐Chiung, Chai, Xiyun, Mosior, Marian, Kohn, Wayne, Boggs, Leonard N., Erickson, Jon A., McClure, Don B., Yeh, Wu‐Kuang, Zhang, Lianshen, Gonzalez‐DeWhitt, Patricia, Mayer, John P., Martin, Jose Alfredo, Hu, Jingdan, Chen, Shu‐hui, Bueno, Ana Belen, Little, Sheila P., McCarthy, James R., May, Patrick C.

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Homology model directed alignment selection for comparative molecular field analysis: application to photosystem II inhibitors von Jalaie, M, Erickson, J A

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Hacking: The Art of Exploitation von Erickson, Jon

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The Stereochemical Outcome of Electrophilic Addition Reactions on the 5,6-Double Bond in the Spinosyns von De Amicis, Carl V, Graupner, Paul R, Erickson, Jon A, Paschal, Jonathon W, Kirst, Herbert A, Creemer, Lawrence C, Fanwick, Phillip E

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Hydrogen Bond Donor Properties of the Difluoromethyl Group von Erickson, Jon A, McLoughlin, Jim I

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Theoretical Studies of Thermal Syn Elimination Reactions. The Relative Rates of Ethyl Formate, Ethyl Xanthate, and Ethyl Phosphinate Eliminations von Erickson, Jon A, Kahn, Scott D

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