Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance von Bagchi, Sreya, Yuan, Robert, Engleman, Edgar G

Volltext

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization von Alcántara-Hernández, Marcela, Leylek, Rebecca, Wagar, Lisa E., Engleman, Edgar G., Keler, Tibor, Marinkovich, M. Peter, Davis, Mark M., Nolan, Garry P., Idoyaga, Juliana

Volltext

Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions von Filatenkov, Alexander, Baker, Jeanette, Mueller, Antonia M S, Kenkel, Justin, Ahn, G-One, Dutt, Suparna, Zhang, Nigel, Kohrt, Holbrook, Jensen, Kent, Dejbakhsh-Jones, Sussan, Shizuru, Judith A, Negrin, Robert N, Engleman, Edgar G, Strober, Samuel

Volltext

Mechanical Stiffness Controls Dendritic Cell Metabolism and Function von Chakraborty, Mainak, Chu, Kevin, Shrestha, Annie, Revelo, Xavier S., Zhang, Xiangyue, Gold, Matthew J., Khan, Saad, Lee, Megan, Huang, Camille, Akbari, Masoud, Barrow, Fanta, Chan, Yi Tao, Lei, Helena, Kotoulas, Nicholas K., Jovel, Juan, Pastrello, Chiara, Kotlyar, Max, Goh, Cynthia, Michelakis, Evangelos, Clemente-Casares, Xavier, Ohashi, Pamela S., Engleman, Edgar G., Winer, Shawn, Jurisica, Igor, Tsai, Sue, Winer, Daniel A.

Volltext

An interactive reference framework for modeling a dynamic immune system von Spitzer, Matthew H., Gherardini, Pier Federico, Fragiadakis, Gabriela K., Bhattacharya, Nupur, Yuan, Robert T., Hotson, Andrew N., Finck, Rachel, Carmi, Yaron, Zunder, Eli R., Fantl, Wendy J., Bendall, Sean C., Engleman, Edgar G., Nolan, Garry P.

Volltext

Regulation of Obesity-Related Insulin Resistance with Gut Anti-inflammatory Agents von Luck, Helen, Tsai, Sue, Chung, Jason, Clemente-Casares, Xavier, Ghazarian, Magar, Revelo, Xavier S., Lei, Helena, Luk, Cynthia T., Shi, Sally Yu, Surendra, Anuradha, Copeland, Julia K., Ahn, Jennifer, Prescott, David, Rasmussen, Brittany A., Chng, Melissa Hui Yen, Engleman, Edgar G., Girardin, Stephen E., Lam, Tony K.T., Croitoru, Kenneth, Dunn, Shannon, Philpott, Dana J., Guttman, David S., Woo, Minna, Winer, Shawn, Winer, Daniel A.

Volltext

Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8+ T Cell-Mediated Immunity in Colorectal Cancer von Bhattacharya, Nupur, Yuan, Robert, Prestwood, Tyler R., Penny, Hweixian Leong, DiMaio, Michael A., Reticker-Flynn, Nathan E., Krois, Charles R., Kenkel, Justin A., Pham, Tho D., Carmi, Yaron, Tolentino, Lorna, Choi, Okmi, Hulett, Reyna, Wang, Jinshan, Winer, Daniel A., Napoli, Joseph L., Engleman, Edgar G.

Volltext

An Immunosuppressive Dendritic Cell Subset Accumulates at Secondary Sites and Promotes Metastasis in Pancreatic Cancer von Kenkel, Justin A, Tseng, William W, Davidson, Matthew G, Tolentino, Lorna L, Choi, Okmi, Bhattacharya, Nupur, Seeley, E Scott, Winer, Daniel A, Reticker-Flynn, Nathan E, Engleman, Edgar G

Volltext

B-1a lymphocytes attenuate insulin resistance von Shen, Lei, Chng, Melissa Hui Yen, Alonso, Michael N, Yuan, Robert, Winer, Daniel A, Engleman, Edgar G

Volltext

Tolerance and Chimerism after Renal and Hematopoietic-Cell Transplantation von Scandling, John D, Busque, Stephan, Dejbakhsh-Jones, Sussan, Benike, Claudia, Millan, Maria T, Shizuru, Judith A, Hoppe, Richard T, Lowsky, Robert, Engleman, Edgar G, Strober, Samuel

Volltext

Tolerogenic interactions between CD8+ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts von Hongo, David, Tang, Xiaobin, Zhang, Xiangyue, Engleman, Edgar G., Strober, Samuel

Volltext

Cancer systems immunology von Reticker-Flynn, Nathan E, Engleman, Edgar G

Volltext

Brain profiling in murine colitis and human epilepsy reveals neutrophils and TNFα as mediators of neuronal hyperexcitability von Barnes, Sarah E, Zera, Kristy A, Ivison, Geoffrey T, Buckwalter, Marion S, Engleman, Edgar G

Volltext

Adipose tissue macrophages impair preadipocyte differentiation in humans von Liu, Li Fen, Craig, Colleen M, Tolentino, Lorna L, Choi, Okmi, Morton, John, Rivas, Homero, Cushman, Samuel W, Engleman, Edgar G, McLaughlin, Tracey

Volltext

Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function von Hongo, David, Zheng, Pingping, Dutt, Suparna, Pawar, Rahul D, Meyer, Everett, Engleman, Edgar G, Strober, Samuel

Volltext

Dendritic Cells in Cancer Immunotherapy von Fong, Lawrence, Engleman, Edgar G

Volltext

Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis von Söderström, Kalle, Stein, Emily, Colmenero, Paula, Purath, Ulrich, Müller-Ladner, Ulf, de Matos, Cristina Teixeira, Tarner, Ingo H., Robinson, William H., Engleman, Edgar G., Cantor, Harvey

Volltext

Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency von Moraga, Ignacio, Richter, David, Wilmes, Stephan, Winkelmann, Hauke, Jude, Kevin, Thomas, Christoph, Suhoski, Megan M, Engleman, Edgar G, Piehler, Jacob, Garcia, K Christopher

Volltext

Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer von Yuan, Robert, Bhattacharya, Nupur, Kenkel, Justin A, Shen, Jeanne, DiMaio, Michael A, Bagchi, Sreya, Prestwood, Tyler R, Habtezion, Aida, Engleman, Edgar G

Volltext

Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma von Penny, Hweixian Leong, Sieow, Je Lin, Gun, Sin Yee, Lau, Mai Chan, Lee, Bernett, Tan, Jasmine, Phua, Cindy, Toh, Florida, Nga, Yvonne, Yeap, Wei Hseun, Janela, Baptiste, Kumar, Dilip, Chen, Hao, Yeong, Joe, Kenkel, Justin A, Pang, Angela, Lim, Diana, Toh, Han Chong, Hon, Tony Lim Kiat, Johnson, Christopher I, Khameneh, Hanif Javanmard, Mortellaro, Alessandra, Engleman, Edgar G, Rotzschke, Olaf, Ginhoux, Florent, Abastado, Jean-Pierre, Chen, Jinmiao, Wong, Siew Cheng

Volltext