Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2 von Inoue, Satoshi, Li, Wanda Y., Tseng, Alan, Beerman, Isabel, Elia, Andrew J., Bendall, Sean C., Lemonnier, François, Kron, Ken J., Cescon, David W., Hao, Zhenyue, Lind, Evan F., Takayama, Naoya, Planello, Aline C., Shen, Shu Yi, Shih, Alan H., Larsen, Dana M., Li, Qinxi, Snow, Bryan E., Wakeham, Andrew, Haight, Jillian, Gorrini, Chiara, Bassi, Christian, Thu, Kelsie L., Murakami, Kiichi, Elford, Alisha R., Ueda, Takeshi, Straley, Kimberly, Yen, Katharine E., Melino, Gerry, Cimmino, Luisa, Aifantis, Iannis, Levine, Ross L., De Carvalho, Daniel D., Lupien, Mathieu, Rossi, Derrick J., Nolan, Garry P., Cairns, Rob A., Mak, Tak W.

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Hypoxia-inducible factor 1 alpha limits dendritic cell stimulation of CD8 T cell immunity von Tran, Charles W, Gold, Matthew J, Garcia-Batres, Carlos, Tai, Kelly, Elford, Alisha R, Himmel, Megan E, Elia, Andrew J, Ohashi, Pamela S

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Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity von Lang, Philipp A, Lang, Karl S, Xu, Haifeng C, Grusdat, Melanie, Parish, Ian A, Recher, Mike, Elford, Alisha R, Dhanji, Salim, Shaabani, Namir, Tran, Charles W, Dissanayake, Dilan, Rahbar, Ramtin, Ghazarian, Magar, Brüstle, Anne, Fine, Jason, Chen, Peter, Weaver, Casey T, Klose, Christoph, Diefenbach, Andreas, Häussinger, Dieter, Carlyle, James R, Kaech, Susan M, Mak, Tak W, Ohashi, Pamela S

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IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology von Pellegrini, Marc, Calzascia, Thomas, Toe, Jesse G., Preston, Simon P., Lin, Amy E., Elford, Alisha R., Shahinian, Arda, Lang, Philipp A., Lang, Karl S., Morre, Michel, Assouline, Brigitte, Lahl, Katharina, Sparwasser, Tim, Tedder, Thomas F., Paik, Ji-hye, DePinho, Ronald A., Basta, Sameh, Ohashi, Pamela S., Mak, Tak W.

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CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity von Calzascia, Thomas, Pellegrini, Marc, Lin, Albert, Garza, Kristine M, Elford, Alisha R, Shahinian, Arda, Ohashi, Pamela S, Mak, Tak W

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Overproduction of IL-2 by Cbl-b deficient CD4+ T cells provides resistance against regulatory T cells von Han, SeongJun, Chung, Douglas C., St. Paul, Michael, Liu, Zhe Qi, Garcia-Batres, Carlos, Elford, Alisha R., Tran, Charles W., Chapatte, Laurence, Ohashi, Pamela S.

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NK Cells Regulate CD8 + T Cell Mediated Autoimmunity von Lang, Philipp A, Crome, Sarah Q, Xu, Haifeng C, Lang, Karl S, Chapatte, Laurence, Deenick, Elissa K, Grusdat, Melanie, Pandyra, Aleksandra A, Pozdeev, Vitaly I, Wang, Ruifeng, Holderried, Tobias A W, Cantor, Harvey, Diefenbach, Andreas, Elford, Alisha R, McIlwain, David R, Recher, Mike, Häussinger, Dieter, Mak, Tak W, Ohashi, Pamela S

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Exposure to sequestered self-antigens in vivo is not sufficient for the induction of autoimmune diabetes von Ono, Nobuyuki, Murakami, Kiichi, Chan, Olivia, Hall, Håkan, Elford, Alisha R, Yen, Patty, Calzascia, Thomas, Spencer, David M, Ohashi, Pamela S, Dhanji, Salim

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Peptide-pulsed dendritic cells have superior ability to induce immune-mediated tissue destruction compared to peptide with adjuvant von Dissanayake, Dilan, Murakami, Kiichi, Tran, Michael D, Elford, Alisha R, Millar, Douglas G, Ohashi, Pamela S

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Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus von Liadis, Nicole, Murakami, Kiichi, Eweida, Mohamed, Elford, Alisha R., Sheu, Laura, Gaisano, Herbert Y., Hakem, Razqallah, Ohashi, Pamela S., Woo, Minna

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Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges von Lind, Evan F, Elford, Alisha R, Ohashi, Pamela S

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Different toll-like receptor stimuli have a profound impact on cytokines required to break tolerance and induce autoimmunity von Lin, Albert C C, Dissanayake, Dilan, Dhanji, Salim, Elford, Alisha R, Ohashi, Pamela S

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Coenzyme A fuels T cell anti-tumor immunity von St Paul, Michael, Saibil, Samuel D, Han, SeongJun, Israni-Winger, Kavita, Lien, Scott C, Laister, Rob C, Sayad, Azin, Penny, Susanne, Amaria, Rodabe N, Haydu, Lauren E, Garcia-Batres, Carlos R, Kates, Meghan, Mulder, David T, Robert-Tissot, Céline, Gold, Matthew J, Tran, Charles W, Elford, Alisha R, Nguyen, Linh T, Pugh, Trevor J, Pinto, Devanand M, Wargo, Jennifer A, Ohashi, Pamela S

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Choline acetyltransferase-expressing T cells are required to control chronic viral infection von Cox, Maureen A, Duncan, Gordon S, Lin, Gloria H Y, Steinberg, Benjamin E, Yu, Lisa X, Brenner, Dirk, Buckler, Luke N, Elia, Andrew J, Wakeham, Andrew C, Nieman, Brian, Dominguez-Brauer, Carmen, Elford, Alisha R, Gill, Kyle T, Kubli, Shawn P, Haight, Jillian, Berger, Thorsten, Ohashi, Pamela S, Tracey, Kevin J, Olofsson, Peder S, Mak, Tak W

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Peptide‐activated double‐negative T cells can prevent autoimmune type‐1 diabetes development von Ford, Megan S., Chen, Wenhao, Wong, Sophie, Li, Carmen, Vanama, Ramesh, Elford, Alisha R., Asa, Sylvia L., Ohashi, Pamela S., Zhang, Li

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Activation of Peroxisome Proliferator-Activated Receptors α and δ Synergizes with Inflammatory Signals to Enhance Adoptive Cell Therapy von Saibil, Samuel D, St Paul, Michael, Laister, Robert C, Garcia-Batres, Carlos R, Israni-Winger, Kavita, Elford, Alisha R, Grimshaw, Natasha, Robert-Tissot, Céline, Roy, Dominic G, Jones, Russell G, Nguyen, Linh T, Ohashi, Pamela S

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Phase II clinical trial of adoptive cell therapy for patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and low-dose interleukin-2 von Nguyen, Linh T., Saibil, Samuel D., Sotov, Valentin, Le, Michael X., Khoja, Leila, Ghazarian, Danny, Bonilla, Luisa, Majeed, Habeeb, Hogg, David, Joshua, Anthony M., Crump, Michael, Franke, Norman, Spreafico, Anna, Hansen, Aaron, Al-Habeeb, Ayman, Leong, Wey, Easson, Alexandra, Reedijk, Michael, Goldstein, David P., McCready, David, Yasufuku, Kazuhiro, Waddell, Thomas, Cypel, Marcelo, Pierre, Andrew, Zhang, Bianzheng, Boross-Harmer, Sarah, Cipollone, Jane, Nelles, Megan, Scheid, Elizabeth, Fyrsta, Michael, Lo, Charlotte S., Nie, Jessica, Yam, Jennifer Y., Yen, Pei Hua, Gray, Diana, Motta, Vinicius, Elford, Alisha R., DeLuca, Stephanie, Wang, Lisa, Effendi, Stephanie, Ellenchery, Ragitha, Hirano, Naoto, Ohashi, Pamela S., Butler, Marcus O.

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DNA damage- and stress-induced apoptosis occurs independently of PIDD von Kim, Ira R, Murakami, Kiichi, Chen, Nien-Jung, Saibil, Samuel D, Matysiak-Zablocki, Elzbieta, Elford, Alisha R, Bonnard, Madeleine, Benchimol, Samuel, Jurisicova, Andrea, Yeh, Wen-Chen, Ohashi, Pamela S

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Translational Control by 4E-BP1/2 Suppressor Proteins Regulates Mitochondrial Biosynthesis and Function during CD8 + T Cell Proliferation von Dimitriou, Ioannis D, Meiri, David, Jitkova, Yulia, Elford, Alisha R, Koritzinsky, Marianne, Schimmer, Aaron D, Ohashi, Pamela S, Sonenberg, Nahum, Rottapel, Robert

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CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly von Jones, Russell G, Elford, Alisha R, Parsons, Michael J, Wu, Linda, Krawczyk, Connie M, Yeh, Wen-Chen, Hakem, Razqallah, Rottapel, Robert, Woodgett, James R, Ohashi, Pamela S

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