Single-Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations von Kalluri, Aditya S, Vellarikkal, Shamsudheen K, Edelman, Elazer R, Nguyen, Lan, Subramanian, Ayshwarya, Ellinor, Patrick T, Regev, Aviv, Kathiresan, Sekar, Gupta, Rajat M

Volltext

Emerging Directions in the Genetics of Atrial Fibrillation von Tucker, Nathan R, Ellinor, Patrick T

Volltext

Transcriptional and Cellular Diversity of the Human Heart von Tucker, Nathan R., Chaffin, Mark, Fleming, Stephen J., Hall, Amelia W., Parsons, Victoria A., Bedi, Kenneth C., Akkad, Amer-Denis, Herndon, Caroline N., Arduini, Alessandro, Papangeli, Irinna, Roselli, Carolina, Aguet, François, Choi, Seung Hoan, Ardlie, Kristin G., Babadi, Mehrtash, Margulies, Kenneth B., Stegmann, Christian M., Ellinor, Patrick T.

Volltext

ECG-Based Deep Learning and Clinical Risk Factors to Predict Atrial Fibrillation von Khurshid, Shaan, Friedman, Samuel, Reeder, Christopher, Di Achille, Paolo, Diamant, Nathaniel, Singh, Pulkit, Harrington, Lia X., Wang, Xin, Al-Alusi, Mostafa A., Sarma, Gopal, Foulkes, Andrea S., Ellinor, Patrick T., Anderson, Christopher D., Ho, Jennifer E., Philippakis, Anthony A., Batra, Puneet, Lubitz, Steven A.

Volltext

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions von Fahed, Akl C., Wang, Minxian, Homburger, Julian R., Patel, Aniruddh P., Bick, Alexander G., Neben, Cynthia L., Lai, Carmen, Brockman, Deanna, Philippakis, Anthony, Ellinor, Patrick T., Cassa, Christopher A., Lebo, Matthew, Ng, Kenney, Lander, Eric S., Zhou, Alicia Y., Kathiresan, Sekar, Khera, Amit V.

Volltext

Macrophages Facilitate Electrical Conduction in the Heart von Hulsmans, Maarten, Clauss, Sebastian, Xiao, Ling, Aguirre, Aaron D., King, Kevin R., Hanley, Alan, Hucker, William J., Wülfers, Eike M., Seemann, Gunnar, Courties, Gabriel, Iwamoto, Yoshiko, Sun, Yuan, Savol, Andrej J., Sager, Hendrik B., Lavine, Kory J., Fishbein, Gregory A., Capen, Diane E., Da Silva, Nicolas, Miquerol, Lucile, Wakimoto, Hiroko, Seidman, Christine E., Seidman, Jonathan G., Sadreyev, Ruslan I., Naxerova, Kamila, Mitchell, Richard N., Brown, Dennis, Libby, Peter, Weissleder, Ralph, Swirski, Filip K., Kohl, Peter, Vinegoni, Claudio, Milan, David J., Ellinor, Patrick T., Nahrendorf, Matthias

Volltext

2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary von Calkins, Hugh, Hindricks, Gerhard, Cappato, Riccardo, Kim, Young-Hoon, Saad, Eduardo B., Aguinaga, Luis, Akar, Joseph G., Badhwar, Vinay, Brugada, Josep, Camm, John, Chen, Peng-Sheng, Chen, Shih-Ann, Chung, Mina K., Nielsen, Jens Cosedis, Curtis, Anne B., Davies, D. Wyn, Day, John D., d’Avila, André, de Groot, N.M.S. (Natasja), Di Biase, Luigi, Duytschaever, Mattias, Edgerton, James R., Ellenbogen, Kenneth A., Ellinor, Patrick T., Ernst, Sabine, Fenelon, Guilherme, Gerstenfeld, Edward P., Haines, David E., Haissaguerre, Michel, Helm, Robert H., Hylek, Elaine, Jackman, Warren M., Jalife, Jose, Kalman, Jonathan M., Kautzner, Josef, Kottkamp, Hans, Kuck, Karl Heinz, Kumagai, Koichiro, Lee, Richard, Lewalter, Thorsten, Lindsay, Bruce D., Macle, Laurent, Mansour, Moussa, Marchlinski, Francis E., Michaud, Gregory F., Nakagawa, Hiroshi, Natale, Andrea, Nattel, Stanley, Okumura, Ken, Packer, Douglas, Pokushalov, Evgeny, Reynolds, Matthew R., Sanders, Prashanthan, Scanavacca, Mauricio, Schilling, Richard, Tondo, Claudio, Tsao, Hsuan-Ming, Verma, Atul, Wilber, David J., Yamane, Teiichi

Volltext

Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study von Staerk, Laila, Wang, Biqi, Preis, Sarah R, Larson, Martin G, Lubitz, Steven A, Ellinor, Patrick T, McManus, David D, Ko, Darae, Weng, Lu-Chen, Lunetta, Kathryn L, Frost, Lars, Benjamin, Emelia J, Trinquart, Ludovic

Volltext

Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy von Chaffin, Mark, Papangeli, Irinna, Simonson, Bridget, Akkad, Amer-Denis, Hill, Matthew C., Arduini, Alessandro, Fleming, Stephen J., Melanson, Michelle, Hayat, Sikander, Kost-Alimova, Maria, Atwa, Ondine, Ye, Jiangchuan, Bedi, Kenneth C., Nahrendorf, Matthias, Kaushik, Virendar K., Stegmann, Christian M., Margulies, Kenneth B., Tucker, Nathan R., Ellinor, Patrick T.

Volltext

50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study von Schnabel, Renate B, Dr, Yin, Xiaoyan, PhD, Gona, Philimon, Phd, Larson, Martin G, ScD, Beiser, Alexa S, PhD, McManus, David D, MD, Newton-Cheh, Christopher, MD, Lubitz, Steven A, MD, Magnani, Jared W, MD, Ellinor, Patrick T, MD, Seshadri, Sudha, MD, Wolf, Philip A, MD, Vasan, Ramachandran S, Prof, Benjamin, Emelia J, Prof, Levy, Daniel, Prof

Volltext

Frequency of Cardiac Rhythm Abnormalities in a Half Million Adults von Khurshid, Shaan, Choi, Seung Hoan, Weng, Lu-Chen, Wang, Elizabeth Y, Trinquart, Ludovic, Benjamin, Emelia J, Ellinor, Patrick T, Lubitz, Steven A

Volltext

Transcriptome variation in human tissues revealed by long-read sequencing von Glinos, Dafni A., Garborcauskas, Garrett, Hoffman, Paul, Ehsan, Nava, Jiang, Lihua, Gokden, Alper, Dai, Xiaoguang, Aguet, François, Brown, Kathleen L., Garimella, Kiran, Bowers, Tera, Costello, Maura, Ardlie, Kristin, Jian, Ruiqi, Tucker, Nathan R., Ellinor, Patrick T., Harrington, Eoghan D., Tang, Hua, Snyder, Michael, Juul, Sissel, Mohammadi, Pejman, MacArthur, Daniel G., Lappalainen, Tuuli, Cummings, Beryl B.

Volltext

Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation von Weng, Lu-Chen, Preis, Sarah R, Hulme, Olivia L, Larson, Martin G, Choi, Seung Hoan, Wang, Biqi, Trinquart, Ludovic, McManus, David D, Staerk, Laila, Lin, Honghuang, Lunetta, Kathryn L, Ellinor, Patrick T, Benjamin, Emelia J, Lubitz, Steven A

Volltext

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy von Pirruccello, James P., Bick, Alexander, Wang, Minxian, Chaffin, Mark, Friedman, Samuel, Yao, Jie, Guo, Xiuqing, Venkatesh, Bharath Ambale, Taylor, Kent D., Post, Wendy S., Rich, Stephen, Lima, Joao A. C., Rotter, Jerome I., Philippakis, Anthony, Lubitz, Steven A., Ellinor, Patrick T., Khera, Amit V., Kathiresan, Sekar, Aragam, Krishna G.

Volltext

Genetics of atrial fibrillation: from families to genomes von Christophersen, Ingrid E, Ellinor, Patrick T

Volltext

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank von Jurgens, Sean J., Choi, Seung Hoan, Morrill, Valerie N., Chaffin, Mark, Pirruccello, James P., Halford, Jennifer L., Weng, Lu-Chen, Nauffal, Victor, Roselli, Carolina, Hall, Amelia W., Oetjens, Matthew T., Lagerman, Braxton, vanMaanen, David P., Aragam, Krishna G., Lunetta, Kathryn L., Haggerty, Christopher M., Lubitz, Steven A., Ellinor, Patrick T.

Volltext

MMCT-Loop: a mix model-based pipeline for calling targeted 3D chromatin loops von Tang, Li, Liao, Jiaqi, Hill, Matthew C, Hu, Jiaxin, Zhao, Yichao, Ellinor, Patrick T, Li, Min

Volltext

Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots von Agrawal, Saaket, Wang, Minxian, Klarqvist, Marcus D. R., Smith, Kirk, Shin, Joseph, Dashti, Hesam, Diamant, Nathaniel, Choi, Seung Hoan, Jurgens, Sean J., Ellinor, Patrick T., Philippakis, Anthony, Claussnitzer, Melina, Ng, Kenney, Udler, Miriam S., Batra, Puneet, Khera, Amit V.

Volltext

Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation von Choi, Seung Hoan, Weng, Lu-Chen, Roselli, Carolina, Lin, Honghuang, Haggerty, Christopher M, Shoemaker, M. Benjamin, Barnard, John, Arking, Dan E, Chasman, Daniel I, Albert, Christine M, Chaffin, Mark, Tucker, Nathan R, Smith, Jonathan D, Gupta, Namrata, Gabriel, Stacey, Margolin, Lauren, Shea, Marisa A, Shaffer, Christian M, Yoneda, Zachary T, Boerwinkle, Eric, Smith, Nicholas L, Silverman, Edwin K, Redline, Susan, Vasan, Ramachandran S, Burchard, Esteban G, Gogarten, Stephanie M, Laurie, Cecelia, Blackwell, Thomas W, Abecasis, Gonçalo, Carey, David J, Fornwalt, Brandon K, Smelser, Diane T, Baras, Aris, Dewey, Frederick E, Jaquish, Cashell E, Papanicolaou, George J, Sotoodehnia, Nona, Van Wagoner, David R, Psaty, Bruce M, Kathiresan, Sekar, Darbar, Dawood, Alonso, Alvaro, Heckbert, Susan R, Chung, Mina K, Roden, Dan M, Benjamin, Emelia J, Murray, Michael F, Lunetta, Kathryn L, Lubitz, Steven A, Ellinor, Patrick T

Volltext

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci von Lessard, Samuel, Francioli, Laurent, Alfoldi, Jessica, Tardif, Jean-Claude, Ellinor, Patrick T., MacArthur, Daniel G., Lettre, Guillaume, Orkin, Stuart H., Canver, Matthew C.

Volltext