Gold-Catalyzed Cycloisomerization of N-Propargylindole-2-carboxamides: Application toward the Synthesis of Lavendamycin Analogues von England, Dylan B, Padwa, Albert

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Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer von Langston, Steven P, Grossman, Stephen, England, Dylan, Afroze, Roushan, Bence, Neil, Bowman, Douglas, Bump, Nancy, Chau, Ryan, Chuang, Bei-Ching, Claiborne, Christopher, Cohen, Larry, Connolly, Kelly, Duffey, Matthew, Durvasula, Nitya, Freeze, Scott, Gallery, Melissa, Galvin, Katherine, Gaulin, Jeffrey, Gershman, Rachel, Greenspan, Paul, Grieves, Jessica, Guo, Jianping, Gulavita, Nanda, Hailu, Shumet, He, Xingyue, Hoar, Kara, Hu, Yongbo, Hu, Zhigen, Ito, Mitsuhiro, Kim, Mi-Sook, Lane, Scott Weston, Lok, David, Lublinsky, Anya, Mallender, William, McIntyre, Charles, Minissale, James, Mizutani, Hirotake, Mizutani, Miho, Molchinova, Nina, Ono, Koji, Patil, Ashok, Qian, Mark, Riceberg, Jessica, Shindi, Vaishali, Sintchak, Michael D, Song, Keli, Soucy, Teresa, Wang, Yana, Xu, He, Yang, Xiaofeng, Zawadzka, Agatha, Zhang, Ji, Pulukuri, Sai M

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General Access to the Vinca and Tacaman Alkaloids Using a Rh(II)-Catalyzed Cyclization/Cycloaddition Cascade von England, Dylan B, Padwa, Albert

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Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors von Huang, Shih-Chung, Adhikari, Sharmila, Brownell, James E., Calderwood, Emily F., Chouitar, Jouhara, D'Amore, Natalie Roy, England, Dylan B., Foley, Klaudia, Harrison, Sean J., LeRoy, Patrick J., Lok, David, Lublinsky, Anna, Ma, Li-Ting, Menon, Saurabh, Yang, Yu, Zhang, Ji, Gould, Alexandra E.

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Substitution and Cyclization Reactions Involving the Quasi-Antiaromatic 2H-Indol-2-one Ring System von England, Dylan B, Merey, Gokce, Padwa, Albert

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Synthesis of (±)-3H-Epivincamine via a Rh(II)-Triggered Cyclization/Cycloaddition Cascade von England, Dylan B, Padwa, Albert

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Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform von Blackburn, Christopher, Barrett, Cynthia, Brunson, Mable, Chin, Janice, England, Dylan, Garcia, Kris, Gigstad, Kenneth, Gould, Alexandra, Gutierrez, Juan, Hoar, Kara, Rowland, R. Scott, Tsu, Christopher, Ringeling, John, Wager, Krista, Xu, He

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The rhodium(II) carbenoid cyclization–cycloaddition cascade of α-diazo dihydroindolinones for the synthesis of novel azapolycyclic ring systems von England, Dylan B., Eagan, James M., Merey, Gokce, Anac, Olcay, Padwa, Albert

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Cyclopentannulation of 3-Alkylindoles:  A Synthesis of a Tetracyclic Subunit of the Kopsane Alkaloids von England, Dylan B, Kuss, Timothy D. O, Keddy, Ryan G, Kerr, Michael A

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Optimization of tetrahydronaphthalene inhibitors of Raf with selectivity over hERG von Huang, Shih-Chung, Adhikari, Sharmila, Afroze, Roushan, Brewer, Katherine, Calderwood, Emily F., Chouitar, Jouhara, England, Dylan B., Fisher, Craig, Galvin, Katherine M., Gaulin, Jeffery, Greenspan, Paul D., Harrison, Sean J., Kim, Mi-Sook, Langston, Steven P., Ma, Li-Ting, Menon, Saurabh, Mizutani, Hirotake, Rezaei, Mansoureh, Smith, Michael D., Zhang, Dong Mei, Gould, Alexandra E.

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Synthesis and Cross-Coupling Reactions of Substituted 5-Triflyloxyindoles von England, Dylan B, Kerr, Michael A

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Design and Optimization of Potent and Orally Bioavailable Tetrahydronaphthalene Raf Inhibitors von Gould, Alexandra E, Adams, Ruth, Adhikari, Sharmila, Aertgeerts, Kathleen, Afroze, Roushan, Blackburn, Christopher, Calderwood, Emily F, Chau, Ryan, Chouitar, Jouhara, Duffey, Matthew O, England, Dylan B, Farrer, Cheryl, Forsyth, Nancy, Garcia, Khristofer, Gaulin, Jeffery, Greenspan, Paul D, Guo, Ribo, Harrison, Sean J, Huang, Shih-Chung, Iartchouk, Natalia, Janowick, Dave, Kim, Mi-Sook, Kulkarni, Bheemashankar, Langston, Steven P, Liu, Jane X, Ma, Li-Ting, Menon, Saurabh, Mizutani, Hirotake, Paske, Erin, Renou, Christelle C, Rezaei, Mansoureh, Rowland, R. Scott, Sintchak, Michael D, Smith, Michael D, Stroud, Stephen G, Tregay, Ming, Tian, Yuan, Veiby, Ole P, Vos, Tricia J, Vyskocil, Stepan, Williams, Juliet, Xu, Tianlin, Yang, Johnny J, Yano, Jason, Zeng, Hongbo, Zhang, Dong Mei, Zhang, Qin, Galvin, Katherine M

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Synthesis of (±)-3H-Epivincamine via a Rh(II)-Triggered Cyclization/Cycloaddition Cascade von England, Dylan B, Padwa, Albert

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Synthesis of the Western Half of the Lolicines and Lolitrems von England, Dylan B, Magolan, Jakob, Kerr, Michael A

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Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor von He, Xingyue, Riceberg, Jessica, Soucy, Teresa, Koenig, Erik, Minissale, James, Gallery, Melissa, Bernard, Hugues, Yang, Xiaofeng, Liao, Hua, Rabino, Claudia, Shah, Pooja, Xega, Kristina, Yan, Zhong-hua, Sintchak, Mike, Bradley, John, Xu, He, Duffey, Matt, England, Dylan, Mizutani, Hirotake, Hu, Zhigen, Guo, Jianping, Chau, Ryan, Dick, Lawrence R, Brownell, James E, Newcomb, John, Langston, Steve, Lightcap, Eric S, Bence, Neil, Pulukuri, Sai M

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The Diels−Alder Reactions of Quinone Imine Ketals:  A Versatile Synthesis of Highly Substituted 5-Methoxyindoles von Banfield, Scott C, England, Dylan B, Kerr, Michael A

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Synthesis of substituted β-carbolines via gold(III)-catalyzed cycloisomerization of N-propargylamides von Verniest, Guido, England, Dylan, De Kimpe, Norbert, Padwa, Albert

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Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route von Vyskocil, Stepan, Cardin, David, Ciavarri, Jeffrey, Conlon, Joe, Cullis, Courtney, England, Dylan, Gershman, Rachel, Gigstad, Kenneth, Gipson, Krista, Gould, Alexandra, Greenspan, Paul, Griffin, Robert, Gulavita, Nanda, Harrison, Sean, Hu, Zhigen, Hu, Yongbo, Hata, Akito, Huang, Jian, Huang, Shih-Chung, Janowick, Dave, Jones, Matthew, Kolev, Vihren, Langston, Steven P, Lee, Hong Myung, Li, Gang, Lok, David, Ma, Liting, Mai, Doanh, Malley, Jenna, Matsuda, Atsushi, Mizutani, Hirotake, Mizutani, Miho, Molchanova, Nina, Nunes, Elise, Pusalkar, Sandeep, Renou, Christelle, Rowland, Scott, Sato, Yosuke, Shaw, Michael, Shen, Luhua, Shi, Zhan, Skene, Robert, Soucy, Francois, Stroud, Steve, Xu, He, Xu, Tianlin, Abu-Yousif, Adnan O, Zhang, Ji

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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo von Xie, Stanley C, Tai, Chia-Wei, Morton, Craig J, Ma, Liting, Huang, Shih-Chung, Wittlin, Sergio, Du, Yawei, Hu, Yongbo, Dogovski, Con, Salimimarand, Mina, Griffin, Robert, England, Dylan, de la Cruz, Elisa, Deni, Ioanna, Yeo, Tomas, Burkhard, Anna Y, Striepen, Josefine, Schindler, Kyra A, Crespo, Benigno, Gamo, Francisco J, Khandokar, Yogesh, Hutton, Craig A, Rabie, Tayla, Birkholtz, Lyn-Marié, Famodimu, Mufuliat T, Delves, Michael J, Bolsher, Judith, Koolen, Karin M J, van der Laak, Rianne, Aguiar, Anna C C, Pereira, Dhelio B, Guido, Rafael V C, Creek, Darren J, Fidock, David A, Dick, Lawrence R, Brand, Stephen L, Gould, Alexandra E, Langston, Steven, Griffin, Michael D W, Tilley, Leann

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Abstract 1147: Probing the roles of SUMOylation in cancer cell biology using a selective SUMO activating enzyme inhibitor von Pulukuri, Sai M, He, Xingyue, Grossman, Stephen, Riceberg, Jessica, Koenig, Erik, Soucy, Teresa, Song, Keli, Kreshock, Anna, England, Dylan, Mizutani, Hirotake, Dick, Larry, Brownell, James, Newcomb, John, Langston, Steve, Lightcap, Eric, Galvin, Katherine

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