ERBB Receptors: From Oncogene Discovery to Basic Science to Mechanism-Based Cancer Therapeutics von Arteaga, Carlos L., Engelman, Jeffrey A.

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Transformation from non-small-cell lung cancer to small-cell lung cancer: molecular drivers and cells of origin von Oser, Matthew G, MD, Niederst, Matthew J, PhD, Sequist, Lecia V, MD, Engelman, Jeffrey A, Dr

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ALK in Lung Cancer: Past, Present, and Future von Shaw, Alice T, Engelman, Jeffrey A

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The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics von Hata, Aaron N, Engelman, Jeffrey A, Faber, Anthony C

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The PI3K Pathway As Drug Target in Human Cancer von COURTNEY, Kevin D, CORCORAN, Ryan B, ENGELMAN, Jeffrey A

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Bypass mechanisms of resistance to receptor tyrosine kinase inhibition in lung cancer von Niederst, Matthew J, Engelman, Jeffrey A

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Anchored multiplex PCR for targeted next-generation sequencing von Zheng, Zongli, Liebers, Matthew, Zhelyazkova, Boryana, Cao, Yi, Panditi, Divya, Lynch, Kerry D, Chen, Juxiang, Robinson, Hayley E, Shim, Hyo Sup, Chmielecki, Juliann, Pao, William, Engelman, Jeffrey A, Iafrate, A John, Le, Long Phi

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CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors von Vora, Sadhna R., Juric, Dejan, Kim, Nayoon, Mino-Kenudson, Mari, Huynh, Tiffany, Costa, Carlotta, Lockerman, Elizabeth L., Pollack, Sarah F., Liu, Manway, Li, Xiaoyan, Lehar, Joseph, Wiesmann, Marion, Wartmann, Markus, Chen, Yan, Cao, Z. Alexander, Pinzon-Ortiz, Maria, Kim, Sunkyu, Schlegel, Robert, Huang, Alan, Engelman, Jeffrey A.

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Targeting the PI3K signaling pathway in cancer von Wong, Kwok-Kin, Engelman, Jeffrey A, Cantley, Lewis C

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The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism von Engelman, Jeffrey A., Luo, Ji, Cantley, Lewis C.

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Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia von Orlando, Elena J., Han, Xia, Tribouley, Catherine, Wood, Patricia A., Leary, Rebecca J., Riester, Markus, Levine, John E., Qayed, Muna, Grupp, Stephan A., Boyer, Michael, De Moerloose, Barbara, Nemecek, Eneida R., Bittencourt, Henrique, Hiramatsu, Hidefumi, Buechner, Jochen, Davies, Stella M., Verneris, Michael R., Nguyen, Kevin, Brogdon, Jennifer L., Bitter, Hans, Morrissey, Michael, Pierog, Piotr, Pantano, Serafino, Engelman, Jeffrey A., Winckler, Wendy

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Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer von Engelman, Jeffrey A., Jänne, Pasi A.

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A combinatorial strategy for treating KRAS-mutant lung cancer von Manchado, Eusebio, Weissmueller, Susann, Morris, John P., Chen, Chi-Chao, Wullenkord, Ramona, Lujambio, Amaia, de Stanchina, Elisa, Poirier, John T., Gainor, Justin F., Corcoran, Ryan B., Engelman, Jeffrey A., Rudin, Charles M., Rosen, Neal, Lowe, Scott W.

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Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer von Yoda, Satoshi, Lin, Jessica J, Lawrence, Michael S, Burke, Benjamin J, Friboulet, Luc, Langenbucher, Adam, Dardaei, Leila, Prutisto-Chang, Kylie, Dagogo-Jack, Ibiayi, Timofeevski, Sergei, Hubbeling, Harper, Gainor, Justin F, Ferris, Lorin A, Riley, Amanda K, Kattermann, Krystina E, Timonina, Daria, Heist, Rebecca S, Iafrate, A John, Benes, Cyril H, Lennerz, Jochen K, Mino-Kenudson, Mari, Engelman, Jeffrey A, Johnson, Ted W, Hata, Aaron N, Shaw, Alice T

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints von Koyama, Shohei, Akbay, Esra A., Li, Yvonne Y., Herter-Sprie, Grit S., Buczkowski, Kevin A., Richards, William G., Gandhi, Leena, Redig, Amanda J., Rodig, Scott J., Asahina, Hajime, Jones, Robert E., Kulkarni, Meghana M., Kuraguchi, Mari, Palakurthi, Sangeetha, Fecci, Peter E., Johnson, Bruce E., Janne, Pasi A., Engelman, Jeffrey A., Gangadharan, Sidharta P., Costa, Daniel B., Freeman, Gordon J., Bueno, Raphael, Hodi, F. Stephen, Dranoff, Glenn, Wong, Kwok-Kin, Hammerman, Peter S.

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Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms von Hu, Haichuan, Piotrowska, Zofia, Hare, Patricia J., Chen, Huidong, Mulvey, Hillary E., Mayfield, Aislinn, Noeen, Sundus, Kattermann, Krystina, Greenberg, Max, Williams, August, Riley, Amanda K., Wilson, Jarad J., Mao, Ying-Qing, Huang, Ruo-Pan, Banwait, Mandeep K., Ho, Jeffrey, Crowther, Giovanna S., Hariri, Lida P., Heist, Rebecca S., Kodack, David P., Pinello, Luca, Shaw, Alice T., Mino-Kenudson, Mari, Hata, Aaron N., Sequist, Lecia V., Benes, Cyril H., Niederst, Matthew J., Engelman, Jeffrey A.

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Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models von Corcoran, Ryan B., Cheng, Katherine A., Hata, Aaron N., Faber, Anthony C., Ebi, Hiromichi, Coffee, Erin M., Greninger, Patricia, Brown, Ronald D., Godfrey, Jason T., Cohoon, Travis J., Song, Youngchul, Lifshits, Eugene, Hung, Kenneth E., Shioda, Toshi, Dias-Santagata, Dora, Singh, Anurag, Settleman, Jeffrey, Benes, Cyril H., Mino-Kenudson, Mari, Wong, Kwok-Kin, Engelman, Jeffrey A.

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ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers von BERGETHON, Kristin, SHAW, Alice T, MARK, Eugene J, BATTEN, Julie M, HAIQUAN CHEN, WILNER, Keith D, KWAK, Eunice L, CLARK, Jeffrey W, CARBONE, David P, HONGBIN JI, ENGELMAN, Jeffrey A, MINO-KENUDSON, Mari, IGNATIUS OU, Sai-Hong, PAO, William, IAFRATE, A. John, KATAYAMA, Ryohei, LOVLY, Christine M, MCDONALD, Nerina T, MASSION, Pierre P, SIWAK-TAPP, Christina, GONZALEZ, Adriana, RONG FANG

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Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer von Raoof, Sana, Mulford, Iain J., Frisco-Cabanos, Heidie, Nangia, Varuna, Timonina, Daria, Labrot, Emma, Hafeez, Nafeeza, Bilton, Samantha J., Drier, Yotam, Ji, Fei, Greenberg, Max, Williams, August, Kattermann, Krystina, Damon, Leah, Sovath, Sosathya, Rakiec, Daniel P., Korn, Joshua M., Ruddy, David A., Benes, Cyril H., Hammerman, Peter S., Piotrowska, Zofia, Sequist, Lecia V., Niederst, Matthew J., Barretina, Jordi, Engelman, Jeffrey A., Hata, Aaron N.

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TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts von Grauel, Angelo L., Nguyen, Beverly, Ruddy, David, Laszewski, Tyler, Schwartz, Stephanie, Chang, Jonathan, Chen, Julie, Piquet, Michelle, Pelletier, Marc, Yan, Zheng, Kirkpatrick, Nathaniel D., Wu, Jincheng, deWeck, Antoine, Riester, Markus, Hims, Matt, Geyer, Felipe Correa, Wagner, Joel, MacIsaac, Kenzie, Deeds, James, Diwanji, Rohan, Jayaraman, Pushpa, Yu, Yenyen, Simmons, Quincey, Weng, Shaobu, Raza, Alina, Minie, Brian, Dostalek, Mirek, Chikkegowda, Pavitra, Ruda, Vera, Iartchouk, Oleg, Chen, Naiyan, Thierry, Raphael, Zhou, Joseph, Pruteanu-Malinici, Iulian, Fabre, Claire, Engelman, Jeffrey A., Dranoff, Glenn, Cremasco, Viviana

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