Repeat Expansion Disorders: Mechanisms and Therapeutics von Ellerby, Lisa M.

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Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells von An, Mahru C., Zhang, Ningzhe, Scott, Gary, Montoro, Daniel, Wittkop, Tobias, Mooney, Sean, Melov, Simon, Ellerby, Lisa M.

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Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss von Tracy, Tara E., Sohn, Peter Dongmin, Minami, S. Sakura, Wang, Chao, Min, Sang-Won, Li, Yaqiao, Zhou, Yungui, Le, David, Lo, Iris, Ponnusamy, Ravikumar, Cong, Xin, Schilling, Birgit, Ellerby, Lisa M., Huganir, Richard L., Gan, Li

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Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease von Landles, Christian, Sathasivam, Kirupa, Weiss, Andreas, Woodman, Ben, Moffitt, Hilary, Finkbeiner, Steve, Sun, Banghua, Gafni, Juliette, Ellerby, Lisa M., Trottier, Yvon, Richards, William G., Osmand, Alex, Paganetti, Paolo, Bates, Gillian P.

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Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription von Gao, Rui, Chakraborty, Anirban, Geater, Charlene, Pradhan, Subrata, Gordon, Kara L, Snowden, Jeffrey, Yuan, Subo, Dickey, Audrey S, Choudhary, Sanjeev, Ashizawa, Tetsuo, Ellerby, Lisa M, La Spada, Albert R, Thompson, Leslie M, Hazra, Tapas K, Sarkar, Partha S

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Striatal Cholinergic Dysregulation after Neonatal Decrease in X‐Linked Dystonia Parkinsonism‐Related TAF1 Isoforms von Cirnaru, Maria‐Daniela, Creus‐Muncunill, Jordi, Nelson, Shareen, Lewis, Travis B., Watson, Jaime, Ellerby, Lisa M., Gonzalez‐Alegre, Pedro, Ehrlich, Michelle E.

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Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells von Zhang, Ningzhe, An, Mahru C, Montoro, Daniel, Ellerby, Lisa M

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Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells von Ring, Karen L., An, Mahru C., Zhang, Ningzhe, O’Brien, Robert N., Ramos, Eliana Marisa, Gao, Fuying, Atwood, Robert, Bailus, Barbara J., Melov, Simon, Mooney, Sean D., Coppola, Giovanni, Ellerby, Lisa M.

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Proteomic analysis of X-linked dystonia parkinsonism disease striatal neurons reveals altered RNA metabolism and splicing von Tshilenge, Kizito-Tshitoko, Bons, Joanna, Aguirre, Carlos Galicia, Geronimo-Olvera, Cristian, Shah, Samah, Rose, Jacob, Gerencser, Akos A, Mak, Sally K, Ehrlich, Michelle E, Bragg, D Cristopher, Schilling, Birgit, Ellerby, Lisa M

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TYROBP/DAP12 knockout in Huntington's disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astroglios... von Creus-Muncunill, Jordi, Haure-Mirande, Jean Vianney, Mattei, Daniele, Bons, Joanna, Ramirez, Angie V, Hamilton, B Wade, Corwin, Chuhyon, Chowdhury, Sarah, Schilling, Birgit, Ellerby, Lisa M, Ehrlich, Michelle E

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Matrix Metalloproteinases Are Modifiers of Huntingtin Proteolysis and Toxicity in Huntington's Disease von Miller, John P., Holcomb, Jennifer, Al-Ramahi, Ismael, de Haro, Maria, Gafni, Juliette, Zhang, Ningzhe, Kim, Eugene, Sanhueza, Mario, Torcassi, Cameron, Kwak, Seung, Botas, Juan, Hughes, Robert E., Ellerby, Lisa M.

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Huntingtin interacting proteins are genetic modifiers of neurodegeneration von Kaltenbach, Linda S, Romero, Eliana, Becklin, Robert R, Chettier, Rakesh, Bell, Russell, Phansalkar, Amit, Strand, Andrew, Torcassi, Cameron, Savage, Justin, Hurlburt, Anthony, Cha, Guang-Ho, Ukani, Lubna, Chepanoske, Cindy Lou, Zhen, Yuejun, Sahasrabudhe, Sudhir, Olson, James, Kurschner, Cornelia, Ellerby, Lisa M, Peltier, John M, Botas, Juan, Hughes, Robert E

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Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 von Rao, Rammohan V., Peel, Alyson, Logvinova, Anna, del Rio, Gabriel, Hermel, Evan, Yokota, Takanori, Goldsmith, Paul C., Ellerby, Lisa M., Ellerby, H.Michael, Bredesen, Dale E.

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OXR1 maintains the retromer to delay brain aging under dietary restriction von Wilson, Kenneth A., Bar, Sudipta, Dammer, Eric B., Carrera, Enrique M., Hodge, Brian A., Hilsabeck, Tyler A. U., Bons, Joanna, Brownridge, George W., Beck, Jennifer N., Rose, Jacob, Granath-Panelo, Melia, Nelson, Christopher S., Qi, Grace, Gerencser, Akos A., Lan, Jianfeng, Afenjar, Alexandra, Chawla, Geetanjali, Brem, Rachel B., Campeau, Philippe M., Bellen, Hugo J., Schilling, Birgit, Seyfried, Nicholas T., Ellerby, Lisa M., Kapahi, Pankaj

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Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity von Sorek, Matan, Oweis, Walaa, Nissim-Rafinia, Malka, Maman, Moria, Simon, Shahar, Hession, Cynthia C, Adiconis, Xian, Simmons, Sean K, Sanjana, Neville E, Shi, Xi, Lu, Congyi, Pan, Jen Q, Xu, Xiaohong, Pouladi, Mahmoud A, Ellerby, Lisa M, Zhang, Feng, Levin, Joshua Z, Meshorer, Eran

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Increased Susceptibility of Cytoplasmic over Nuclear Polyglutamine Aggregates to Autophagic Degradation von Iwata, Atsushi, Christianson, John C., Bucci, Mirella, Ellerby, Lisa M., Nukina, Nobuyuki, Forno, Lysia S., Kopito, Ron R., Farquhar, Marilyn Gist

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Neuroglobin-Overexpressing Transgenic Mice Are Resistant to Cerebral and Myocardial Ischemia von Khan, Adil A., Wang, Yaoming, Sun, Yunjuan, Mao, Xiao Ou, Xie, Lin, Miles, Erin, Graboski, Justin, Chen, Sylvia, Ellerby, Lisa M., Jin, Kunlin, Greenberg, David A.

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Altered Expression of Matrix Metalloproteinases and Their Endogenous Inhibitors in a Human Isogenic Stem Cell Model of Huntington's Disease von Naphade, Swati, Embusch, Alexander, Madushani, Kuruwitage Lakshika, Ring, Karen L, Ellerby, Lisa M

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Mitochondrial dysfunction in Huntington’s disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice von Oliveira, Jorge M. A., Jekabsons, Mika B., Chen, Sylvia, Lin, Amy, Rego, A. Cristina, Gonçalves, Jorge, Ellerby, Lisa M., Nicholls, David G.

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FGF-2 Promotes Neurogenesis and Neuroprotection and Prolongs Survival in a Transgenic Mouse Model of Huntington's Disease von Jin, Kunlin, Michelle La Fevre-Bernt, Sun, Yunjuan, Chen, Sylvia, Juliette Gafni, Danielle Crippen, Logvinova, Anna, Ross, Christopher A., Greenberg, David A., Ellerby, Lisa M.

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