Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria von McGregor, Tracy L, Hunt, Karen A, Yee, Elaine, Mason, Dan, Nioi, Paul, Ticau, Simina, Pelosi, Marissa, Loken, Perry R, Finer, Sarah, Lawlor, Deborah A, Fauman, Eric B, Huang, Qin Qin, Griffiths, Christopher J, MacArthur, Daniel G, Trembath, Richard C, Oglesbee, Devin, Lieske, John C, Erbe, David V, Wright, John, van Heel, David A

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Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface von Schmidt, Michael M., Townson, Sharon A., Andreucci, Amy J., King, Bracken M., Schirmer, Emily B., Murillo, Alec J., Dombrowski, Christian, Tisdale, Alison W., Lowden, Patricia A., Masci, Allyson L., Kovalchin, Joseph T., Erbe, David V., Wittrup, K. Dane, Furfine, Eric S., Barnes, Thomas M.

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Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors:  From the Active Site to the Second Phosphotyrosine Binding Site von Wilson, Douglas P, Wan, Zhao-Kui, Xu, Wei-Xin, Kirincich, Steven J, Follows, Bruce C, Joseph-McCarthy, Diane, Foreman, Kenneth, Moretto, Alessandro, Wu, Junjun, Zhu, Min, Binnun, Eva, Zhang, Yan-Ling, Tam, May, Erbe, David V, Tobin, James, Xu, Xin, Leung, Louis, Shilling, Adam, Tam, Steve Y, Mansour, Tarek S, Lee, Jinbo

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Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial von Frishberg, Yaacov, Deschênes, Georges, Groothoff, Jaap W, Hulton, Sally-Anne, Magen, Daniella, Harambat, Jérôme, Van't Hoff, William G, Lorch, Ulrike, Milliner, Dawn S, Lieske, John C, Haslett, Patrick, Garg, Pushkal P, Vaishnaw, Akshay K, Talamudupula, Sandeep, Lu, Jiandong, Habtemariam, Bahru A, Erbe, David V, McGregor, Tracy L, Cochat, Pierre

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Ertiprotafib Improves Glycemic Control and Lowers Lipids via Multiple Mechanisms von Erbe, David V, Wang, Suyue, Zhang, Yan-Ling, Harding, Kimberly, Kung, Leslie, Tam, May, Stolz, Leslie, Xing, Yuzhe, Furey, Sarah, Qadri, Ariful, Klaman, Lori D, Tobin, James F

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A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia von Camire, Rodney M, Ivanciu, Lacramioara, Toso, Raffaella, Margaritis, Paris, Pavani, Giulia, Kim, Haein, Schlachterman, Alexander, Liu, Jian-Hua, Clerin, Valerie, Pittman, Debra D, Rose-Miranda, Rosalind, Shields, Kathleen M, Erbe, David V, Tobin, James F, Arruda, Valder R

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Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses von Somers, William S, Stamper, Carin C, Zhang, Yan, Tobin, James F, Erbe, David V, Ikemizu, Shinji, Davis, Simon J, Stahl, Mark L, Seehra, Jasbir, Mosyak, Lidia

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Small Molecule Ligands Define a Binding Site on the Immune Regulatory Protein B7.1 von Erbe, David V., Wang, Suyue, Xing, Yuzhe, Tobin, James F.

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Structure-Based Optimization of Protein Tyrosine Phosphatase-1 B Inhibitors: Capturing Interactions with Arginine 24 von Wan, Zhao-Kui, Lee, Jinbo, Hotchandani, Rajeev, Moretto, Alessandro, Binnun, Eva, Wilson, Douglas P., Kirincich, Steve J., Follows, Bruce C., Ipek, Manus, Xu, Weixin, Joseph-McCarthy, Diane, Zhang, Yan-Ling, Tam, May, Erbe, David V., Tobin, James F., Li, Wei, Tam, Steve Y., Mansour, Tarek S., Wu, Junjun

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PPARδ Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities von Perreault, Mylène, Erbe, David V., Tobin, James F.

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Monocyclic thiophenes as protein tyrosine phosphatase 1B inhibitors: Capturing interactions with Asp48 von Wan, Zhao-Kui, Lee, Jinbo, Xu, Weixin, Erbe, David V., Joseph-McCarthy, Diane, Follows, Bruce C., Zhang, Yan-Ling

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PPAR Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities von Perreault, Mylène, Erbe, David V., Tobin, James F.

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An enzyme-linked immunosorbent assay to measure insulin receptor dephosphorylation by PTP1B von Zhang, Yan-Ling, Tam, May, Kirincich, Steve, Wan, Zhao-Kui, Wilson, Doug, Wu, Jun Jun, Lee, Jinbo, Tobin, James F., Erbe, David V.

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Identification of an E-Selectin Region Critical for Carbohydrate Recognition and Cell Adhesion von Erbe, David V., Wolitzky, Barry A., Presta, Leonard G., Norton, Christine R., Ramos, Robert J., Burns, Daniel K., Rumberger, John M., B. N. Narasinga Rao, Foxall, Carrol, Brandley, Brian K., Lasky, Laurence A.

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P- and E-Selectin Use Common Sites for Carbohydrate Ligand Recognition and Cell Adhesion von Erbe, David V., Watson, Susan R., Presta, Leonard G., Wolitzky, Barry A., Foxall, Carroll, Brandley, Brian K., Lasky, Laurence A.

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Activation of PPARγ by Sartans von Erbe, David V., Gartrell, Katherine, Will, Sarah, Perreault, Mylene, Wang, Suyue, Tobin, James F.

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Molecular activation of PPARγ by angiotensin II type 1-receptor antagonists von Erbe, David V., Gartrell, Katherine, Zhang, Yan-Ling, Suri, Vipin, Kirincich, Steven J., Will, Sarah, Perreault, Mylene, Wang, Suyue, Tobin, James F.

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PTP1b: A Promising and Challenging Target for Metabolic Disease von ., Yan-ling Zhang, ., James F. Tobin, ., David V. Erbe

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Antibodies to B7.1 define the GFCC′C″ face of the N-terminal domain as critical for co-stimulatory interactions von Wang, Suyue, Veldman, Geertruida M, Stahl, Mark, Xing, Yuzhe, Tobin, James F, Erbe, David V

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correction: Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses von Stamper, Carin C, Zhang, Yan, Tobin, James F, Erbe, David V, Ikemizu, Shinji, Davis, Simon J, Stahl, Mark L, Seehra, Jasbir, Somers, William S, Mosyak, Lidia

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